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Published on: Jan 02, 2021
2 minute read
By: Dr Rajan Choudhary

COVID-19 Variant: What We Know About This New Mutation

COVID-19 Variant: What we know about this new mutation

In early December a new variant of COVID -19 was detected in the UK, raising concerns across the world. SARS-CoV-2 has already significantly impacted the world, with 84 million cases worldwide and nearly 2 million deaths. Could the new variant cause further havoc? Is it something we should be worried about? Today we will have a look at what we know so far about the virus.

MUTAGENESIS

To start with we should go over viral mutations. Unlike complex organisms, viruses are highly prone to genetic mutations, even more than bacteria. All organisms including humans, birds, even worms, are prone to mutations as well. However due to their complexity, there is much higher risk of mutations causing significant problems with their cellular and genetic processes, problems that are often incompatible with life, or lead to cancer. For this reason, there are significant genetic roadblocks present to prevent such mutations from occurring.

Viruses on the other hand have genetic replication machinery of poor “quality”, prone to introducing mutations. Since they replicate quickly, with little care on which viral particles survive, it matters little if hundreds of viruses do not survive, as further thousands will and continue to spread in their host. It is for this reason we have such difficulty treating viruses or making viruses against them .

COVID VARIANT

The variant was first picked up by the COVID-19 Genomics UK consortium, which undertakes random genetic sequencing of positive COVID-19 samples across the UK. Since April they have sequenced 140,000 virus genomes, to identify and track outbreaks across the UK. The strain was first identified in September and sequenced in early October. However, the significance of this strain was not realized until the end of the year. By 13th December 1108 cases had been identified across 60 different locations, though the true number is likely much higher. In Norfolk, it accounts for nearly 20% of all samples.

17 Variations have been identified, most significantly in the spike protein the virus uses to bind to the ACE2 receptor found in the lungs. Changes in this protein may have resulted in it being more infectious and spreading more quickly between people. A review of current evidence has shown the rate of transmission was 71% higher than the other variants and may also have a much higher viral load. This has given it an advantage over the other COVID-19 strains- it has already been detected in South Africa, Europe, and America, and it is likely to become the dominant global strain in the near future.

It appears children are more susceptible to catching this virus. The virus propagated at a time when schools were open and running, whilst the rest of the country remained in lockdown. This may have provided a larger pool of children for the virus to spread in, resulting in this change. However, this does not mean that the virus “attacks” children, rather it is able to attach to ACE2 receptors in children’s lungs with greater ease and spread quickly.

VACCINE

The most important question on everyone’s mind – will the vaccine be effective against this new strain? If not, lockdown rules may be extended until new vaccines are discovered, and by then newer strains may leapfrog ahead and make the new vaccines irrelevant again.

So far experts believe that the new variant is unlikely to make vaccines ineffective. The vaccines all produce antibodies against the viral spike protein, but so far it appears the mutation has not changed the shape or function of the spike protein enough for antibodies to fail against it. The antibodies should be able to recognize enough sites on the spike protein to successfully attach, neuter the protein, and present the virus for destruction by the body’s immune system. Unfortunately, it will take some time to fully understand the effects of the mutation, though we can remain hopeful for now

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National Dentist Day: Best Oral Hygiene Tips Shared by Experts

Every year, on March 6th, National Dentist Day is celebrated to recognize the invaluable contributions of dentists in maintaining our oral health. This special day also serves as a reminder of the importance of good oral hygiene habits. Whether you're looking to improve your daily dental routine or seeking expert advice, we’ve compiled the best oral hygiene tips shared by dentists to help you achieve a healthy and confident smile.

1. Brush Properly, Not Just Regularly

Brushing twice a day is essential, but how you brush matters just as much as how often. Experts recommend using a soft-bristled toothbrush and fluoride toothpaste. Follow these steps for effective brushing:

Use a gentle, circular motion rather than scrubbing.
Brush for at least two minutes twice a day.
Ensure you clean all tooth surfaces, including the back molars and gum line.

2. Flossing is Non-Negotiable

Flossing removes food particles and plaque from between your teeth where your toothbrush can’t reach. Dentists suggest flossing at least once a day to prevent cavities and gum disease. If traditional flossing is difficult, consider using:

Water flossers
Interdental brushes
Floss picks

3. Rinse with Mouthwash for Extra Protection

Using an antibacterial mouthwash helps reduce plaque, prevents bad breath, and protects against gum disease. Look for a fluoride-based or alcohol-free mouthwash, especially if you have sensitive gums.

Tip: Rinse for 30 seconds after brushing and flossing for best results.

4. Eat a Tooth-Friendly Diet

What you eat significantly impacts your oral health. Dentists recommend incorporating the following foods into your diet:

Dairy products (milk, cheese, yogurt) to strengthen enamel.
Crunchy fruits and vegetables (apples, carrots) to naturally clean teeth.
Nuts and seeds for essential minerals like calcium and phosphorus.
Green tea for its antibacterial properties.

Avoid excessive consumption of sugary snacks, acidic beverages, and sticky candies, which can erode enamel and lead to cavities.

5. Stay Hydrated and Limit Sugary Drinks

Drinking plenty of water helps wash away food particles and bacteria, keeping your mouth fresh and clean. Limit soda, sports drinks, and coffee, as they can stain teeth and contribute to decay.

Pro Tip: If you drink sugary or acidic beverages, use a straw to minimize direct contact with your teeth.

6. Replace Your Toothbrush Regularly

A worn-out toothbrush is ineffective at cleaning your teeth. Dentists recommend replacing your toothbrush every 3-4 months or sooner if the bristles are frayed. Using an electric toothbrush can also improve plaque removal.

7. Schedule Regular Dental Checkups

No matter how diligent your oral hygiene routine is, visiting your dentist every six months is crucial for professional cleanings and early detection of dental issues. Regular checkups can help prevent cavities, gum disease, and even serious health conditions linked to poor oral health.

8. Protect Your Teeth While Playing Sports

If you engage in contact sports, wearing a custom-fitted mouthguard can protect your teeth from injuries and fractures. This simple preventive measure can save you from costly dental treatments.

9. Avoid Smoking and Tobacco Products

Smoking and tobacco use are major contributors to gum disease, tooth loss, and oral cancer. If you’re looking for another reason to quit, your oral health is a great motivation. Talk to your dentist about resources to help you quit.

10. Teach Kids Good Oral Hygiene Habits Early

Children should learn proper oral hygiene habits from a young age. Encourage them to:

Brush their teeth with fluoride toothpaste.
Floss regularly.
Visit the dentist every six months.
Avoid excessive sweets and sugary drinks.

Setting a strong foundation for oral health can prevent future dental issues and ensure a lifetime of healthy smiles.

Conclusion

This National Dentist Day, take the opportunity to improve your oral care routine by following these expert tips. Good oral hygiene isn’t just about having a bright smile—it’s also essential for overall health and well-being. Show appreciation for your dentist by prioritizing your dental health and scheduling your next checkup.

For personalized dental care advice, consult a professional at SecondMedic, where expert guidance helps you maintain optimal oral health.