• Published on: Apr 04, 2020
  • 3 minute read
  • By: Dr Rajan Choudhary

Developing A Vaccine For COVID-19? Part 1

  • WhatsApp share link icon
  • copy & share link icon
  • twitter share link icon
  • facebook share link icon

It is often stated vaccination has made the greatest contribution to global health of any human discovery, other than clean water and sanitation, and their impact on everyday life is immediately evident. We have managed to completely eradicate two major infections from existence (smallpox and rinderpest) , and the WHO are working towards adding polio to that list.

In these cases the numbers speak for themselves. It is estimated that the eradication of smallpox in 1980 has saved 5 million lives per year, adding up to 150 to 200 million by 2018. Common vaccination programmes for polio, measles, mumps, rubella, rabies and hepatitis A have prevented nearly 200 million cases from occurring in the US alone over the past 50 years, and 4.5 billion instances of the diseases worldwide.

We have achieved a 99% immunisation rate against polio, preventing children from suffering crippling paralysis, and only 3 countries remain. Sadly, around 1.4 million children under 5 still die from preventable diseases each year as they do not have access to these life saving vaccines, but charities and public health organisations around the world are working hard to improve access.

So what are vaccines? And how will they help is in the face of the latest pandemic? Here we will go into the challenges behind making vaccines, and why a vaccine against COVID-19 is unlikely to be ready in the next few months, or even this year.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024226/ contribution of vaccination

https://www.who.int/features/factfiles/polio/en/ polio eradication

https://www.sciencedaily.com/releases/2017/03/170303163208.htm study article

WHAT IS A VACCINE

The human body’s immune system is incredibly smart. It is able to distinguish between infective organisms, such as bacteria, viruses and parasites, from our own body’s cells, target these invaders for destruction and keep our bodies healthy. Even better, the body remembers any previous infections it has had before, recognise these previous infections even quicker and even eradicate the disease before we know we are infected.

Vaccines target the immune system’s memory by presenting them with pieces of these infective diseases. The small amounts do not cause any infective symptoms, but if the person is infected later in life their body will mount a quicker response and prevent them from falling ill. These vaccines can contain broken up parts of the organisms, “dead” organisms or “live” versions that have been severely weakened so they cannot cause any harm.

In summary, medicines treat us when we get an infection. Vaccines make sure we never suffer from an infection in the first place.

https://www.chop.edu/centers-programs/vaccine-education-center/making-vaccines/how-are-vaccines-made Making Vaccines

THE HURDLES WE FACE IN RESEARCH

Making a vaccine is a difficult process, one that can take 3–5 years and cost hundreds of millions of dollars, sometimes billions of dollars. This is because there are many difficult steps to be taken in the process of creating a vaccine that is effective, but more importantly one that is safe.

To start with the troubling organism has to be identified. For COVID-19 it took a few weeks to recognise the virus responsible, and some time more to understand its genetic code and grow the virus in lab conditions. We then have to understand the virus, how it infects, how it causes symptoms, and how it has mutated compared to the coronaviruses responsible for SARS and MERS.

After this, we have to isolate parts of the virus our immune system will recognise. This is usually the outside coat of the virus. The DNA responsible for making these parts need to be found in the virus’ genetic code, and put inside other “skeleton” viruses. This will force the dummy virus to look like coronavirus, without the ability to infect and kill someone.

These dummy viruses can be injected into animals to see if it causes an immune reaction, whether the immune system recognises it as the coronavirus responsible for COVID-19, and whether it will protect the animal from the real COVID-19. Up to now the research has likely cost a few million dollars. The next step is when the price inflates up to billions.

If the vaccine appears safe in animals, it can be tested in humans. This can be dangerous at first, since we don’t know whether a vaccine that works in an animal will work in a human. And we don’t know if there will be any side effects to the vaccine. Human testing has to be very thorough, very careful, and safe for use. If you give too much of the virus it might make the person sick, too little and it wont immunise the person. These clinical trials can take years, and if the vaccine fails at this point its back to the drawing board, to try another step.

https://www.theatlantic.com/politics/archive/2014/10/how-to-make-an-ebola-vaccine-5-simplified-steps/454443/ ebola vaccine

Now we have a basic understanding of what vaccines are and why it takes so long to make a vaccine. In the next part we will look at why viral vaccines can cause even more problems, and how far we have come with the COVID-19 vaccine,

Dr Rajan Choudhary, London UK

Read Blog
Kindness Week encourages

Kindness Week – Recognize Employees Going the Extra Mile

In today’s fast-paced corporate world, deadlines, targets and performance metrics often dominate workplace conversations. However, one powerful factor that consistently drives employee satisfaction and productivity is kindness.

Kindness Week is a meaningful initiative designed to celebrate employees who go beyond their defined roles, support their colleagues and contribute positively to workplace culture. Recognizing those who consistently go the extra mile not only boosts morale but also strengthens organizational values.

 

Why Kindness Matters in the Workplace

Kindness in professional settings includes:

  • Offering help without being asked
     

  • Supporting team members during stressful periods
     

  • Maintaining respectful communication
     

  • Appreciating others’ contributions
     

  • Showing empathy during challenges
     

These small actions significantly influence employee wellbeing and workplace harmony.

Research in organizational psychology indicates that workplaces with higher levels of appreciation and positive reinforcement experience:

  • Better employee engagement
     

  • Lower stress levels
     

  • Higher productivity
     

  • Improved retention rates
     

 

The Purpose of Kindness Week

Kindness Week serves multiple objectives:

1. Encourage Positive Behavior

By highlighting positive actions, organizations reinforce desirable behaviors.

2. Promote Appreciation

Employees feel valued when their efforts are acknowledged publicly.

3. Strengthen Team Bonds

Recognition fosters collaboration and trust.

4. Improve Workplace Morale

Celebrating contributions creates a supportive environment.

 

Benefits of Recognizing Employees Who Go the Extra Mile

Boosted Motivation

When employees know their efforts are noticed, they are more motivated to maintain high performance.

Increased Engagement

Recognition creates emotional connection with the organization.

Better Mental Wellbeing

Feeling appreciated reduces stress and burnout.

Enhanced Organizational Reputation

A positive work culture attracts talent and strengthens employer branding.

 

How to Celebrate Kindness Week

1. Employee Appreciation Awards

Create categories such as:

  • Kindness Champion
     

  • Team Support Star
     

  • Helping Hand Award
     

  • Positive Attitude Leader
     

Keep criteria transparent and inclusive.

 

2. Gratitude Wall

Encourage employees to post thank-you notes recognizing colleagues’ contributions.

This creates visible appreciation within the organization.

 

3. Leadership Acknowledgment

Managers and senior leaders can personally recognize employees during team meetings.

Direct appreciation from leadership increases impact.

 

4. Team Lunch or Wellness Event

Organize:

  • Welcome lunches
     

  • Healthy snack days
     

  • Mindfulness sessions
     

  • Team-building activities
     

Combining kindness with wellness initiatives reinforces healthy workplace culture.

 

5. Random Acts of Kindness Challenge

Encourage employees to perform small acts such as:

  • Mentoring a junior colleague
     

  • Helping with workload
     

  • Writing appreciation emails
     

  • Sharing learning resources
     

Recognize participation at week’s end.

 

Kindness and Employee Retention

Studies consistently show that employees who feel recognized are more likely to remain loyal to their organizations.

Recognition contributes to:

  • Reduced turnover
     

  • Improved job satisfaction
     

  • Stronger commitment
     

  • Positive organizational citizenship behavior
     

Kindness Week may seem simple, but its long-term cultural impact can be significant.

 

Promoting Inclusivity During Kindness Week

Ensure recognition initiatives:

  • Avoid favoritism
     

  • Include all departments
     

  • Value non-managerial roles equally
     

  • Recognize behind-the-scenes contributions
     

Inclusivity strengthens fairness and trust.

 

Measuring the Impact

Organizations can assess the success of Kindness Week by tracking:

  • Employee feedback surveys
     

  • Participation rates
     

  • Team engagement metrics
     

  • Retention trends
     

Continuous appreciation initiatives beyond one week create sustainable results.

 

Building a Culture Beyond One Week

Kindness should not be limited to a single event. Companies can maintain momentum by:

  • Monthly recognition programs
     

  • Peer-to-peer appreciation platforms
     

  • Wellness check-ins
     

  • Leadership mentoring initiatives
     

Embedding appreciation into daily operations ensures lasting cultural transformation.

 

The Indian Corporate Context

In India’s rapidly growing corporate landscape, workplace stress and competition are increasing. Initiatives like Kindness Week support mental wellbeing, collaboration and emotional resilience.

Organizations prioritizing empathy and recognition often witness stronger teamwork and healthier work environments.

 

Conclusion

Kindness Week is more than a celebration — it is a strategic initiative to recognize employees who go the extra mile and foster a culture of appreciation. By encouraging empathy, gratitude and recognition, organizations create an environment where employees feel valued and motivated.

Simple acts of appreciation can lead to stronger teams, improved morale and long-term success. Recognizing kindness today builds a more collaborative and positive workplace for tomorrow.

 

References

  • Society for Human Resource Management – Employee Recognition Studies
  • Indian Journal of Occupational Health – Workplace Wellbeing Research
  • Harvard Business Review – Impact of Appreciation on Productivity
  • World Health Organization – Healthy Workplace Framework
  • National Institute of Mental Health – Workplace Mental Health Insights

See all

Live Doctor consultation
Live Doctor Chat

Download Our App & Get Consultation from anywhere.

App Download
call icon for mobile number calling and whatsapp at secondmedic