• Published on: Apr 28, 2020
  • 4 minute read
  • By: Dr Rajan Choudhary

Strokes In The Young And How COVID Causing Clotting Disorders?

  • WhatsApp share link icon
  • copy & share link icon
  • twitter share link icon
  • facebook share link icon

Strokes in the young and healthy: how is COVID causing clotting disorders?

In the news, there has been a rush in stories linking Strokes in young and healthy patients, patients who also have COIVD-19. This is certainly worrying news, and at first glance, it is difficult to explain. How does a respiratory virus, one that is very similar to the coronavirus responsible for the common cold, cause such serious issues in a completely unrelated organ system? In this two-part series we will first go over the basics of clotting and its function, how clotting can cause problems, and finally how COVID can lead to clotting disorders.

STROKES

Before we progress, if you or a family member are having any of the following symptoms, contact your local emergency services immediately. Strokes can be devastating, and treatment needs to be given as soon as possible to save as much of the brain as we can. Early recognition can be the difference between manageable long term effects and crippling disability.

Remember, act F.A.S.T

  • Facial Droop on one side
  • Arm or hand on one side feels numb or weak with reduced power (same in one leg)
  • Slurred speech making it difficult to understand
  • Time to phone an ambulance

Other symptoms can include sudden loss in balance, sudden loss in vision in one eye, problems swallowing, and more.

PLUGGING A HOLE

We have an intricate network of vessels to transport oxygen, nutrients, and signals to cells and organs across our bodies. Damage to these blood vessels causes blood loss, reduction in oxygen and nutrient delivery to these cells, and organ damage if the issue isn’t rectified. Failure in multiple organ systems across the body will eventually lead to death. Our blood has cells and proteins that work together to form a clot at the site of injury. This acts as a plug to physically stop the leak, but also encourages repair of the blood vessel and surrounding tissue.

A clot can be triggered in three different ways: blood stasis (pooling up in one area), exposure of blood vessel lining, and pro-coagulant factors released into the blood. When triggered a coagulation cascade occurs to form the building blocks of a clot – it works so well that even a small trigger can create a response big enough to repair the damage. These form a mesh trapping platelets and other blood cells into a plug. Immune cells also arrive to destroy any organisms that might enter from the trauma site that caused the injury, and these immune cells also instruct nearby cells to begin the repair process.

As with everything in our body the whole process is very tightly regulated. The cascade has triggers and accelerators, but it also has brakes. These brakes stop a clot from growing too big, or from clots forming spontaneously when they are not needed. They also help dissolve a clot once the vessel is repaired and it isn’t needed.

WHEN IT GOES WRONG

Heart attacks and strokes. These devastating cardiovascular diseases are well recognized by the public as a leading cause of disability and death. Both can be caused by abnormal clotting. How does our finely tuned clotting cascade turn abnormal? Let's go back to the three triggers of blood clotting.

Vessel damage: Eating a high fat and cholesterol diet can cause fatty plaques to build up in our arteries. This is known as atherosclerosis, and it is extremely common. The plaques can narrow your arteries and reduce blood flow. If this happens in your coronary arteries supplying your heart muscles, your heart might not receive enough oxygen when you exercise or exert yourself. This can cause chest pain, known as angina.

If the plaques burst open it can expose the vessel lining, causing a large clot to form. This clot can become dislodged and be carried away by the blood. It will eventually get lodged in a narrow artery, blocking it and stopping blood from entering. The tissue and cells supplied by that artery will not receive oxygen and eventually die. If this happens in the coronary arteries it can cause a heart attack. In the arteries supplying the brain, it can cause a stroke, leading to neurological deficits.

THIS IS THE MOST IMPORTANT LEARNING POINT, and this is why a healthy diet low in fat and sugars is so important. 

Stasis: Our heart pumps blood at high pressures through the arteries. But in the veins, there is very little pressure to drive the blood back to the heart. In our arms and head, gravity helps blood flow down to the heart. But from our legs? When we walk the muscles in our legs squeeze the veins and move the blood. Valves make sure this flow is only one way, back to the heart.

If we sit or lie down in one place and don’t move, the blood isn’t pumped back and pools up in our legs, causing a clot to form. This usually happens in our calves (known as a DEEP VEIN THROMBOSIS, or DVT). The calf becomes swollen, painful, red, and hot. If this clot is dislodged, it can end up in our lungs causing a PULMONARY EMBOLISM. A large PE can block blood from entering the lungs and can be fatal. This is why you should take regular walks on long haul flights, to prevent blood from pooling.

Pro-coagulant: Sometimes the factors in our blood responsible for triggering a clot can be triggered accidentally. Cigarette smoke contains many toxins and harmful chemicals that, when inhaled, end up in your blood. These chemicals can cause damage to vessel linings, and also cause the clotting cascade to be triggered more easily. Some medications, such as the Combined Oral Contraceptive Pill, also have a similar effect, though the risk of getting a clot is still very low.

The immune system can also trigger a clot. The protein mesh formed in the blood can also capture bacteria and viruses around an infection site, making it easier for immune cells to find and destroy these invading organisms. In cancer patients, this process is sometimes triggered by unregulated cancer cells.

WHAT HAVE WE LEARNT?

Our clotting system stops us from bleeding to death from a small wound. People who have bleeding disorders are clear examples and need to be extremely careful if they injure themselves. But unregulated, our body can end up harming itself. If there is one thing you should take away from this, it is that a high sugar/high-fat diet with little exercise can directly increase your risk of having a heart attack or stroke. This is why doctors emphasize so much the importance of a good diet and exercise.

In our next blog, we will look at how this clotting problem is implicated in COVID patients.

Dr Rajan Choudhary, UK, Chief Product Officer, Second Medic Inc

www.secondmedic.com

Read Blog
How Your Sleep Schedule Affects Digestion

How Your Sleep Schedule Affects Digestion

In today’s fast-paced world, staying up late has become a norm—whether for work, binge-watching, or scrolling on phones. But did you know your late-night habits can negatively impact your digestion?

Yes! Your sleep schedule and digestive health are deeply connected. Let’s explore how poor sleep affects your gut, the symptoms to watch for, and simple ways to improve both.

 

Sleep and Gut – What’s the Link?

Your body follows a 24-hour internal clock, called the circadian rhythm. This biological clock not only controls your sleep-wake cycle but also governs other body functions—including digestion.

When you sleep on time, your digestive system gets enough rest and follows its natural detox and repair routine. But irregular or insufficient sleep disrupts hormonal flow, slows down digestion, and affects gut bacteria.

 

Signs Your Sleep Is Hurting Your Digestion

Let’s look at how poor sleep shows up in your gut health:

 

1. Bloating & Gas in the Morning

Waking up with a heavy, bloated stomach could mean your food didn’t digest properly overnight due to late meals and sleep disruption.

 

2. Constipation or Irregular Bowel Movements

Your colon is most active in the early morning. Late nights confuse this rhythm, making bowel movements irregular or difficult.

 

3. Frequent Acidity or Heartburn

Poor sleep posture or sleeping soon after eating can lead to acid reflux and heartburn at night or in the morning.

 

4. Low Appetite or Indigestion

Sleep deprivation weakens stomach acid production and gut motility, leading to poor breakdown of food.

 

5. Brain Fog and Fatigue

Your gut produces over 90% of serotonin—a chemical that affects mood and alertness. Poor sleep affects gut function, which in turn impacts mental clarity.

 

Your Gut Microbiome Has a Sleep Cycle Too

Inside your intestines live trillions of bacteria—your gut microbiome. These bacteria help digest food, absorb nutrients, and maintain immunity.

Recent studies show that gut bacteria also follow a circadian rhythm. When your sleep is disturbed, these good bacteria get confused too—leading to:

  • Poor digestion
     

  • Inflammation
     

  • Weakened immunity
     

  • Increased sugar cravings
     

 

What’s the Ideal Sleep Schedule for Good Digestion?

Aim for:

  • Sleeping between 10 PM and 6 AM
     

  • 7–8 hours of quality, uninterrupted rest
     

  • Avoiding meals 2–3 hours before bedtime
     

This helps your digestive organs function properly during sleep and your body to detox naturally.

 

6 Simple Tips to Improve Sleep and Digestion Together

 

1. Follow a Fixed Sleep Schedule

Go to bed and wake up at the same time daily—even on weekends.

 

2. Avoid Heavy Late-Night Meals

Have dinner 2–3 hours before bed. Choose light, easy-to-digest foods.

 

3. Limit Caffeine and Sugar in Evenings

They disturb sleep patterns and irritate your digestive lining.

 

4. Add a Night Walk

A 10–15 minute slow walk after dinner improves digestion and helps your body wind down.

 

5. Practice Screen-Free Time Before Bed

Blue light from screens affects melatonin production—try reading, journaling, or deep breathing instead.

 

6. Stay Hydrated During the Day

But avoid too much water just before bed to prevent waking up to pee.

 

When to See a Doctor

If you face chronic indigestion, acidity, constipation, or fatigue, even with a good lifestyle, consult a healthcare provider. You may need tests for:

  • Gut health
     

  • Liver enzymes
     

  • Hormone levels
     

  • Vitamin deficiencies
     

  • Sleep disorders like sleep apnea
     

You can easily book these via SecondMedic.com, which offers Thyrocare lab services and home sample collection.

 

Conclusion

Your gut and brain are best friends. And your sleep schedule plays a major role in keeping this bond healthy.

If you’ve been feeling bloated, tired, or irregular lately—it may not be your food, but your sleep. Now that you know how your sleep schedule affects digestion, try making small changes to improve both. Better sleep = better gut = better life.

See all

Live Doctor consultation
Live Doctor Chat

Download Our App & Get Consultation from anywhere.

App Download
call icon for mobile number calling and whatsapp at secondmedic