• Published on: May 31, 2021
  • 1 minute read
  • By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail" 

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REGN-COV2 – Artificial "antibody cocktail" 

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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Kindness Week encourages

Kindness Week – Recognize Employees Going the Extra Mile

In today’s fast-paced corporate world, deadlines, targets and performance metrics often dominate workplace conversations. However, one powerful factor that consistently drives employee satisfaction and productivity is kindness.

Kindness Week is a meaningful initiative designed to celebrate employees who go beyond their defined roles, support their colleagues and contribute positively to workplace culture. Recognizing those who consistently go the extra mile not only boosts morale but also strengthens organizational values.

 

Why Kindness Matters in the Workplace

Kindness in professional settings includes:

  • Offering help without being asked
     

  • Supporting team members during stressful periods
     

  • Maintaining respectful communication
     

  • Appreciating others’ contributions
     

  • Showing empathy during challenges
     

These small actions significantly influence employee wellbeing and workplace harmony.

Research in organizational psychology indicates that workplaces with higher levels of appreciation and positive reinforcement experience:

  • Better employee engagement
     

  • Lower stress levels
     

  • Higher productivity
     

  • Improved retention rates
     

 

The Purpose of Kindness Week

Kindness Week serves multiple objectives:

1. Encourage Positive Behavior

By highlighting positive actions, organizations reinforce desirable behaviors.

2. Promote Appreciation

Employees feel valued when their efforts are acknowledged publicly.

3. Strengthen Team Bonds

Recognition fosters collaboration and trust.

4. Improve Workplace Morale

Celebrating contributions creates a supportive environment.

 

Benefits of Recognizing Employees Who Go the Extra Mile

Boosted Motivation

When employees know their efforts are noticed, they are more motivated to maintain high performance.

Increased Engagement

Recognition creates emotional connection with the organization.

Better Mental Wellbeing

Feeling appreciated reduces stress and burnout.

Enhanced Organizational Reputation

A positive work culture attracts talent and strengthens employer branding.

 

How to Celebrate Kindness Week

1. Employee Appreciation Awards

Create categories such as:

  • Kindness Champion
     

  • Team Support Star
     

  • Helping Hand Award
     

  • Positive Attitude Leader
     

Keep criteria transparent and inclusive.

 

2. Gratitude Wall

Encourage employees to post thank-you notes recognizing colleagues’ contributions.

This creates visible appreciation within the organization.

 

3. Leadership Acknowledgment

Managers and senior leaders can personally recognize employees during team meetings.

Direct appreciation from leadership increases impact.

 

4. Team Lunch or Wellness Event

Organize:

  • Welcome lunches
     

  • Healthy snack days
     

  • Mindfulness sessions
     

  • Team-building activities
     

Combining kindness with wellness initiatives reinforces healthy workplace culture.

 

5. Random Acts of Kindness Challenge

Encourage employees to perform small acts such as:

  • Mentoring a junior colleague
     

  • Helping with workload
     

  • Writing appreciation emails
     

  • Sharing learning resources
     

Recognize participation at week’s end.

 

Kindness and Employee Retention

Studies consistently show that employees who feel recognized are more likely to remain loyal to their organizations.

Recognition contributes to:

  • Reduced turnover
     

  • Improved job satisfaction
     

  • Stronger commitment
     

  • Positive organizational citizenship behavior
     

Kindness Week may seem simple, but its long-term cultural impact can be significant.

 

Promoting Inclusivity During Kindness Week

Ensure recognition initiatives:

  • Avoid favoritism
     

  • Include all departments
     

  • Value non-managerial roles equally
     

  • Recognize behind-the-scenes contributions
     

Inclusivity strengthens fairness and trust.

 

Measuring the Impact

Organizations can assess the success of Kindness Week by tracking:

  • Employee feedback surveys
     

  • Participation rates
     

  • Team engagement metrics
     

  • Retention trends
     

Continuous appreciation initiatives beyond one week create sustainable results.

 

Building a Culture Beyond One Week

Kindness should not be limited to a single event. Companies can maintain momentum by:

  • Monthly recognition programs
     

  • Peer-to-peer appreciation platforms
     

  • Wellness check-ins
     

  • Leadership mentoring initiatives
     

Embedding appreciation into daily operations ensures lasting cultural transformation.

 

The Indian Corporate Context

In India’s rapidly growing corporate landscape, workplace stress and competition are increasing. Initiatives like Kindness Week support mental wellbeing, collaboration and emotional resilience.

Organizations prioritizing empathy and recognition often witness stronger teamwork and healthier work environments.

 

Conclusion

Kindness Week is more than a celebration — it is a strategic initiative to recognize employees who go the extra mile and foster a culture of appreciation. By encouraging empathy, gratitude and recognition, organizations create an environment where employees feel valued and motivated.

Simple acts of appreciation can lead to stronger teams, improved morale and long-term success. Recognizing kindness today builds a more collaborative and positive workplace for tomorrow.

 

References

  • Society for Human Resource Management – Employee Recognition Studies
  • Indian Journal of Occupational Health – Workplace Wellbeing Research
  • Harvard Business Review – Impact of Appreciation on Productivity
  • World Health Organization – Healthy Workplace Framework
  • National Institute of Mental Health – Workplace Mental Health Insights

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