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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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Dairy-Free Options for All: A Comprehensive SecondMedic Guide for India

Dairy consumption has long been a part of Indian dietary culture, but rising awareness of digestive health, metabolic concerns, acne, inflammation and lactose intolerance has encouraged many individuals to explore dairy-free alternatives. India is experiencing a significant shift toward plant-based nutrition as people prioritise preventive health, gut comfort and personalised dietary choices.

SecondMedic’s nutrition experts emphasise evidence-based, dairy-free patterns that support digestion, hormonal balance, metabolic stability and overall wellbeing. This guide explores the best dairy-free options in India, their health benefits and how they integrate into daily preventive care.

Why Dairy-Free Eating Is Growing in India

1. Rising Lactose Intolerance

According to ICMR Digestive Health Trends, a high percentage of Indian adults experience lactose intolerance due to decreased lactase enzyme activity.

Common symptoms include:

Bloating
Gas
Acidity
Diarrhoea
Skin flare-ups

Dairy-free alternatives eliminate these discomforts.

2. Skin & Hormonal Concerns

Dairy may influence acne, PCOS symptoms and inflammation in certain individuals.

3. Improved Digestibility

Many plant-based options are easier on the gut and reduce inflammation.

4. Increasing Nutrition Awareness

NFHS-5 highlights micronutrient deficiencies-including Vitamin D and B12-leading people to choose fortified dairy-free alternatives.

Popular Dairy-Free Options in India

1. Almond Milk

Rich in Vitamin E and naturally low in calories.
Ideal for smoothies, coffee and cereal.

2. Soy Milk

High in protein and often fortified with calcium.
Great for cooking and baking.

3. Oat Milk

Creamy texture, high in soluble fibre.
Excellent for lattes and desserts.

4. Coconut Milk

Rich flavour, suitable for Indian curries and smoothies.

5. Nut-Based Yoghurt

Cashew and almond curds have become widely available.
Probiotic varieties support gut health.

6. Tofu & Plant-Based Paneer

Excellent protein source for vegetarians.

7. Lactose-Free Dairy

For those who prefer traditional taste without digestive discomfort.

Nutritional Benefits of Dairy-Free Options

1. Reduced Inflammation

Studies in Lancet Public Health show improved gut comfort among individuals switching to dairy-free diets.

2. Hormonal Balance

Plant-based alternatives help regulate insulin, estrogen and androgen patterns-especially valuable for PCOS and thyroid care.

3. Weight Management

Lower calorie load and better digestibility support metabolic health.

4. Allergy-Friendly Choice

A safe option for individuals sensitive to casein or whey proteins.

How to Build a Balanced Dairy-Free Diet

Ensure calcium intake:

Choose fortified plant milks.

Include plant proteins:

Tofu, dals, nuts and seeds.

Add healthy fats:

Ground flaxseed, chia and almonds.

Combine traditional and modern options:

Oat milk chai, tofu tikka, nut curd raita.

SecondMedic’s AI nutrition scoring helps evaluate vitamin density and carbohydrate load for optimal choices.

Dairy-Free Meal Examples

Breakfast

• Oats cooked with almond milk
• Fruit + chia seeds + nuts

Lunch

• Millet khichdi with tofu
• Vegetable salad with tahini dressing

Snack

• Coconut yoghurt with berries

Dinner

• Stir-fry vegetables with tofu
• Whole-grain roti + plant-based curd

Conclusion

Dairy-free options provide flexible, nutritious and preventive pathways for individuals across India. Whether motivated by digestive comfort, metabolic health, ethical choices or personal preference, dairy-free alternatives support long-term wellness. SecondMedic helps individuals evaluate and incorporate dairy-free nutrition through expert consultations, AI-based analysis and personalised dietary planning.

References

• ICMR Digestive Health & Lactose Intolerance Study
• National Family Health Survey (NFHS-5) - Nutrition & Dietary Patterns
• NITI Aayog - Plant-Based Nutrition & Preventive Wellness Framework
• WHO Guidelines on Healthy Dietary Alternatives
• Lancet Public Health - Dairy-Free Diets & Inflammation Research
• Statista India Plant-Based Food Market Analysis
• EY-FICCI Food Innovation & Health Trends Report

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