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Published on: Apr 04, 2020
2 minute read
By: Dr Rajan Choudhary

THE CHALLENGES FACED IN MAKING A VACCINE FOR COVID-19 — Part 2

Previously we’ve seen the difficulties researches face in trying to make a vaccine. But even if we make a vaccine, that’s just half the battle. Viruses are unique because they can mutate, and they can mutate to astonishing degrees. In humans mutations to tiny parts of our DNA can cause severe diseases or even death. In viruses mutations can change their structure, making them more infective and giving them a new coat. It gives them a survival advantage, the ability to evade our immune system and make our vaccines ineffective. This is why we need a new flu vaccine every year.

If it takes months to a year to develop a vaccine, it will be based off the virus found in December 2019. By this time the virus may have spread and mutated to such a degree that it is not effective. This does not mean all the effort was for nothing. Going through the steps and understanding the issues faced with making a COVID-19 vaccine can make the process quicker for subsequent vaccines against its mutated versions.

https://www.sciencealert.com/who-says-a-coronavirus-vaccine-is-18-months-away So Long to Develop a Vaccine

FAILURES FROM THE PAST

These issues were faced during the Ebola and Zika virus epidemics, and many large companies are understandably hesitant to develop vaccines for COVID-19. Ebola first broke out in 2014, and it was only in December 2019 that the first vaccine was approved for use by the European Commission and the United States. This is despite multiple large institutes in Canada and the UK working together to develop it.

13 different Ebola vaccine candidates had been identified soon after the outbreak, but none had been tested on humans. Unfortunately this is the most expensive part of development, and the area biopharmecuticals stand to loose the most money. Return on investments is also low, since epidemics usually take place in poorer countries, and the potential customers are unable to pay the high prices for these brand new treatments. It is an unfortunate realisation that research into medicines is driven by rich countries, for diseases that affect the rich.

https://newint.org/features/web-exclusive/2016/06/16/why-did-the-market-fail-to-produce-an-ebola-vaccine Ebola

WHERE ARE WE NOW?

This is all well and good, but what does it mean for COVID-19? We know we cannot rush a vaccine, because a poorly designed vaccine with unknown side effects can cause more harm than good, especially if given to children or the elderly. Currently the WHO are tracking 31 different attempts at making a COVID-19 vaccine, using different methods as discussed before. All of these are currently in the pre-clinical stage, focusing on isolating parts of the virus and creating a target the body will recognise and react to.

Researchers at the University of Queensland were one of the first to start using the genetic code of COVID-19, released openly by Chinese researchers. They have developed a test vaccine within 6 weeks using state-of-the-art genetic techniques, used for the first time. If animal models prove successful then human testing might begin within 6 months. In the pharmaceutical industry advancements this quick are almost unheard of.

Additionally over 293 clinical trials are taking place in China using existing drugs on the market. The advantage is we already know these drugs are safe to use in humans, but we are trying to work out if they will work against COVID-19. Some scientists are also looking at medications that were initially developed against SARS and MERS, but never completed because these outbreaks died down and the medication was no longer required.

https://www.aljazeera.com/news/2020/03/china-recovered-develop-effective-covid-19-treatments-200302082850237.html COVID-19 treatments

https://www.who.int/blueprint/priority-diseases/key-action/novel-coronavirus-landscape-ncov.pdf?ua=1 WHO news

https://www.theverge.com/2020/2/28/21156385/covid-coronavirus-vaccine-treatment-moderna-remdesivir-research COVID-19 treatment

Its not all doom and gloom. Challenges drive innovation, and we are already benefitting from this. New forms of genetic sequencing, new methods for extracting viral proteins, new techniques in creating a vaccine. These innovations are already benefitting us on the drive to create an effective vaccine for COVID-19, and they will benefit us in the future when the next pandemic hits.

Dr Rajan Choudhary, Product Manager Second Medic UK

www.secondmedic.com

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Switch Soda with Detox Water: A Simple Step Toward Better Metabolic Health

Soda and sugary beverages have become a major contributor to India’s rising burden of metabolic diseases. According to NFHS-5 and ICMR data, high intake of sugary drinks significantly increases the risk of obesity, high blood sugar, fatty liver disease and heart problems. Replacing these drinks with detox water is one of the easiest and most sustainable lifestyle changes for preventive health.

Detox water is not a medical treatment-it is a healthy hydration alternative that supports the body’s natural processes. SecondMedic encourages simple, evidence-based swaps like this to help individuals improve daily habits without drastic diets.

Why Soda Is a Major Health Concern in India

1. Extremely high sugar content

A single can of soda contains:

8-10 teaspoons of sugar
Over 140 empty calories

This spikes glucose levels and increases insulin resistance.

2. Artificial additives

Flavours, colours and preservatives strain the liver and may worsen inflammation.

3. Link to chronic diseases

ICMR and Lancet studies show soda consumption increases risk of:

Type 2 diabetes
Hypertension
Weight gain
Non-alcoholic fatty liver disease (NAFLD)

4. Poor hydration

Soda does not hydrate the body. Caffeine and sugar can actually increase dehydration.

Benefits of Switching to Detox Water

Detox water provides hydration and additional wellness support through natural ingredients.

• Improved metabolism

Ingredients like lemon, ginger and cinnamon support metabolic balance.

• Better digestion

Mint and ginger soothe the digestive system.

• Stable blood sugar

Sugar-free detox blends prevent rapid glucose spikes.

• Enhanced hydration

Water absorption improves when infused with electrolytes and antioxidants.

• Reduced cravings

Replacing soda breaks dependence on sugar.

• Skin health improvement

Hydration + antioxidants help reduce dullness and inflammation.

Popular Detox Water Ingredients and Their Benefits

Lemon

Rich in vitamin C and antioxidants, helps improve digestion and immunity.

Mint

Reduces bloating and supports gut comfort.

Cucumber

Hydrates deeply and reduces water retention.

Cinnamon

Known for supporting stable blood sugar.

Ginger

Anti-inflammatory and excellent for digestion.

Apple slices

Add natural sweetness without added sugar.

Berries

High in antioxidants; good for heart health.

Easy Detox Water Recipes

1. Lemon + Ginger Detox

Supports metabolic health and digestion.

2. Cucumber + Mint Hydration Blend

Great for daily hydration and cooling.

3. Apple + Cinnamon Water

Helps stabilise glucose naturally.

4. Mixed Berry Infused Water

Boosts antioxidant levels for skin and heart health.

5. Turmeric + Lemon Detox

Mild anti-inflammatory properties.

How Detox Water Helps Reduce Soda Dependence

1. Replaces sweetness gradually

Natural fruit flavours reduce the urge for sugary beverages.

2. Keeps you full

Hydration decreases cravings, especially in the evening.

3. Offers variety

Different combinations keep the habit interesting.

4. Improves energy

Consistent hydration reduces fatigue and brain fog.

The Science Behind Hydration and Metabolic Health

According to WHO and NITI Aayog health reports:

Hydration improves nutrient transport
Helps maintain blood pressure
Aids liver detoxification
Supports kidney function

Soda disrupts these processes, while detox water supports them.

How SecondMedic Helps You Transition from Soda to Healthy Hydration

• AI Health Guide

Identifies sugar consumption patterns and suggests healthier beverage alternatives.

• Dietitian support

Provides personalised hydration plans for metabolic health.

• Preventive care tracking

Monitors progress for weight, energy and blood sugar.

• Health education

SecondMedic guides families, teenagers and adults on sustainable lifestyle swaps.

Tips to Make the Switch Successfully

1. Start gradually

Replace one soda per day with detox water.

2. Add natural flavour

Use citrus or herbs to enhance taste.

3. Keep it accessible

Carry a bottle to avoid impulse soda purchases.

4. Choose chilled detox water

Cold drinks create a similar refreshing experience.

5. Track your progress

Energy and digestion improve noticeably within 2-3 weeks.

Conclusion

Switching soda with detox water is a small step with big preventive health benefits. It reduces sugar intake, supports metabolic wellness, improves hydration and strengthens long-term health. With personalized recommendations from SecondMedic, this transition becomes easy, enjoyable and effective.

References

• ICMR - Sugar Consumption & Metabolic Health Report
• NFHS-5 - Obesity, Diet and Lifestyle Indicators
• NITI Aayog - Preventive Health & Hydration Behaviour Study
• WHO - Health Effects of Sugary Drinks
• Lancet - Soda Consumption & Disease Burden India
• Statista - Beverage Consumption Trends in India
• EY-FICCI - Lifestyle Behaviour & Preventive Health Report

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