• Published on: May 31, 2021
  • 1 minute read
  • By: Dr Rajan Choudhary

REGN-COV2 – Artificial "antibody Cocktail" 

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REGN-COV2 – Artificial "antibody cocktail" 

Recently a new drug was approved for use in COVID patients in India. Known as REGN-COV2, this new therapy is based on monoclonal antibodies targeting the SARS-CoV-2 virus responsible for COVID. So how does it work? And is there any evidence behind the treatment?

Monoclonal antibodies are made from components of the human immune system. When the human body recognizes a bacteria or virus in the body, the immune system recognizes and processes proteins on the surface of that bacteria or virus. This is presented to the adaptive immune system, and antibodies have produced that lock onto these surface proteins, neutralizing their function and also tagging them for destruction by other white blood cells.

If we identify antibodies capable of efficiently tagging and neutralizing a certain virus, we can identify the cell capable of producing that antibody, clone it and produce it in vast quantities. The antibodies produced from this cloned cell line will be able to target the virus at the same efficiency and have the same ability to neutralize the virus. Just like with vaccines, there is a risk of mutations developing, resulting in changes in the surface protein that reduce binding and neutralizing effects of the antibodies, allowing them to escape and continue to cause disease

REGN-COV2 uses two neutralizing antibodies (Casirivimab/imdevimab), in an effort to minimize the ability of a mutant virus to develop resistance against the antibody cocktail, as the virus would need to develop mutations canceling both antibodies out at once. These antibodies neutralize the receptor-binding domain of SARS-CoV-2 spike protein, preventing viral entry through ACE2 receptors.

In a study published in the New England Journal of Medicine (one of the most prestigious journals in the medical field) data from 275 patients showed a drastic reduction in viral load in patients treated with REGN-COV2. This is clinically significant as hospitalized patients with severe symptoms have higher viral counts than non-hospitalized or asymptomatic patients, suggesting the hypoxaemic, shortness of breath symptoms are related to the viral count and resulting exaggerated immune response.

Based off this result the European Medicines Agency approved the use of REGN-COV2 antibody cocktail in patients who do not require supplemental oxygen but are at high risk of progressing to severe COVID-19.

FDA regulations currently recommend it for patients who are COVID positive with risk factors that may result in their hospitalization but do not recommend it for patients who are already hospitalized, requiring O2 therapy because of COVID or need chronic O2 therapy.

Those that fall into the high-risk categories include patients with a high BMI (over 35), diabetes, on immunosuppressive treatment or with an immunosuppressive disease, over 65 years of age or those with chronic diseases such as renal disease, cardiovascular disease, COPD, or other developmental disorders.

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Employee Wall

Employee Wall of Fame: Celebrating Uniqueness to Build a Positive Workplace Culture

In today’s evolving workplaces, employee engagement is no longer driven solely by compensation or job titles. People seek recognition, inclusion and a sense of belonging. One of the most effective yet simple ways to achieve this is through an Employee Wall of Fame. By celebrating individuality and contribution, organisations can create a culture where employees feel seen, valued and motivated.

Recognition is not a luxury. It is a fundamental driver of organisational wellbeing and performance.

 

Why Recognition Matters in the Workplace

Recognition fulfills a basic human need: appreciation.

When employees feel recognised:

  • morale improves

  • motivation increases

  • loyalty strengthens

  • burnout reduces

According to global workplace studies, lack of recognition is one of the top reasons for employee disengagement.

 

What Is an Employee Wall of Fame?

An Employee Wall of Fame is a physical or digital space dedicated to highlighting employees for their achievements, values, creativity or unique strengths.

It may showcase:

  • professional accomplishments

  • teamwork contributions

  • innovation and problem-solving

  • leadership qualities

  • personal milestones

The focus is not competition, but appreciation.

 

Celebrating Uniqueness, Not Just Performance

Traditional recognition often focuses only on targets or numbers.

A Wall of Fame expands recognition to include:

  • collaboration

  • consistency

  • empathy

  • creativity

  • positive attitude

This approach ensures diverse strengths are valued.

 

Psychological Impact of Workplace Recognition

Recognition positively affects mental health.

Benefits include:

  • improved self-esteem

  • reduced stress

  • increased sense of purpose

  • stronger emotional connection to work

WHO recognises psychosocial wellbeing as a key component of healthy workplaces.

 

Inclusion and Belonging Through Recognition

Celebrating uniqueness supports inclusion.

It helps:

  • recognise diverse backgrounds

  • reduce bias

  • promote equal visibility

When employees see people like themselves being appreciated, trust and belonging grow.

 

Employee Wall of Fame as a Culture-Building Tool

Culture is shaped by what organisations choose to celebrate.

A visible Wall of Fame:

  • reinforces company values

  • sets behavioural standards

  • inspires others

It becomes a living reflection of organisational culture.

 

Types of Recognition on a Wall of Fame

Achievement-Based Recognition

For milestones, project success or innovation.

Value-Based Recognition

For demonstrating company values such as integrity or teamwork.

Peer Recognition

Employees nominate colleagues, increasing engagement.

Personal Growth Recognition

Celebrating learning, upskilling or personal achievements.

 

How an Employee Wall of Fame Improves Engagement

Engaged employees:

  • perform better

  • collaborate more

  • stay longer

EY-FICCI workplace studies show recognition-driven programs significantly improve engagement scores.

 

Impact on Productivity and Performance

Recognition creates positive reinforcement.

Employees who feel valued:

  • take ownership of work

  • show initiative

  • maintain consistency

Appreciation fuels sustained performance.

 

Supporting Mental Wellbeing at Work

Recognition reduces workplace stress by:

  • validating effort

  • reducing feelings of invisibility

  • encouraging positive feedback loops

Mental wellbeing improves when employees feel respected and acknowledged.

 

How to Design an Effective Employee Wall of Fame

Key principles include:

  • inclusivity

  • transparency

  • fairness

  • consistency

Clear criteria prevent bias and ensure credibility.

 

Physical vs Digital Wall of Fame

Physical Wall

Creates visual impact in office spaces.

Digital Wall

Ideal for remote or hybrid teams.

Both formats can coexist for maximum reach.

 

Frequency of Updates Matters

Stale recognition loses impact.

Best practices include:

  • monthly highlights

  • quarterly rotations

  • special occasion features

Fresh content sustains enthusiasm.

 

Role of Leadership in Recognition

Leadership participation strengthens impact.

When leaders:

  • nominate employees

  • share appreciation publicly

recognition becomes part of organisational identity.

 

Employee Participation and Ownership

Encouraging peer nominations:

  • increases engagement

  • reduces hierarchy

  • builds mutual respect

Recognition becomes a shared responsibility.

 

Measuring the Impact of Recognition Initiatives

Impact can be assessed through:

  • engagement surveys

  • retention metrics

  • feedback forms

  • participation rates

Data-driven insights help refine programs.

 

Long-Term Benefits of Celebrating Uniqueness

Over time, organisations experience:

  • stronger culture

  • higher retention

  • improved employer branding

  • healthier workplace relationships

Recognition is a long-term investment, not a one-time activity.

 

Common Mistakes to Avoid

Avoid:

  • recognising only top performers

  • favouritism

  • lack of transparency

  • irregular updates

Consistency and fairness are essential.

 

Employee Wall of Fame as Part of Holistic Wellness

Recognition complements:

  • mental health initiatives

  • team-building programs

  • wellness activities

A supportive culture enhances overall wellbeing.

 

Conclusion

An Employee Wall of Fame is more than a display—it is a statement of values. By celebrating uniqueness and recognising diverse contributions, organisations create workplaces where people feel valued, motivated and connected. In an era where employee wellbeing and engagement define success, recognition-driven initiatives like a Wall of Fame play a vital role in building resilient, inclusive and high-performing teams. Celebrating people is not just good culture—it is good leadership.

 

References

  • World Health Organization (WHO) – Workplace Mental Health and Wellbeing
  • EY-FICCI – Employee Engagement and Workplace Culture Reports
  • NITI Aayog – Future of Work and Organisational Wellbeing Studies
  • Lancet – Psychosocial Work Environment Research
  • Statista – Global Employee Engagement and Recognition Trends

See all

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