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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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AI-Powered Healthy Cookbook: India’s New Way to Eat Smarter and Live Healthier

Healthy eating in India is rapidly evolving. With rising lifestyle diseases, increasing digital adoption, and growing awareness of nutrition science, people are prioritizing what they eat more than ever before. However, the challenge remains-most people don't know what to cook, how to plan meals, or which foods match their personal health needs.

This is where the AI-Powered Healthy Cookbook becomes a game changer.

SecondMedic’s AI-driven nutrition engine blends medical science with intelligent recipe planning to help Indians eat better every day. It analyzes key health data, dietary patterns, medical conditions, and nutrient needs to build highly personalized meal recommendations.

AI is not just digitizing recipes; it is transforming them into preventive healthcare tools.

1. Why India Needs an AI-Powered Healthy Cookbook

A. Lifestyle Diseases Increasing Rapidly

As per ICMR:

1 in 4 Indians has lifestyle disorders
Diabetes prevalence crossed 100 million
23% of adults have hypertension
Obesity rates rising annually

Diet is the first line of prevention.

B. Lack of Diet Awareness

Most Indian households:

Cook without portion planning
Consume excess sugar, salt, and oil
Lack awareness of micronutrients

AI simplifies nutrition into daily habits.

C. Busy Urban Lifestyle

People lack time to:

Plan meals
Track nutrition
Measure macros

AI automation removes friction.

D. Need for Personalized Nutrition

Every condition requires unique dietary rules:

Diabetes ? Low GI
Heart disease ? Low sodium
PCOS ? Anti-inflammatory meals
High cholesterol ? Fiber-rich foods

AI customizes meals at scale.

2. How the AI-Powered Healthy Cookbook Works

The AI engine uses:

Medical history
Lab results
Eating patterns
Food preferences
Allergies
Cultural diet habits
Activity level

It then creates:

Personalized recipes
Daily menus
Ingredient lists
Smart calorie distributions
Nutrition scoring

Each recipe is rated on:

Sugar load
Salt load
Trans-fat score
Vitamin & mineral density
Protein balance

3. Key Features of the AI-Powered Cookbook

1. Personalized Recipes for Every Individual

Every meal recommendation is built uniquely for the user.

2. AI Nutrition Score

Each recipe receives a score based on how healthy it is.

3. Disease-Specific Cookbooks

AI modifies:

Salt
Sugar
Oil
Carbs
Fiber

based on the medical condition.

4. Meal Plans Auto-Generated Every Day

Breakfast, lunch, dinner + snacks.

5. Ingredient Optimization

AI suggests:

Cost-effective ingredients
Healthy alternatives
Portion control tips

6. Integration with Wearables

If the user tracks steps, BP, glucose or calories, AI adjusts meals.

4. Benefits of the AI-Powered Healthy Cookbook

1. Supports Weight Loss Naturally

Balanced portions and calorie control.

2. Helps Manage Diabetes

Low GI recipes and sugar-controlled meal plans.

3. Improves Heart Health

Reduced sodium, low-cholesterol meals.

4. Boosts Immunity

High-antioxidant recipes and nutrient-dense meals.

5. Prevents Nutrient Deficiency

Balanced micronutrient planning.

6. Saves Time & Money

Optimized grocery lists and simple recipes.

5. How SecondMedic Uses AI Nutrition for Preventive Healthcare

SecondMedic integrates AI nutrition into:

Chronic disease programs
Preventive screening plans
Teleconsultations
Weight management
Diabetes reversal programs
Healthy eating education

Doctors and dietitians combine medical expertise with AI-generated insights for maximum results.

6. Example of an AI-Generated Daily Menu

Breakfast: Vegetable dalia + green tea
Lunch: Multi-grain roti + dal + spinach sabzi
Snack: Fox nut trail mix
Dinner: Grilled paneer bowl with quinoa
AI Score: 92/100

Balanced macros, low sugar, low sodium.

7. Future of AI-Driven Nutrition in India

The future will include:

Fully automated meal planning
AI-powered grocery shopping
Smart kitchen appliances connected to health profiles
Precision cooking for diseases
Real-time nutritional correction

India is entering the era of tech-enabled nutrition intelligence.

Conclusion

The AI-powered Healthy Cookbook is not just a recipe collection-it is a personalized preventive healthcare companion. It transforms how Indians eat, helping them manage chronic conditions, optimize nutrition, and build long-term healthy habits. With SecondMedic’s AI integration, healthy eating becomes simple, smart, and sustainable.

Explore personalized AI nutrition at:
www.secondmedic.com

References

ICMR Nutrition & Diet Study
National Family Health Survey (NFHS-5)
NITI Aayog Digital Health Report
Lancet Nutrition Research India
WHO Healthy Eating Guidelines

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