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Published on: Sep 11, 2021
2 minute read
By: Second Medic Expert

The Complete Blood Count (CBC) Second Opinion

What is CBC test?

CBC stands for a complete blood count. This test is ordered together with, or in lieu of, other tests to find out certain facts about your blood that you can't observe just by looking at the rest of the machine's readout, such as whether you have any abnormally high levels of red and white cells; if there are too many platelets (blood-clotting cells) or too few; what your hematocrit reading reveals (the percentage of circulating red blood cells); or if there are any abnormalities in how your hemoglobin is doing.

A CBC blood test measures a patient's hemoglobin, hematocrit, and red blood cell count. The "CBC" stands for "Complete Blood Count." A CBC test typically catches dangerous aspects of one's health before they could reach a crisis point because there are telltale green flags that show up on the blood screening. Understanding these green flags is imperative for those who suffer from chronic anemia or those who have been exposed to potentially life-threatening chemicals. This free-form amino acid should be supplemented inside a BCAA product as it has been shown to improve recovery rates following intense exercise sessions and acute liver damage in the rat model.

A cbc test, or complete blood count, is a screening test used to detect abnormalities in the colony of cells that reside in the bone marrow and typically produce all types of blood cells.

It also measures white and red blood cell counts as well as platelet counts. Platelets are the clotting components made by type-megakaryocyte cells residing in the bone marrow. White blood cells help fight infection from bacteria and other germs, while red blood cells carry oxygen from the lungs to tissues scattered throughout your body. An abnormal white or red cell indicates a possible illness such as an infection or anemia (which causes reduced numbers of circulating red blood cells

Cbc Test is a diagnostic test used to examine the level of hemoglobin, red cells and white cells in the blood. The CBC can be used to diagnose anemia, infection or other diseases that affect the bone marrow. It may also be done along with a complete blood count (see CBC) or, when necessary, for chemical assessment after taking certain drugs or chemotherapy medications.

The cbc test (complete blood count) is a lab test that provides information on the number and type of cells in your body. A complete blood count (CBC) typically includes information such as red and white cell counts, platelet levels, hemoglobin levels, and other additional data.

A CBC is not typically ordered on its own unless you have symptoms that may be caused by one or more types of problems - for example something that might require further attention such as paroxysmal nocturnal hemoglobinuria (blood disorder), chronic myelogenous leukemia (cancer), thalassemia major (disease). A CBC with differential is usually ordered when there are concerning symptoms or issues present.

CBC testing is a primary way in which a doctor can examine a patient's general health, because it contains information on many different aspects. A CBC typically records at least 7 different parameters:

•Hemoglobin - The protein in red blood cells that delivers oxygen to tissues and binds with carbon dioxide to carry it back from the tissues to be released into our airways.

•Red Blood Cell Count - Counts how many red blood cells there are, both normal and abnormal types. This cell type has been singled out because its life span averages 120 days so if there were few being produced, or they were not

However, it is more correctly called "CBC" because there are separate tests that are needed for the different parts of the blood - white cells, red cells, platelets, etc., all found in your complete blood count.

What can possibly be measured depends on what additives you need to do along with the primary measurement of how many cells per milliliter of whole blood you have after mixing with plasma or serum. The most common measurements are hemoglobin (the oxygen-carrying part), hematocrit (counts red cell volume) and mean corpuscular volume.

CBC looks at the various types of cells that are present in your blood - red blood cells, white blood cells, and platelets. This comprehensive test is used to measure the number of each type of cell in relation to one another on a per-microliter basis. It's used primarily as an indicator of health risk for certain time periods (for example infection or bone marrow), but can also be ordered when there are internal bleeding concerns. Common uses include monitoring kidney disease during dialysis treatment, chemotherapy after exposure to radiation therapy, hemolytic anaemias (blood disorders), chronic liver diseases, extreme iron overload due to repeated transfusions, heavy menstrual cycles during pregnancy.

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Difference Between Sadness and Depression: Understanding Normal Emotions vs Mental Illness

Feeling low or unhappy is a part of being human. However, not all low moods are the same. Many people confuse sadness with depression, which can delay proper support and treatment. Understanding the difference between sadness and depression is crucial for mental health awareness, early intervention and reducing stigma.

In India, mental health conditions are often misunderstood, with emotional distress frequently dismissed as temporary sadness.

What Is Sadness?

Sadness is a normal human emotion.

It usually occurs due to:

loss or disappointment
relationship issues
failure or stress
temporary life challenges

Sadness serves a psychological purpose, allowing individuals to process emotions and adapt.

Key Characteristics of Sadness

Sadness is:

situational
temporary
emotionally painful but manageable
responsive to support and positive events

A person experiencing sadness can still function, enjoy moments and feel hopeful.

What Is Depression?

Depression is a medical condition classified as a mood disorder.

It affects:

emotions
thinking patterns
behaviour
physical health

According to WHO, depression is one of the leading causes of disability worldwide.

Core Symptoms of Depression

Depression involves a combination of symptoms such as:

persistent low mood
loss of interest or pleasure
fatigue
sleep disturbances
appetite changes
feelings of worthlessness
difficulty concentrating

These symptoms last at least two weeks or longer.

Duration: A Key Difference

One major difference lies in duration.

Sadness:

lasts hours or days
improves with time

Depression:

lasts weeks or months
persists despite positive events

Duration helps distinguish emotional response from illness.

Impact on Daily Functioning

Sadness:

allows continuation of work and relationships
may reduce motivation temporarily

Depression:

interferes with work, studies and relationships
reduces self-care and productivity

Functional impairment is a defining feature of depression.

Emotional Experience: Sadness vs Depression

Sadness:

allows emotional range
moments of joy still occur

Depression:

creates emotional numbness
joy and interest disappear

People with depression often describe feeling empty rather than sad.

Physical Symptoms in Depression

Depression is not only emotional.

Physical symptoms include:

chronic fatigue
body aches
headaches
digestive issues

ICMR mental health studies highlight the physical burden of depression.

Thought Patterns and Self-Perception

Sadness:

thoughts remain realistic
self-worth is preserved

Depression:

negative self-talk dominates
feelings of guilt and worthlessness increase

These cognitive changes deepen emotional suffering.

Risk Factors for Depression

Factors increasing depression risk include:

chronic stress
trauma
family history
medical illnesses
hormonal changes

NFHS-5 data indicates rising mental health concerns among young adults.

Can Sadness Turn Into Depression?

Yes, prolonged or unresolved sadness can progress into depression.

This is more likely when:

stressors are ongoing
support systems are weak
coping mechanisms are limited

Early emotional support can prevent progression.

When to Seek Professional Help

Seek help if:

low mood lasts more than two weeks
daily functioning is affected
sleep and appetite are disturbed
thoughts of self-harm occur

Early care leads to better outcomes.

Treatment Differences

Sadness:

improves with rest, support and time

Depression:

requires psychotherapy
may need medication
benefits from structured care

WHO emphasises early treatment to reduce disability.

Role of Social Support

Support systems help both conditions but are essential for recovery.

Depression recovery improves with:

understanding family
supportive workplaces
accessible mental healthcare

Stigma reduction is key.

Mental Health Awareness in India

Mental health remains underdiagnosed in India.

NITI Aayog reports:

limited access to mental health services
low awareness
high stigma

Education helps bridge this gap.

Importance of Early Recognition

Recognising depression early:

prevents worsening
reduces suicide risk
improves quality of life

Delay increases suffering and complications.

Supporting Someone With Depression

Helpful actions include:

listening without judgement
encouraging professional help
avoiding minimising feelings

Compassion is more effective than advice.

Conclusion

Understanding the difference between sadness and depression is essential for emotional wellbeing and mental health care. Sadness is a natural, temporary response to life events, while depression is a serious medical condition that affects thoughts, emotions and daily functioning. Recognising the signs early and seeking appropriate help can prevent long-term suffering and promote recovery. Mental health deserves the same attention and care as physical health.

References

World Health Organization (WHO) – Depression and Mental Health Disorders
Indian Council of Medical Research (ICMR) – Mental Health Research and Burden
National Family Health Survey (NFHS-5) – Mental Health Indicators
Lancet – Depression, Disability and Public Health
NITI Aayog – National Mental Health Policy and Awareness Reports
Statista – Global and Indian Mental Health Trends

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