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Published on: Sep 11, 2021
2 minute read
By: Second Medic Expert

The Complete Blood Count (CBC) Second Opinion

What is CBC test?

CBC stands for a complete blood count. This test is ordered together with, or in lieu of, other tests to find out certain facts about your blood that you can't observe just by looking at the rest of the machine's readout, such as whether you have any abnormally high levels of red and white cells; if there are too many platelets (blood-clotting cells) or too few; what your hematocrit reading reveals (the percentage of circulating red blood cells); or if there are any abnormalities in how your hemoglobin is doing.

A CBC blood test measures a patient's hemoglobin, hematocrit, and red blood cell count. The "CBC" stands for "Complete Blood Count." A CBC test typically catches dangerous aspects of one's health before they could reach a crisis point because there are telltale green flags that show up on the blood screening. Understanding these green flags is imperative for those who suffer from chronic anemia or those who have been exposed to potentially life-threatening chemicals. This free-form amino acid should be supplemented inside a BCAA product as it has been shown to improve recovery rates following intense exercise sessions and acute liver damage in the rat model.

A cbc test, or complete blood count, is a screening test used to detect abnormalities in the colony of cells that reside in the bone marrow and typically produce all types of blood cells.

It also measures white and red blood cell counts as well as platelet counts. Platelets are the clotting components made by type-megakaryocyte cells residing in the bone marrow. White blood cells help fight infection from bacteria and other germs, while red blood cells carry oxygen from the lungs to tissues scattered throughout your body. An abnormal white or red cell indicates a possible illness such as an infection or anemia (which causes reduced numbers of circulating red blood cells

Cbc Test is a diagnostic test used to examine the level of hemoglobin, red cells and white cells in the blood. The CBC can be used to diagnose anemia, infection or other diseases that affect the bone marrow. It may also be done along with a complete blood count (see CBC) or, when necessary, for chemical assessment after taking certain drugs or chemotherapy medications.

The cbc test (complete blood count) is a lab test that provides information on the number and type of cells in your body. A complete blood count (CBC) typically includes information such as red and white cell counts, platelet levels, hemoglobin levels, and other additional data.

A CBC is not typically ordered on its own unless you have symptoms that may be caused by one or more types of problems - for example something that might require further attention such as paroxysmal nocturnal hemoglobinuria (blood disorder), chronic myelogenous leukemia (cancer), thalassemia major (disease). A CBC with differential is usually ordered when there are concerning symptoms or issues present.

CBC testing is a primary way in which a doctor can examine a patient's general health, because it contains information on many different aspects. A CBC typically records at least 7 different parameters:

•Hemoglobin - The protein in red blood cells that delivers oxygen to tissues and binds with carbon dioxide to carry it back from the tissues to be released into our airways.

•Red Blood Cell Count - Counts how many red blood cells there are, both normal and abnormal types. This cell type has been singled out because its life span averages 120 days so if there were few being produced, or they were not

However, it is more correctly called "CBC" because there are separate tests that are needed for the different parts of the blood - white cells, red cells, platelets, etc., all found in your complete blood count.

What can possibly be measured depends on what additives you need to do along with the primary measurement of how many cells per milliliter of whole blood you have after mixing with plasma or serum. The most common measurements are hemoglobin (the oxygen-carrying part), hematocrit (counts red cell volume) and mean corpuscular volume.

CBC looks at the various types of cells that are present in your blood - red blood cells, white blood cells, and platelets. This comprehensive test is used to measure the number of each type of cell in relation to one another on a per-microliter basis. It's used primarily as an indicator of health risk for certain time periods (for example infection or bone marrow), but can also be ordered when there are internal bleeding concerns. Common uses include monitoring kidney disease during dialysis treatment, chemotherapy after exposure to radiation therapy, hemolytic anaemias (blood disorders), chronic liver diseases, extreme iron overload due to repeated transfusions, heavy menstrual cycles during pregnancy.

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How Lack of Sleep Weakens Immunity: Why Poor Sleep Makes You Fall Sick More Often

Sleep is one of the most powerful yet overlooked pillars of health. While nutrition and exercise receive significant attention, sleep often takes a back seat in modern lifestyles. Understanding how lack of sleep weakens immunity reveals why people who sleep poorly fall sick more often, take longer to recover and experience chronic inflammation.

In India, late-night work culture, excessive screen time and irregular schedules have made sleep deprivation increasingly common across age groups.

The Link Between Sleep and the Immune System

The immune system relies on sleep for:

repair and regeneration
immune cell production
inflammation control

During deep sleep, the body releases cytokines and antibodies that protect against infections.

What Happens to Immunity During Sleep

While sleeping:

immune cells identify pathogens
inflammatory responses are regulated
memory T-cells strengthen immune memory

This nightly process prepares the body to fight infections effectively.

How Sleep Deprivation Disrupts Immune Function

When sleep is inadequate:

immune cell activity decreases
antibody production drops
inflammation increases

WHO studies confirm that sleep deprivation weakens immune defence mechanisms.

Increased Risk of Infections

People who sleep less than 6 hours regularly:

fall sick more often
catch colds and flu easily
recover slower from illness

Lancet research shows a strong link between sleep duration and infection susceptibility.

Impact on Inflammation

Poor sleep increases inflammatory markers.

Chronic inflammation:

weakens immune response
increases risk of chronic diseases

ICMR reports highlight sleep deprivation as a contributor to low-grade systemic inflammation.

Effect on Vaccine Response

Sleep quality affects how well vaccines work.

Studies show:

poor sleep reduces antibody response
adequate sleep improves vaccine effectiveness

Sleep is essential for immune memory formation.

Hormonal Changes That Affect Immunity

Sleep regulates hormones such as:

cortisol
melatonin

Lack of sleep increases cortisol, which suppresses immune function.

Stress, Sleep and Immunity

Sleep deprivation and stress reinforce each other.

High stress:

disrupts sleep
suppresses immune cells

This cycle weakens overall resistance to illness.

Impact on Gut Immunity

The gut hosts a major part of the immune system.

Poor sleep:

disrupts gut microbiome
weakens gut immunity

Lancet studies link sleep deprivation to gut-related immune dysfunction.

Why Children and Older Adults Are More Vulnerable

Sleep deprivation affects:

children’s developing immune systems
older adults’ already weakened immunity

Adequate sleep is especially important in these age groups.

Signs Your Immunity Is Affected by Poor Sleep

Warning signs include:

frequent infections
slow wound healing
constant fatigue
increased allergies

These symptoms indicate compromised immune defence.

Long-Term Health Risks of Poor Sleep

Chronic sleep deprivation increases risk of:

infections
autoimmune disorders
metabolic diseases
heart disease

Sleep loss affects nearly every body system.

Role of Preventive Health Awareness

Preventive healthcare emphasises:

sleep as a foundation of immunity
early lifestyle correction

NITI Aayog recognises sleep hygiene as essential for population health.

How to Improve Sleep for Better Immunity

Effective strategies include:

fixed sleep and wake times
limiting screen exposure before bed
avoiding caffeine late in the day
creating a dark, quiet sleep environment

Consistency matters more than duration alone.

Myths About Sleep and Immunity

Myth: You can catch up on sleep later
Fact: Chronic sleep debt harms immunity.

Myth: Sleeping pills improve immunity
Fact: Natural sleep is more beneficial.

Why Sleep Is a Preventive Medicine

Sleep:

costs nothing
requires no equipment
delivers powerful immune protection

It is one of the most effective preventive health tools.

Conclusion

Understanding how lack of sleep weakens immunity highlights the critical role of sleep in protecting the body from infections and chronic disease. Poor sleep disrupts immune cell function, increases inflammation and reduces resistance to illness. Prioritising consistent, quality sleep is not optional—it is essential for strong immunity, faster recovery and long-term health. Protecting sleep today strengthens immune defence for tomorrow.

References

Indian Council of Medical Research (ICMR) – Sleep, Immunity and Inflammation Studies
World Health Organization (WHO) – Sleep and Immune Health Guidelines
National Institutes of Health – Sleep Deprivation and Immunity
Lancet – Sleep Duration and Infection Risk
NITI Aayog – Preventive Health and Lifestyle Recommendations

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