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Published on: Apr 04, 2020
3 minute read
By: Dr Rajan Choudhary

Developing A Vaccine For COVID-19? Part 1

It is often stated vaccination has made the greatest contribution to global health of any human discovery, other than clean water and sanitation, and their impact on everyday life is immediately evident. We have managed to completely eradicate two major infections from existence (smallpox and rinderpest) , and the WHO are working towards adding polio to that list.

In these cases the numbers speak for themselves. It is estimated that the eradication of smallpox in 1980 has saved 5 million lives per year, adding up to 150 to 200 million by 2018. Common vaccination programmes for polio, measles, mumps, rubella, rabies and hepatitis A have prevented nearly 200 million cases from occurring in the US alone over the past 50 years, and 4.5 billion instances of the diseases worldwide.

We have achieved a 99% immunisation rate against polio, preventing children from suffering crippling paralysis, and only 3 countries remain. Sadly, around 1.4 million children under 5 still die from preventable diseases each year as they do not have access to these life saving vaccines, but charities and public health organisations around the world are working hard to improve access.

So what are vaccines? And how will they help is in the face of the latest pandemic? Here we will go into the challenges behind making vaccines, and why a vaccine against COVID-19 is unlikely to be ready in the next few months, or even this year.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024226/ contribution of vaccination

https://www.who.int/features/factfiles/polio/en/ polio eradication

https://www.sciencedaily.com/releases/2017/03/170303163208.htm study article

WHAT IS A VACCINE

The human body’s immune system is incredibly smart. It is able to distinguish between infective organisms, such as bacteria, viruses and parasites, from our own body’s cells, target these invaders for destruction and keep our bodies healthy. Even better, the body remembers any previous infections it has had before, recognise these previous infections even quicker and even eradicate the disease before we know we are infected.

Vaccines target the immune system’s memory by presenting them with pieces of these infective diseases. The small amounts do not cause any infective symptoms, but if the person is infected later in life their body will mount a quicker response and prevent them from falling ill. These vaccines can contain broken up parts of the organisms, “dead” organisms or “live” versions that have been severely weakened so they cannot cause any harm.

In summary, medicines treat us when we get an infection. Vaccines make sure we never suffer from an infection in the first place.

https://www.chop.edu/centers-programs/vaccine-education-center/making-vaccines/how-are-vaccines-made Making Vaccines

THE HURDLES WE FACE IN RESEARCH

Making a vaccine is a difficult process, one that can take 3–5 years and cost hundreds of millions of dollars, sometimes billions of dollars. This is because there are many difficult steps to be taken in the process of creating a vaccine that is effective, but more importantly one that is safe.

To start with the troubling organism has to be identified. For COVID-19 it took a few weeks to recognise the virus responsible, and some time more to understand its genetic code and grow the virus in lab conditions. We then have to understand the virus, how it infects, how it causes symptoms, and how it has mutated compared to the coronaviruses responsible for SARS and MERS.

After this, we have to isolate parts of the virus our immune system will recognise. This is usually the outside coat of the virus. The DNA responsible for making these parts need to be found in the virus’ genetic code, and put inside other “skeleton” viruses. This will force the dummy virus to look like coronavirus, without the ability to infect and kill someone.

These dummy viruses can be injected into animals to see if it causes an immune reaction, whether the immune system recognises it as the coronavirus responsible for COVID-19, and whether it will protect the animal from the real COVID-19. Up to now the research has likely cost a few million dollars. The next step is when the price inflates up to billions.

If the vaccine appears safe in animals, it can be tested in humans. This can be dangerous at first, since we don’t know whether a vaccine that works in an animal will work in a human. And we don’t know if there will be any side effects to the vaccine. Human testing has to be very thorough, very careful, and safe for use. If you give too much of the virus it might make the person sick, too little and it wont immunise the person. These clinical trials can take years, and if the vaccine fails at this point its back to the drawing board, to try another step.

https://www.theatlantic.com/politics/archive/2014/10/how-to-make-an-ebola-vaccine-5-simplified-steps/454443/ ebola vaccine

Now we have a basic understanding of what vaccines are and why it takes so long to make a vaccine. In the next part we will look at why viral vaccines can cause even more problems, and how far we have come with the COVID-19 vaccine,

Dr Rajan Choudhary, London UK

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Community Health Wellness Programs: Building Healthier Communities Together

Healthcare does not begin in hospitals—it begins within communities. Community health wellness programs play a vital role in strengthening preventive healthcare systems, improving early detection and reducing disease burden. In India, where both urban and rural populations face increasing lifestyle and infectious disease risks, community-level initiatives are essential.

According to the World Health Organization, preventive and primary healthcare services delivered at community level significantly reduce morbidity and mortality. Indian Council of Medical Research (ICMR) reports also highlight the rising burden of non-communicable diseases such as diabetes and hypertension, emphasizing the need for community-based interventions.

What Are Community Health Wellness Programs?

Community health wellness programs are organized efforts designed to:

promote preventive healthcare
increase health awareness
provide screening services
encourage healthy lifestyle adoption

These programs may be conducted by healthcare organizations, NGOs, corporate CSR initiatives or government agencies.

Why Community Programs Matter in India

India’s healthcare challenges include:

high population density
urban-rural disparities
limited early screening access
rising lifestyle diseases

NFHS-5 data shows increasing prevalence of hypertension, diabetes and obesity, especially in urban areas. Community-level screening improves early detection.

Key Components of Community Health Wellness Programs

1. Preventive Health Screening

Health camps often provide:

blood pressure checks
blood sugar testing
cholesterol screening
BMI measurement

Early detection prevents complications.

2. Health Education and Awareness

Workshops on:

balanced nutrition
physical activity
tobacco cessation
mental health

help individuals adopt healthier habits.

3. Vaccination Drives

Immunization programs reduce spread of infectious diseases.

Community outreach increases coverage.

4. Maternal and Child Health Services

Programs focus on:

prenatal care
nutrition guidance
child immunization

Protecting vulnerable populations strengthens long-term health.

5. Chronic Disease Management Support

Community programs support patients with:

diabetes
hypertension
asthma

Education improves medication adherence.

Benefits of Community Health Wellness Programs

Improved Early Detection

Screening identifies disease before symptoms worsen.

Reduced Healthcare Costs

Preventive care is more affordable than emergency treatment.

Increased Public Awareness

Educated communities make informed health decisions.

Better Access for Underserved Populations

Rural and low-income groups benefit significantly.

Strengthened Public Health Systems

Community-level intervention reduces burden on tertiary hospitals.

Role of Technology in Community Health

Digital health platforms enable:

teleconsultations
electronic health records
AI-assisted risk assessment

Technology improves efficiency and outreach.

Corporate and CSR Involvement

Many organizations integrate community health programs into CSR initiatives.

Such programs:

enhance brand reputation
promote employee engagement
contribute to social impact

Corporate-community partnerships amplify reach.

Addressing Urban Health Challenges

Urban populations face:

pollution exposure
sedentary lifestyles
high stress

Community programs provide screening and awareness to mitigate risk.

Addressing Rural Health Gaps

Rural areas may lack access to:

specialists
diagnostic services
preventive screening

Mobile health camps bridge this gap.

Measuring Impact

Successful programs track:

number of screenings conducted
disease detection rates
follow-up adherence
reduction in risk factors

Data-driven evaluation improves sustainability.

Long-Term Impact on Public Health

Community health wellness programs contribute to:

reduced chronic disease burden
improved life expectancy
stronger healthcare infrastructure

Preventive care at grassroots level creates systemic improvement.

Challenges in Implementation

Common challenges include:

limited funding
awareness barriers
logistical constraints

Collaboration between government, private sector and NGOs improves scalability.

The Future of Community Wellness in India

With rising lifestyle diseases and growing awareness, community wellness initiatives will become central to public health strategy.

Integration of digital tools, preventive screenings and education campaigns will enhance impact.

Conclusion

Community health wellness programs are essential for building resilient and healthier societies. By promoting preventive care, early screening and health education, these initiatives reduce disease burden and improve quality of life. In India’s diverse and rapidly evolving healthcare landscape, community-based wellness efforts serve as a foundation for sustainable public health progress. Investing in community health today ensures stronger, healthier generations tomorrow.

References

World Health Organization (WHO) – Community Health and Preventive Care Reports
Indian Council of Medical Research (ICMR) – Non-Communicable Disease Data
National Family Health Survey (NFHS-5) – Public Health Statistics
NITI Aayog – Primary and Preventive Healthcare Strategy
Lancet – Public Health and Community Intervention Research

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