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Published on: Jul 17, 2020
2 minute read
By: Dr Rajan Choudhary

MRNA Vaccine Against SARS CoV2

An mRNA Vaccine against SARS CoV2

We have previously discussed vaccines against SARS-CoV-2, the virus responsible for COVID-19. On the 14th of July, a preliminary study was published in the New England Journal of Medicine, an internationally reputable medical journal. This study looks at mRNA vaccines in Phase 1 human clinical trials, a first for the virus. Here we will discuss what this means and the results of the study.

mRNA vaccine

Vaccines target the immune system’s memory by presenting them with pieces of these infective diseases. The small amounts do not cause any infective symptoms, but if the person is infected later in life their body will mount a quicker response and prevent them from falling ill. These vaccines can contain broken up parts of the organisms, “dead” organisms or “live” versions that have been severely weakened so they cannot cause any harm.

In 2018 a new type of vaccine was described. Instead of using pre-made protein markers that identify infectious organisms, mRNA vaccines contain genetic material with instructions to produce these markers. Once injected, the person’s cells use these instructions to produce copies of these protein markers. These markers are displayed on the surface of the cell, which in turn is recognized by the immune system, initiating an immune response and producing protective antibodies.

BENEFITS

A major advantage of RNA vaccines is the ease by which they can be made in a laboratory from a DNA template. During a pandemic, this would result in a rapid response and vaccine against a new disease. Conventional vaccines require the use of chicken eggs or cells to produce the vaccines, which can be expensive and time-consuming. These vaccines can be delivered via injections into the skin, blood, muscle, or organs, needle-free into the skin, or via nasal spray. Because these vaccines are so new, we still do not know the best way to deliver it.

Because these vaccines are not made with parts of infective organisms or from live organisms, they are not infectious and will not cause harm through a strong immune response to the vaccine itself, or by causing the disease they aim to vaccinate against. They also appear to be very efficient at generating a reliable immune response to produce antibodies and are well tolerated with few side effects.

NEEDS IMPROVEMENT

Because these types of vaccines are so new there is still a lot we do not understand about them. They may cause unintended effects that we have not yet encountered in human clinical studies. These vaccines also need to be frozen or refrigerated, and so would not be suitable for countries with limited or no refrigeration facilities.

COVID

The SARS-CoV-2 mRNA vaccine codes for one of the virus’ surface spike proteins, responsible for recognizing target cells and fusing the virus into the cell for entry and infection. It was previously recognized as a target for the SARS and MERS viruses.

45 participants received 2 intramuscular injections 28 days apart. None of the participants had any serious side effects after the first injection, or any side effects significant enough to stop the trial. Many had minor to moderate side effects after their second injection (such as fatigue, chills, headache, myalgia, and pain at the injection site), and half the participants taking high dose vaccines had febrile side effects. Overall the side effects were rated as acceptable.

Prior to the vaccine trials, none of the participants had any antibodies against COVID, or any capacity to stop a COIVD infection. After the injections, all participants had noticeable increases in antibodies produced, measurable in their blood. After 43 days, the participant's blood had enough antibodies to reduce infection by SARS-CoV-2 by over 80%.

What is the takeaway? The vaccine is capable of producing an adequate response to protect the vaccine recipient without eliciting any major side effects. These results will be used in phase 2 clinical trials (enrolment began in May) and a phase 3 trial in July 2020. Essentially this means further human trials to further look for side effects in a larger number of volunteers with a more diverse health profile.

This represents an interesting development in producing a rapid vaccine against a new virus responsible for a world-changing pandemic. This new type of vaccine may be the future of vaccines for a broader range of viruses, bacteria, and even cancers.

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Desk Plants Distribution Drive: Improving Mental Health and Workplace decor

Workplace wellness is no longer limited to health checkups and fitness programs. Modern organisations are recognising that mental wellbeing, emotional balance and the physical environment play an equally important role in employee health. One initiative that effectively addresses all three is the Desk Plants Distribution Drive.

Introducing greenery into everyday workspaces is a low-cost, high-impact strategy that improves mental health while enhancing office décor and employee satisfaction.

Why Mental Health Needs Everyday Support at Work

Employees today face:

prolonged screen exposure
high work pressure
sedentary routines
constant digital connectivity

According to World Health Organization and Indian workplace health data, chronic stress and burnout are rising across industries. Small environmental interventions can significantly reduce daily stress and mental fatigue.

What Is a Desk Plants Distribution Drive?

A Desk Plants Distribution Drive involves distributing small, easy-to-maintain plants to employees for placement on their desks or workstations.

These drives are typically:

organisation-wide
part of wellness or engagement programs
aligned with sustainability initiatives

Common desk plants include succulents, pothos, snake plants and peace lilies.

How Desk Plants Improve Mental Health

Stress Reduction

Natural elements have a calming effect on the brain. Studies in occupational psychology show that the presence of plants reduces stress hormone levels and promotes relaxation.

Employees surrounded by greenery report feeling calmer and less overwhelmed during the workday.

Improved Mood and Emotional Balance

Green environments stimulate positive emotional responses. Desk plants help:

reduce irritability
improve mood
create a sense of comfort and wellbeing

This supports emotional resilience at work.

Impact on Focus and Cognitive Performance

Mental fatigue is a major contributor to reduced productivity.

Desk plants help by:

improving concentration
reducing attention fatigue
enhancing creativity

Research published in workplace wellbeing studies indicates that even small amounts of greenery improve cognitive performance.

Enhancing Workplace Décor and Atmosphere

Visual Comfort

Plants soften rigid office interiors, making workspaces feel more welcoming and less clinical.

Personalised Workspaces

Desk plants allow employees to personalise their environment, increasing ownership and job satisfaction.

Improved Indoor Environment

Some plants help reduce indoor pollutants and contribute to a fresher workspace experience.

Desk Plants and Emotional Connection to Workspaces

Having a living element at the desk fosters:

mindfulness
responsibility
emotional attachment to the workspace

These subtle psychological effects support long-term engagement.

Why Desk Plant Drives Work Well in Corporate Wellness Programs

Desk plant initiatives are:

easy to implement
budget-friendly
scalable across teams
inclusive for all roles

They create visible, daily reminders of organisational commitment to employee wellbeing.

Sustainability and CSR Alignment

A Desk Plants Distribution Drive supports:

environmental responsibility
green workplace practices
sustainability goals

It reflects a balanced approach to people and planet wellbeing.

Choosing the Right Plants for Offices

Ideal desk plants should be:

low maintenance
tolerant of indoor lighting
compact and non-intrusive
safe for shared environments

Providing simple care guidelines ensures long-term success.

Employee Engagement Through Green Initiatives

These drives encourage:

shared participation
wellness conversations
positive social interaction

They strengthen workplace culture without disrupting work routines.

Measuring the Impact of Desk Plant Initiatives

Organisations can assess impact through:

employee feedback surveys
stress and engagement indicators
workspace satisfaction scores

According to EY-FICCI workplace wellness reports, environmental wellness initiatives contribute to sustained engagement.

Long-Term Benefits for Organisations

Consistent green initiatives are linked to:

reduced burnout
improved morale
better employee retention
stronger employer branding

Small environmental changes create long-lasting wellness benefits.

Desk Plants as a Gateway to Holistic Wellness

Desk plant drives often lead to:

increased interest in mental health programs
mindfulness and stress management initiatives
ergonomic and workspace improvements

They act as a foundation for broader wellness strategies.

Why Simplicity Matters in Wellness Programs

Complex programs often fail due to low participation.

Desk plant initiatives succeed because they:

integrate naturally into daily life
require minimal effort
deliver visible benefits

Simplicity ensures sustainability.

Conclusion

A Desk Plants Distribution Drive is a powerful yet simple workplace wellness initiative that improves mental health and enhances office décor. By introducing greenery into daily work environments, organisations create calmer, more engaging and emotionally supportive spaces. These initiatives demonstrate that employee wellbeing is influenced not only by policies and programs but also by the environments in which people work. Small green changes can make a meaningful difference to mental wellbeing, productivity and workplace culture.

References

World Health Organization (WHO) – Workplace Mental Health and Environmental Design
Indian Council of Medical Research (ICMR) – Mental Health and Lifestyle Studies
Lancet – Nature Exposure and Psychological Wellbeing Research
NITI Aayog – Workplace Wellness and Mental Health Reports
EY-FICCI – Corporate Wellness and Employee Engagement Studies
Statista – Workplace Wellness and Environmental Design Trends

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