Call
+918447748545

Published on: Apr 30, 2020
3 minute read
By: Dr Rajan Choudhary

COVID AND CLOTTING: A BRIEF LOOK

At the Mount Sinai hospital, a case series of five patients have been put together, ready to be published in the New England Journal of Medicine. It details patients aged 33, 37, 39, 44, and 49 who all began to experience a sudden onset of symptoms including slurred speech, confusion, drooping on one side of the face, and feeling dead in one arm. At the time of writing one has sadly died, two remain hospitalized and one is in rehab. Only the youngest is able to speak. All of them were found to be COVID positive.

This drastic case series highlights a growing problem of strokes and clotting disorders in COVID patients, one noted by medics across the world. This blog looks at whether this is a common occurrence and what may be causing it.

Before reading this blog it will be helpful to read our previous blog on why and how blood clots.

THE START

In mid-February Tang et al published a paper noting that patients with abnormal clotting parameters were associated with a poorer prognosis. In their study, 11% of their patients died, but out of these patients, 71% had these abnormal parameters, compared to just 0.6% of survivors. The patients who died also demonstrated DIC (disseminated intravascular coagulation), a condition in which clotting is triggered in the patients' blood across the body, not just at the site of injury.

There is one major issue with this study. In most European hospitals patients receive anticoagulant medications on a daily basis. This is because lying in a hospital bed when ill can promote the formation of clots in your legs. Most hospitals in China do not provide this anticoagulation, but even then the incidence of clotting is remarkably high.

After this, the evidence begins piling up. 9th April, Cui et al found 25% of patients with severe COVID had clots in their legs, of which just under half died. Looking at a specific clotting parameter (D-DIMER) was remarkably accurate at predicting high-risk patients.

Italian doctors found in 16 patients in critical care with severe Acute Respiratory Distress Syndrome (a severe inflammatory condition caused by COVID) also had deranged clotting parameters.

French studies had found these sickest patients often had large clots in their lungs, blocking blood flow in the lung and causing severe issues in keeping the patient's blood well oxygenated.

Some studies showed even patients hooked up to artificial lungs (known as ECMO) were not safe from the problems caused by excessive clotting.

WHY?

So why is this occurring? As with everything in medicine, the answer is complicated and usually multifactorial. So we will simplify it.

We must look at the platelets in our blood. These fragmented cells have an important role in triggering the clotting cascade and creating a clot. During an infection white blood cells (important immune cells responsible for finding and destroying invading organisms) release many chemical signals around an infection site. This triggers platelets, the formation of small protein meshes that can literally net the viral particles in the blood.

But it looks like they have an anti-viral role as well. Researchers have found specialist receptors on platelets that recognize viruses in the blood, leading to the release of specialist anti-viral molecules that target and destroy the viruses. This is an interesting finding because it is white blood cells that are known to destroy invading organisms.

So how does it go wrong? In severe infections, there is a very large viral load, and this can cause an excessive response. Too many white blood cells release too many chemical signals, causing too many platelets to activate. The same thing can occur with the virus directly activating too many platelets at once. This results in clots forming in the blood throughout the body, including the lung and the brain. It is another instance of the body falling victim to its own protective mechanism.

A second problem is that as these platelets are activated, they and the clotting proteins in the patient’s blood are “used up”. This is dangerous, because without these platelets and clotting proteins the body is unable to stop any bleeding sites. Profuse bleeding can occur from small injuries, further complicating the treatment of the patient.

So what can be done?

Hospitals have already started looking at giving patients with severe COVID anticoagulation therapy. And it seems in patients with deranged clotting, giving anticoagulation therapy can lower mortality. The International Society on Thrombosis and Haemostasis (Clotting) has recommended that patients with severe COVID receive high dose anticoagulation medication to thin their blood, because these patients are at such high risk of clots. This regime will be used for hospital patients and those in critical care.

And what about for the everyday public? Should we be worried? So far the data suggests this is only happening in people suffering from severe symptoms of COVID. But the incident in New York certainly raises some questions, and it will be interesting to read their report in NEMJ. Should you panic and start taking anti-coagulant medication at home? Definitely not. But what you should do is be educated in the symptoms of common diseases caused by clots. Diseases such as strokes and DVTs.

STROKE

Remember, act F.A.S.T

Facial Droop on one side
Arm or hand on one side feels numb or weak with reduced power (same in one leg)
Slurred speech making it difficult to understand
Time to phone an ambulance

Other symptoms can include sudden loss in balance, sudden loss in vision in one eye, problems swallowing, and more.

DVT

Look out for a swollen, painful calf on one side that is hot to touch.

PULMONARY EMBOLISM

If you have a swollen, painful calf and are also having trouble breathing, with some sharp stabbing pain in your chest, contact the emergency services as soon as possible.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

Read Blog

Digital Healthcare Automation India: Enabling Smart Workflows, Faster Care, and a Modern Clinical Ecosystem

Digital healthcare automation is redefining how India delivers medical services, manages clinical operations, and coordinates patient journeys. As hospitals, clinics, and digital health platforms move toward technology-driven processes, automation has become essential for ensuring efficiency, reducing manual work, minimizing delays, and improving care accuracy. In a healthcare system where patient volumes are high and specialist availability is uneven, automation empowers organizations to deliver faster, smarter, and more consistent care.

India’s healthcare automation growth aligns with national initiatives like ABDM (Ayushman Bharat Digital Mission), growing telemedicine adoption, rising digital literacy, and the increased use of AI-based medical tools. SecondMedic integrates automation into every stage of digital care-appointments, reporting, monitoring, follow-ups, and preventive health-allowing users and clinicians to experience a seamless, intelligent healthcare ecosystem.

Digital healthcare automation India is not simply about digitizing manual tasks; it is about augmenting healthcare with intelligent workflows that respond to real-time needs. By reducing repetitive workloads, automation allows clinicians to focus on what matters most: patient care.

Why Automation Matters in Indian Healthcare

India faces significant challenges: overloaded outpatient departments, resource shortages, manual data entry errors, delayed reports, and administrative inefficiencies. Automation addresses these issues by introducing structured, rule-based processes supported by AI and digital tools.

Key systemic challenges automation helps solve:

High patient-to-doctor ratios
Slow movement of information across departments
Inconsistent follow-up and monitoring
Manual errors in documentation and reporting
Unpredictable appointment flow
Inadequate time for patient–doctor interaction

Digital automation supports a more organized, reliable, and high-performance healthcare environment.

What Is Digital Healthcare Automation?

Digital healthcare automation refers to the use of AI, software systems, connected devices, and workflow engines to automate medical and administrative procedures. These tools reduce manual intervention wherever possible and ensure accuracy, repeatability, and continuity.

Core areas of automation include:

Appointment management and scheduling
Electronic medical record updates
Auto-generation of diagnostic summaries
Automated clinical reminders
Medication and health-plan notifications
Remote monitoring and alert systems
Digital report formatting
Workflow optimization for hospital operations

SecondMedic incorporates automation across its telemedicine, diagnostics, monitoring, and preventive-care systems.

Automated Appointment Scheduling and Coordination

Appointment automation is one of the most practical innovations in India’s digital health landscape. Without automation, patients often encounter long queues, missed follow-ups, and scheduling conflicts.

Automated scheduling helps by:

Matching patients to the right doctor
Reducing wait times
Preventing double bookings
Prioritizing urgent cases
Coordinating virtual and in-person consults
Helping doctors manage daily workloads efficiently

SecondMedic’s automated scheduling engine analyzes doctor availability, user urgency, and specialty requirements to optimize appointment flow.

Automation in Diagnostics and Reporting

Medical diagnostics often involve multiple steps that traditionally require human intervention-uploading reports, comparing past results, formatting summaries, highlighting abnormalities, and generating clear interpretations.

Automation enhances diagnostic workflows by:

Auto-organizing digital medical reports
Highlighting abnormal ranges
Identifying missing test values
Summarizing patient history for doctors
Formatting structured reports instantly
Automating comparisons with past results

For AI-based imaging and lab analytics, automation helps radiologists and clinicians detect patterns faster and reduce minor reporting inconsistencies.

Remote Monitoring and Automated Alerts

Remote patient monitoring has grown rapidly in India, especially for chronic diseases. Wearable devices and home-health tools generate continuous data streams. Automation helps turn these raw inputs into actionable insights.

Monitoring automation includes:

Auto-detection of abnormal vitals
Alerts for risky trends
Medication reminders
Follow-up triggers
Predictive alerts using AI
Aggregated health reports for doctors

For chronic care, this ensures timely intervention and reduces emergency visits.

Enhancing Hospital and Clinic Workflows

Healthcare automation in clinical facilities improves operational efficiency and reduces administrative bottlenecks. Hospitals benefit significantly from automated workflows that ensure consistency and speed.

Applications include:

Patient flow management
Automated admission and discharge processes
Digital billing and inventory management
Lab and pharmacy integration
Nursing task automation
Centralized communication dashboards

These improvements reduce patient wait times and improve overall care delivery.

Improving Patient Engagement Through Automation

Automation supports patients by making healthcare more accessible and predictable. Many individuals struggle to remember follow-ups or understand complex medical guidance. Automated systems simplify this journey.

Key patient-facing automation benefits include:

Reminders for medications and appointments
Preventive health notifications
Personalized care tips
AI-driven chat support for common queries
Post-consultation guidance delivery
Automated sharing of doctor notes and reports

SecondMedic uses automation to ensure patients remain engaged throughout their health journey.

Automation and AI: A Powerful Combination

AI enhances healthcare automation by making it adaptive and context-aware. Instead of following fixed rules, AI learns from patterns, outcomes, and user behavior to optimize workflows.

AI strengthens automation through:

Predictive recommendations
Dynamic scheduling adjustments
Automated report summaries
Early detection of errors
Smart escalation of high-risk cases

This combination powers advanced clinical systems that support both providers and patients.

Challenges in Implementing Healthcare Automation in India

Automation requires planning, infrastructure, and careful integration. Key challenges include:

Fragmented patient data across facilities
Infrastructure limitations in rural areas
Varying digital readiness across hospitals
Need for staff training
Ensuring compliance with DPDP and ABDM standards

Despite these challenges, adoption is increasing as digital health becomes mainstream.

The Future of Digital Healthcare Automation in India

India is poised for significant automation growth, driven by advancements in AI, 5G connectivity, cloud platforms, and interoperable health records. Over the next decade, digital healthcare automation will include:

AI-powered hospital command centers
Fully automated radiology and pathology workflows
Robotic process automation (RPA) in administrative processes
Automated care coordination for chronic diseases
Voice-based digital assistants for patient queries
Smart triage algorithms integrated across telemedicine networks
Predictive automation for emergency care

SecondMedic is building a modern digital ecosystem that integrates AI, automation, and predictive healthcare tools, creating a seamless and intelligent healthcare experience for users.

Conclusion

Digital healthcare automation India is unlocking a new era of efficiency, precision, and patient-centered care. By automating clinical workflows, diagnostic tasks, and patient engagement processes, healthcare organizations can deliver faster, more reliable services. Automation supports doctors with real-time insights, reduces administrative burdens, and ensures that patients receive timely interventions.

SecondMedic continues to lead this transformation by integrating automation into virtual care, diagnostics, monitoring, and preventive health solutions, shaping the future of digital healthcare in India.

To access advanced automated digital healthcare tools, visit www.secondmedic.com

References

NITI Aayog – Digital Health India
ABDM – National Digital Health Mission
IMARC – Healthcare Automation Market India
WHO – Digital Health Workflow Automation
FICCI – Hospital Automation India

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.