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Published on: Jul 02, 2021
2 minute read
By: Dr Rakesh Rai

Delta Plus Variant Mystery: What Can Cause The Third Covid Wave?

Delta plus variant mystery: What can cause the third Covid wave?

Things in India are looking to normalize and beginning to reopen after a deadly second wave of Covid-19 infections devastated the country in April and May. There is various thought process from experts who are warning that a third wave could strike in the next few months. The majority of Indians are worried about new variants named delta plus, which is related to the Delta, an existing variant of concern first identified in India last year that was responsible for the deadly second wave.

The million-dollar question is how realistic these fears are. The reality is that future waves are not out of question but their severity and spread depend on several factors. In the past few weeks, the number of average daily cases in India has tapered down to less than 40,000 in recent days which was peak over 420,000 in May. The big drop in numbers has mainly because of strict lockdowns by states.

Many social and political events added to the second wave. If the reopening process are not orchestrated in a controlled fashion the next wave could come sooner than expected.

We are in a very decisive phase and our fate will depend on how we behave. Opening the states in a staggered manner is best. Going aggressive with vaccination and continue with COVID protocols will be the winning strategy. A balanced local and central health protocols could do the magic while severe action on defaulters could be used as a deterrent.

We know that the Delta variant had a killer impact during the second wave. The risk of future mutants in densely populated areas is known and preventive actions should be put in place immediately. There is no clear data around Delta plus but things have changed really fast when the proactive approach is not taken in advance. We need to understand that mutants only emerge when active transmission happening. A lot of research is happening around it take preemptive containment measures by understanding probable sequences.

So far data is indicating that the current vaccine is delivering good results in emerging mutants. India had sequenced 30,000 samples until June, but experts believe more needs to be done because the current vaccine is not a guaranteed long-term solution.

There are multiple cases where vaccinated people have got infected. Some call 3rd wave inevitable and some call it will be a smaller wave but the science is indicating that it will all depend on how effective our existing vaccine is against the new variants.

So, in conclusion, one can say that the key is the vaccinated population in controlling the wave and even allowing it to be formed. The acquired immunity and its efficacy will be crucial in determining the damage the third wave can cause. The required daily dose is upwards of 10 million to get all eligible populations covered by 2021.

The wide range of infection-causing natural antibodies and vaccination combined will provide the ammunition India needs badly to shield against future variants. The problem is the data around it is not very accurate. During the height of infections lot of COVID, infections went unreported. A lot of statisticians around it are guessing the acquired immunity percentage to be around 65%. This number should not be the reason we can take it easy.

Acquired immunity is immunity you develop over time from a vaccine or exposure to the infection.

Conclusively it can be said that “Third wave is only possible if the new variant beats the barriers of acquired immunity.”

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Asthma Symptoms in Adults: Early Signs, Triggers, and When to Seek Care

Asthma is often perceived as a childhood condition, but a significant number of cases develop or persist into adulthood. In India, adult asthma is increasingly recognised due to rising air pollution, occupational exposure and lifestyle-related risk factors. Unfortunately, asthma symptoms in adults are frequently misdiagnosed as recurrent infections, allergies or age-related breathlessness, leading to delayed treatment.

Understanding adult asthma symptoms is critical for early diagnosis, effective control and prevention of severe attacks.

What Is Asthma?

Asthma is a chronic inflammatory disease of the airways. In asthma, the airways become:

inflamed
narrow
overly sensitive to triggers

This leads to difficulty in breathing, especially during exposure to specific stimuli.

Why Adult Asthma Is Often Missed

Adult asthma symptoms may:

appear gradually
vary in severity
mimic common respiratory conditions

According to Indian Council of Medical Research and WHO data, many adults remain undiagnosed for years, increasing the risk of complications.

Common Asthma Symptoms in Adults

Wheezing

A high-pitched whistling sound while breathing, especially during exhalation, is a classic asthma sign.

Shortness of Breath

Adults with asthma often feel:

breathless during routine activities
difficulty taking deep breaths

This may worsen at night or early morning.

Chest Tightness

Many describe a sensation of pressure or tightness in the chest, which can be mistaken for heart-related issues.

Chronic Cough

A persistent cough, especially:

at night
early morning
after exercise

is a common but overlooked asthma symptom.

Symptoms That Worsen With Triggers

Asthma symptoms often intensify after exposure to specific triggers.

Air Pollution and Smoke

Urban pollution, vehicle emissions and indoor smoke significantly worsen asthma symptoms in adults.

Allergens

Dust mites, pollen, mould and pet dander are common triggers.

Respiratory Infections

Viral infections can trigger asthma flare-ups or reveal undiagnosed asthma.

Physical Activity

Exercise-induced asthma causes breathlessness and wheezing during or after physical exertion.

Weather Changes

Cold air, humidity and sudden temperature changes can aggravate symptoms.

Adult-Onset Asthma

Adult-onset asthma differs from childhood asthma.

Characteristics include:

onset after age 20–30
less association with childhood allergies
more persistent symptoms
higher likelihood of severe disease

Occupational exposure and hormonal changes contribute to adult-onset asthma.

Risk Factors for Asthma in Adults

Several factors increase asthma risk:

long-term exposure to pollution
smoking or passive smoking
occupational chemicals or dust
obesity
family history of asthma
chronic sinusitis or allergies

Women may experience asthma onset or worsening during hormonal changes.

When Asthma Symptoms Become Serious

Seek immediate medical attention if experiencing:

severe breathlessness
difficulty speaking in full sentences
bluish lips or fingertips
rapid worsening of symptoms
poor response to usual inhalers

These signs indicate a potentially life-threatening asthma attack.

How Adult Asthma Is Diagnosed

Diagnosis includes:

detailed symptom history
physical examination
lung function tests (spirometry)
response to bronchodilators

Early diagnosis improves long-term outcomes.

Impact of Untreated Asthma

Untreated asthma can lead to:

frequent attacks
reduced lung function
sleep disturbances
missed workdays
reduced quality of life

According to Lancet respiratory studies, uncontrolled asthma increases hospitalisation risk.

Managing Asthma Symptoms in Adults

Effective asthma management focuses on:

identifying and avoiding triggers
using prescribed inhalers correctly
monitoring symptoms regularly
maintaining follow-up care

Asthma action plans help patients recognise worsening symptoms early.

Role of Preventive Healthcare

Preventive healthcare helps:

detect asthma early
assess lung function
guide lifestyle modifications

Regular health checkups are especially important for individuals with respiratory symptoms or occupational exposure.

Lifestyle Measures That Support Asthma Control

Helpful practices include:

avoiding smoking
improving indoor air quality
wearing masks in polluted environments
maintaining healthy weight
regular, moderate exercise

Lifestyle support complements medical treatment.

Mental Health and Asthma

Stress and anxiety can worsen asthma symptoms.

Stress management:

reduces symptom frequency
improves medication response

Holistic care improves asthma outcomes.

Importance of Medication Adherence

Asthma medications work best when:

taken regularly as prescribed
inhaler technique is correct

Skipping treatment increases flare-up risk.

Long-Term Outlook for Adults With Asthma

With proper management:

symptoms are well controlled
severe attacks are preventable
normal activity levels are achievable

Most adults with asthma lead active, productive lives.

Conclusion

Asthma symptoms in adults are often subtle, variable and easily mistaken for common respiratory problems. Wheezing, breathlessness, chest tightness and chronic cough should not be ignored, especially when triggered by pollution, exercise or weather changes. Early diagnosis, trigger control and consistent treatment are essential to prevent severe attacks and preserve lung health. Recognising adult asthma early empowers individuals to manage symptoms effectively and maintain a good quality of life.

References

Indian Council of Medical Research (ICMR) – Respiratory Disease and Asthma Studies
World Health Organization (WHO) – Asthma Management and Prevention Guidelines
National Family Health Survey (NFHS-5) – Respiratory Health Indicators
Lancet Respiratory Medicine – Adult Asthma Outcomes and Management
NITI Aayog – Air Pollution and Respiratory Health Reports
Statista – Global Asthma Prevalence and Trends

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