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Published on: Nov 13, 2020
1 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Using The Cellular Handshake Against The Virus

Using the cellular handshake against the virus

In early November an interesting study was published in The Lancet Respiratory Medicine, describing the treatment of a severe COVID-19 patient with human recombinant soluble angiotensin-converting enzyme-2. By using the treatment, it was possible to see the disappearance of the virus swiftly from the patient's serum, nose, and lungs, as well as a reduction in the patients’ inflammatory markers. How was this achieved? And why is this so intriguing.

When we look at treating viruses, there are several strategies at work. You can prevent its spread by the use of social distancing or masks, you can use medications that prevent its replication (such as Tamiflu). Or you can stop the virus from entering the cells, the first step in viral replication.

SARS-CoV-2 appears to enter human cells through the ACE2 receptor. ACE2 is a protein in the cell membrane found across the human body, especially the lungs, heart, kidney and small intestine. It function is related to the Renin-Angiotensin System, a mechanism by which the kidneys control your blood pressure.

Angiotensin-Converting Enzyme converts angiotensin 1 to angiotensin 2, a hormone that causes blood vessels to constrict. ACE 2 instead converts it to a protein that causes dilation of blood vessels. This likely protects these critical organs and ensure they receive sufficient blood to perform their tasks. ACE2 is being investigated as a possible target for blood pressure medications.

The study used a genetically modified soluble form of ACE2 that mimics the protein found on human cell membranes. By increasing its availability in the blood, the SARS-CoV-2 virus binds to this protein, resulting in its inactivation, rather than entering lung cells and causing lung injury. Lab studies have shown that it can reduce viral growth by as much as 1000 to 5000 times, and phase 1 studies show it to be safe to use in people.

The actual described case was in a 45-year-old woman, hospitalized with COVID, suffering from severe shortness of breath, cough and fatigue. She was first treated with hydroxychloroquine and anticoagulants, but this proved ineffective, and the virus was causing increasing damage to her lungs. Nine days after her symptoms started, she received the ACE2 treatment for a week, with no side effects. This resulted in an increase in ACE2 activity (seen from her blood results), but also a marked decrease in multiple inflammatory markers associated with COVID-19, as well as a sharp decrease in COVID 19 numbers. Indeed, the viral load dropped from 32,000 per mL to just 270 per mL two days after treatment started. She was also able to produce antibodies against the virus, so this did not impair her from getting immunity.

It is certainly a very interesting case, though questions remain on how feasible it would be (as well as how expensive) to manufacture large quantities of this protein receptor for treatment use, as well as how it fairs in clinical trials.

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KEYWORD: Employee Wall of Fame – Celebrate uniqueness

In today’s competitive and fast-paced work environment, employee recognition plays a vital role in building a positive and productive workplace culture. While salary and benefits are important, appreciation and acknowledgment often have a deeper and longer-lasting impact on motivation.

An Employee Wall of Fame is a powerful yet simple initiative that celebrates individual contributions, highlights achievements and reinforces a culture of appreciation.

What Is an Employee Wall of Fame?

An Employee Wall of Fame is a recognition platform — physical or digital — that showcases employees who have demonstrated exceptional performance, creativity, teamwork or leadership.

It may include:

Employee photographs
Achievement descriptions
Monthly or quarterly awards
Customer appreciation highlights
Team milestones

This visible recognition fosters pride and belonging.

Why Celebrating Uniqueness Matters

Every employee brings distinct skills, experiences and perspectives to the organization. Recognizing uniqueness:

Encourages diversity
Builds confidence
Promotes innovation
Strengthens team cohesion

Appreciation creates an inclusive culture where everyone feels valued.

Benefits of an Employee Wall of Fame

1. Boosts Employee Morale

Public recognition reinforces positive behavior and motivates others to perform better.

Employees feel acknowledged for their hard work.

2. Enhances Productivity

When employees know their efforts are recognized, they are more likely to:

Stay engaged
Take initiative
Maintain consistent performance

Motivation translates into measurable productivity gains.

3. Strengthens Workplace Culture

Recognition fosters:

Respect
Team spirit
Healthy competition

A positive environment encourages long-term retention.

4. Encourages Continuous Improvement

Highlighting achievements sets performance benchmarks.

Employees strive to improve skills and meet high standards.

5. Improves Employee Retention

Feeling valued reduces turnover.

Recognition strengthens emotional connection with the organization.

Types of Employee Wall of Fame Models

Physical Recognition Board

Placed in office reception or common area.

Ideal for on-site teams.

Digital Wall of Fame

Hosted on company intranet or website.

Suitable for remote or hybrid teams.

Themed Recognition

Examples include:

Innovator of the Month
Team Player Award
Customer Champion
Wellness Ambassador

This allows diverse achievements to be celebrated.

How to Implement an Effective Wall of Fame

Define Clear Criteria

Establish transparent guidelines for selection.

Encourage Peer Nominations

Allow employees to nominate colleagues.

This increases participation and fairness.

Rotate Recognition Regularly

Monthly or quarterly updates maintain enthusiasm.

Share Stories

Include short narratives describing contributions.

Stories inspire others and personalize achievements.

Combine with Rewards

Certificates, small gifts or appreciation emails enhance impact.

Employee Recognition in the Indian Workplace

With evolving workplace dynamics in India, organizations are focusing more on employee engagement and cultural development.

Recognition programs like Employee Wall of Fame help companies build stronger employer branding and create motivating environments.

Such initiatives are particularly effective in fast-growing sectors such as healthcare, IT and startups.

Addressing Common Challenges

Avoid Bias

Use structured evaluation criteria.

Maintain Consistency

Ensure regular updates to sustain credibility.

Encourage Inclusivity

Recognize diverse roles, not just top performers.

Long-Term Impact on Organizations

Organizations that celebrate employee uniqueness often experience:

Higher engagement levels
Better teamwork
Increased innovation
Stronger organizational loyalty

Recognition transforms workplace dynamics positively.

Integrating Wall of Fame with Wellness Culture

Companies can align recognition with health and wellbeing initiatives, such as:

Fitness achievements
Community volunteering
Mental health advocacy

Celebrating holistic contributions promotes balanced development.

Conclusion

An Employee Wall of Fame is more than a decorative display — it is a strategic recognition tool that celebrates uniqueness and strengthens workplace culture.

By acknowledging achievements openly and consistently, organizations foster motivation, engagement and loyalty.

In an era where talent retention and employee satisfaction are critical, simple appreciation initiatives can create lasting impact.

Celebrating individuality is not just good for morale — it is essential for building resilient and high-performing teams.

Recognition inspires excellence, and excellence drives success.

References

World Health Organization – Healthy Workplace Framework
Harvard Business Review – Employee Recognition Research
Indian Journal of Occupational Health – Workplace Engagement Studies
Society for Human Resource Management (SHRM) – Recognition Reports
NITI Aayog – Workplace Wellness Strategies

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