Call
+918447748545

Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

Read Blog

Zincovit Tablets: Uses, Benefits, Dosage, and Side Effects Explained

Nutritional deficiencies are common in India due to irregular diets, stress, fast-paced lifestyles and increased health demands. Multivitamin supplements are often recommended to support overall health, immunity and energy levels. One commonly prescribed supplement is Zincovit tablets.

This comprehensive guide explains what Zincovit is, its uses, benefits, dosage recommendations and potential side effects.

What Are Zincovit Tablets?

Zincovit is a multivitamin and multimineral supplement that contains:

Zinc
Vitamin C
B-complex vitamins
Vitamin A
Vitamin D
Vitamin E
Selenium and other antioxidants

It is commonly prescribed to address nutritional deficiencies and support immune function.

Uses of Zincovit Tablets

Zincovit may be recommended for:

1. Nutritional Deficiencies

Helps replenish low vitamin and mineral levels due to poor diet or illness.

2. Weak Immunity

Zinc and vitamin C support immune system function.

3. Recovery After Illness

Often prescribed during recovery from infections, surgery or prolonged weakness.

4. Fatigue and Low Energy

B vitamins help improve energy metabolism.

5. Hair and Skin Health

Zinc and antioxidants may support healthy skin and hair.

Benefits of Zincovit Tablets

Immune Support

Zinc plays a vital role in immune cell function.

Antioxidant Protection

Vitamins C and E help reduce oxidative stress.

Improved Energy Levels

B-complex vitamins aid in converting food into energy.

Better Nutritional Balance

Supports individuals with dietary gaps.

Support During Stress

Stress can deplete nutrients; supplementation may help maintain balance.

Recommended Dosage

Adults: Usually one tablet daily after meals
Children: Only if prescribed by a pediatrician
Duration: As advised by healthcare professional

Do not exceed recommended dosage without medical guidance.

How to Take Zincovit

Take after food to prevent stomach irritation
Swallow whole with water
Avoid taking with high-calcium foods unless advised

Consistency improves effectiveness.

Possible Side Effects

Zincovit is generally well tolerated. However, some individuals may experience:

Nausea
Mild stomach discomfort
Metallic taste
Constipation or diarrhea (rare)

Severe allergic reactions are uncommon but require immediate medical attention.

Who Should Use Caution?

Consult a doctor before taking Zincovit if you have:

Kidney disorders
Liver disease
Thyroid problems
Known allergies to supplement components

Pregnant and breastfeeding women should seek medical advice before use.

Can Zincovit Be Taken Long-Term?

Short-term use for deficiency correction is common. Long-term use should be monitored by a healthcare provider to avoid excessive intake of certain vitamins or minerals.

Excess zinc intake may interfere with copper absorption if taken excessively over time.

Zincovit and Immunity in India

With increasing concern about immunity and viral infections, supplements containing zinc and antioxidants have gained popularity. However, supplements should complement — not replace — a balanced diet rich in:

Fruits
Vegetables
Whole grains
Protein sources

Healthy lifestyle habits remain essential.

When to Consult a Doctor

Seek medical advice if you experience:

Persistent fatigue
Recurrent infections
Unexplained weight loss
Severe weakness

These may indicate underlying medical conditions beyond nutritional deficiency.

Balanced Nutrition Still Matters

Supplements cannot substitute a healthy diet. Combine Zincovit with:

Proper hydration
Regular exercise
Adequate sleep
Stress management

This ensures overall wellness.

Conclusion

Zincovit tablets are widely used multivitamin supplements that support immunity, energy levels and overall nutritional balance. When taken in recommended doses, they are generally safe and beneficial for individuals with dietary deficiencies or increased nutritional needs.

However, supplements should be used responsibly and under medical guidance, especially for long-term use. Maintaining a healthy diet and lifestyle remains the foundation of good health.

If you are unsure whether Zincovit is right for you, consult a healthcare professional for personalized advice.

References

Indian Council of Medical Research – Nutrient Guidelines
World Health Organization – Micronutrient Recommendations
National Health Portal India – Supplement Safety
Journal of Clinical Nutrition – Zinc and Immunity Studies
National Institute of Nutrition India – Dietary Guidelines

Request A Callback

+91

By using this website/app, I confirm that I am at least 18 years old and consent to the processing of my personal data in accordance with the Terms of Service, Privacy Policy, and Declaration.