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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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Switch Soda with Detox Water: A Simple Step Toward Better Metabolic Health

Soda and sugary beverages have become a major contributor to India’s rising burden of metabolic diseases. According to NFHS-5 and ICMR data, high intake of sugary drinks significantly increases the risk of obesity, high blood sugar, fatty liver disease and heart problems. Replacing these drinks with detox water is one of the easiest and most sustainable lifestyle changes for preventive health.

Detox water is not a medical treatment-it is a healthy hydration alternative that supports the body’s natural processes. SecondMedic encourages simple, evidence-based swaps like this to help individuals improve daily habits without drastic diets.

Why Soda Is a Major Health Concern in India

1. Extremely high sugar content

A single can of soda contains:

8-10 teaspoons of sugar
Over 140 empty calories

This spikes glucose levels and increases insulin resistance.

2. Artificial additives

Flavours, colours and preservatives strain the liver and may worsen inflammation.

3. Link to chronic diseases

ICMR and Lancet studies show soda consumption increases risk of:

Type 2 diabetes
Hypertension
Weight gain
Non-alcoholic fatty liver disease (NAFLD)

4. Poor hydration

Soda does not hydrate the body. Caffeine and sugar can actually increase dehydration.

Benefits of Switching to Detox Water

Detox water provides hydration and additional wellness support through natural ingredients.

• Improved metabolism

Ingredients like lemon, ginger and cinnamon support metabolic balance.

• Better digestion

Mint and ginger soothe the digestive system.

• Stable blood sugar

Sugar-free detox blends prevent rapid glucose spikes.

• Enhanced hydration

Water absorption improves when infused with electrolytes and antioxidants.

• Reduced cravings

Replacing soda breaks dependence on sugar.

• Skin health improvement

Hydration + antioxidants help reduce dullness and inflammation.

Popular Detox Water Ingredients and Their Benefits

Lemon

Rich in vitamin C and antioxidants, helps improve digestion and immunity.

Mint

Reduces bloating and supports gut comfort.

Cucumber

Hydrates deeply and reduces water retention.

Cinnamon

Known for supporting stable blood sugar.

Ginger

Anti-inflammatory and excellent for digestion.

Apple slices

Add natural sweetness without added sugar.

Berries

High in antioxidants; good for heart health.

Easy Detox Water Recipes

1. Lemon + Ginger Detox

Supports metabolic health and digestion.

2. Cucumber + Mint Hydration Blend

Great for daily hydration and cooling.

3. Apple + Cinnamon Water

Helps stabilise glucose naturally.

4. Mixed Berry Infused Water

Boosts antioxidant levels for skin and heart health.

5. Turmeric + Lemon Detox

Mild anti-inflammatory properties.

How Detox Water Helps Reduce Soda Dependence

1. Replaces sweetness gradually

Natural fruit flavours reduce the urge for sugary beverages.

2. Keeps you full

Hydration decreases cravings, especially in the evening.

3. Offers variety

Different combinations keep the habit interesting.

4. Improves energy

Consistent hydration reduces fatigue and brain fog.

The Science Behind Hydration and Metabolic Health

According to WHO and NITI Aayog health reports:

Hydration improves nutrient transport
Helps maintain blood pressure
Aids liver detoxification
Supports kidney function

Soda disrupts these processes, while detox water supports them.

How SecondMedic Helps You Transition from Soda to Healthy Hydration

• AI Health Guide

Identifies sugar consumption patterns and suggests healthier beverage alternatives.

• Dietitian support

Provides personalised hydration plans for metabolic health.

• Preventive care tracking

Monitors progress for weight, energy and blood sugar.

• Health education

SecondMedic guides families, teenagers and adults on sustainable lifestyle swaps.

Tips to Make the Switch Successfully

1. Start gradually

Replace one soda per day with detox water.

2. Add natural flavour

Use citrus or herbs to enhance taste.

3. Keep it accessible

Carry a bottle to avoid impulse soda purchases.

4. Choose chilled detox water

Cold drinks create a similar refreshing experience.

5. Track your progress

Energy and digestion improve noticeably within 2-3 weeks.

Conclusion

Switching soda with detox water is a small step with big preventive health benefits. It reduces sugar intake, supports metabolic wellness, improves hydration and strengthens long-term health. With personalized recommendations from SecondMedic, this transition becomes easy, enjoyable and effective.

References

• ICMR - Sugar Consumption & Metabolic Health Report
• NFHS-5 - Obesity, Diet and Lifestyle Indicators
• NITI Aayog - Preventive Health & Hydration Behaviour Study
• WHO - Health Effects of Sugary Drinks
• Lancet - Soda Consumption & Disease Burden India
• Statista - Beverage Consumption Trends in India
• EY-FICCI - Lifestyle Behaviour & Preventive Health Report

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