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Published on: May 31, 2021
1 minute read
By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail"

REGN-COV2 – Artificial "antibody cocktail"

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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Digital Pharmacy Platforms India: How SecondMedic Is Transforming Medicine Access Through Technology

India’s healthcare system is rapidly digitizing, and one of the most impactful innovations is the rise of digital pharmacy platforms. These platforms make it easier for people to order medicines online, manage prescriptions, and access healthcare services without visiting a physical store.

As chronic diseases, online consultations, and digital health records become more common, digital pharmacy solutions are now a vital part of India's healthcare infrastructure. SecondMedic plays a key role in this evolution by providing secure, fast, and integrated digital pharmacy services.

What Are Digital Pharmacy Platforms?

Digital pharmacy platforms are online systems that allow users to:

Order prescription medicines
Upload or sync digital prescriptions
Schedule refills
Purchase OTC products
Track orders
Access pharmacist support

Instead of visiting a traditional pharmacy, users can manage medication needs from anywhere in India.

Why Digital Pharmacies Matter in India

India sees high demand for medicines due to:

Rising chronic diseases
Aging population
Urban mobility challenges
Increasing telemedicine adoption
Growing digital health awareness

Digital pharmacies bridge the gap between medical consultation and medication access.

Key Benefits of Digital Pharmacy Platforms

1. Convenience and Accessibility

Patients can order medicines anytime, especially helpful for elderly individuals or those living in remote areas.

2. Time and Cost Savings

Digital ordering eliminates long queues, multiple store visits, and pricing uncertainties.

3. Verified, Authentic Medicines

Reputed platforms ensure drugs come from licensed pharmacies with full batch traceability.

4. E-Prescription Integration

Digital prescriptions reduce manual errors and support seamless ordering.

5. Chronic Disease Medication Management

Automated refill reminders and scheduled deliveries help maintain treatment consistency.

6. Privacy and Discretion

Useful for sensitive medication categories where users may prefer confidential ordering.

The Growing Digital Pharmacy Market in India

According to Statista 2025:

The Indian e-pharmacy market is expected to reach USD 10 billion by 2027.
Nearly 35 percent of urban households now use digital pharmacy services.
Chronic disease patients are the largest user segment.

Government initiatives like ABDM also promote secure and standardized digital prescriptions.

SecondMedic’s Digital Pharmacy Ecosystem

SecondMedic integrates pharmacy services seamlessly within its broader digital health platform.

1. Online Medicine Ordering

Users can order medicines directly through the SecondMedic app or website.

2. E-Prescription Sync

Prescriptions from SecondMedic doctors sync automatically, reducing errors and delays.

3. Verified Inventory

All medicines are sourced from certified pharmacies with temperature-controlled storage and valid expiry cycles.

4. Chronic Care Refill System

For diabetes, hypertension, thyroid disorders, and cardiac conditions, patients can schedule monthly refills.

5. Real-Time Tracking

Users get live updates on order status, dispatch, and delivery.

6. Secure Payment Gateway

Digital payments are supported through encrypted channels, ensuring safety and transparency.

7. Integration with Medical Consultations

After virtual consultations, prescribed medicines can be ordered instantly on the same platform.

How Digital Pharmacy Platforms Support Telemedicine

Telemedicine has become a cornerstone of modern healthcare. Digital pharmacies complement this by:

Enabling immediate access to prescribed medicines
Ensuring continuity of care
Reducing patient dependency on physical pharmacies
Streamlining doctor-to-pharmacy communication

Together, they create an efficient, patient-centered care loop.

Challenges in India’s Pharmacy System and How Digital Platforms Solve Them

1. Fragmented Pharmaceutical Distribution

Digital systems bring transparency and accountability.

2. Prescription Mismanagement

E-prescriptions minimize errors and duplication.

3. Limited Accessibility in Rural Areas

Digital ordering delivers medicines directly to underserved regions.

4. Inconsistent Medicine Availability

Real-time inventory ensures availability and alternatives.

5. Lack of Patient Awareness

Digital platforms offer information on dosage, interactions, and side effects.

Regulatory Framework for Digital Pharmacies in India

To ensure safety and compliance, digital pharmacies follow:

Drugs and Cosmetics Act (1940)
Pharmacy Practice Regulations
ABDM standards for digital prescriptions
DPDP Act for data security
CDSCO guidelines for online pharmacies

SecondMedic maintains full compliance with regulatory requirements.

Future of Digital Pharmacy in India

The sector is expected to grow due to:

AI-based medicine recommendations
Smart refill systems
Blockchain for supply chain verification
Automated pharmacy logistics
Drone-based delivery pilots in some states

SecondMedic is actively building tools to support next-generation pharmacy automation and integrated digital care.

Why Patients Trust SecondMedic’s Pharmacy System

Authentic and verified medicines
Transparent pricing and secure payments
Direct connection with healthcare consultations
Support for chronic care medication
Nationwide delivery capability
User-friendly ordering process
Compliance with all digital health safety standards

SecondMedic brings reliability, convenience, and safety under one unified digital healthcare platform.

Conclusion

Digital pharmacy platforms are redefining how India accesses medicines. They improve convenience, enhance safety, support telemedicine, and empower patients to manage chronic conditions more effectively. SecondMedic’s digital pharmacy provides an integrated solution that combines e-prescriptions, secure ordering, and nationwide delivery to simplify healthcare access.

To order medicines or explore digital pharmacy services, visit www.secondmedic.com

References

Statista – India E-Pharmacy Market Outlook 2025
IMARC Group – Digital Healthcare Market India 2025
NITI Aayog – Digital Health Tech Landscape 2024
ABDM – Digital Prescription Guidelines
FICCI – Healthcare Innovation Report 2024

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