• Published on: Nov 13, 2020
  • 1 minute read
  • By: Dr Rajan ( Medical Second Opinion Cell)

Using The Cellular Handshake Against The Virus

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Using the cellular handshake against the virus

In early November an interesting study was published in The Lancet Respiratory Medicine, describing the treatment of a severe COVID-19 patient with human recombinant soluble angiotensin-converting enzyme-2. By using the treatment, it was possible to see the disappearance of the virus swiftly from the patient's serum, nose, and lungs, as well as a reduction in the patients’ inflammatory markers. How was this achieved? And why is this so intriguing.

When we look at treating viruses, there are several strategies at work. You can prevent its spread by the use of social distancing or masks, you can use medications that prevent its replication (such as Tamiflu). Or you can stop the virus from entering the cells, the first step in viral replication.

SARS-CoV-2 appears to enter human cells through the ACE2 receptor. ACE2 is a protein in the cell membrane found across the human body, especially the lungs, heart, kidney and small intestine. It function is related to the Renin-Angiotensin System, a mechanism by which the kidneys control your blood pressure.

Angiotensin-Converting Enzyme converts angiotensin 1 to angiotensin 2, a hormone that causes blood vessels to constrict. ACE 2 instead converts it to a protein that causes dilation of blood vessels. This likely protects these critical organs and ensure they receive sufficient blood to perform their tasks. ACE2 is being investigated as a possible target for blood pressure medications.

The study used a genetically modified soluble form of ACE2 that mimics the protein found on human cell membranes. By increasing its availability in the blood, the SARS-CoV-2 virus binds to this protein, resulting in its inactivation, rather than entering lung cells and causing lung injury. Lab studies have shown that it can reduce viral growth by as much as 1000 to 5000 times, and phase 1 studies show it to be safe to use in people.

The actual described case was in a 45-year-old woman, hospitalized with COVID, suffering from severe shortness of breath, cough and fatigue. She was first treated with hydroxychloroquine and anticoagulants, but this proved ineffective, and the virus was causing increasing damage to her lungs. Nine days after her symptoms started, she received the ACE2 treatment for a week, with no side effects. This resulted in an increase in ACE2 activity (seen from her blood results), but also a marked decrease in multiple inflammatory markers associated with COVID-19, as well as a sharp decrease in COVID 19 numbers. Indeed, the viral load dropped from 32,000 per mL to just 270 per mL two days after treatment started. She was also able to produce antibodies against the virus, so this did not impair her from getting immunity.

It is certainly a very interesting case, though questions remain on how feasible it would be (as well as how expensive) to manufacture large quantities of this protein receptor for treatment use, as well as how it fairs in clinical trials.

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Kindness Week encourages

Kindness Week – Recognize Employees Going the Extra Mile

In today’s fast-paced corporate world, deadlines, targets and performance metrics often dominate workplace conversations. However, one powerful factor that consistently drives employee satisfaction and productivity is kindness.

Kindness Week is a meaningful initiative designed to celebrate employees who go beyond their defined roles, support their colleagues and contribute positively to workplace culture. Recognizing those who consistently go the extra mile not only boosts morale but also strengthens organizational values.

 

Why Kindness Matters in the Workplace

Kindness in professional settings includes:

  • Offering help without being asked
     

  • Supporting team members during stressful periods
     

  • Maintaining respectful communication
     

  • Appreciating others’ contributions
     

  • Showing empathy during challenges
     

These small actions significantly influence employee wellbeing and workplace harmony.

Research in organizational psychology indicates that workplaces with higher levels of appreciation and positive reinforcement experience:

  • Better employee engagement
     

  • Lower stress levels
     

  • Higher productivity
     

  • Improved retention rates
     

 

The Purpose of Kindness Week

Kindness Week serves multiple objectives:

1. Encourage Positive Behavior

By highlighting positive actions, organizations reinforce desirable behaviors.

2. Promote Appreciation

Employees feel valued when their efforts are acknowledged publicly.

3. Strengthen Team Bonds

Recognition fosters collaboration and trust.

4. Improve Workplace Morale

Celebrating contributions creates a supportive environment.

 

Benefits of Recognizing Employees Who Go the Extra Mile

Boosted Motivation

When employees know their efforts are noticed, they are more motivated to maintain high performance.

Increased Engagement

Recognition creates emotional connection with the organization.

Better Mental Wellbeing

Feeling appreciated reduces stress and burnout.

Enhanced Organizational Reputation

A positive work culture attracts talent and strengthens employer branding.

 

How to Celebrate Kindness Week

1. Employee Appreciation Awards

Create categories such as:

  • Kindness Champion
     

  • Team Support Star
     

  • Helping Hand Award
     

  • Positive Attitude Leader
     

Keep criteria transparent and inclusive.

 

2. Gratitude Wall

Encourage employees to post thank-you notes recognizing colleagues’ contributions.

This creates visible appreciation within the organization.

 

3. Leadership Acknowledgment

Managers and senior leaders can personally recognize employees during team meetings.

Direct appreciation from leadership increases impact.

 

4. Team Lunch or Wellness Event

Organize:

  • Welcome lunches
     

  • Healthy snack days
     

  • Mindfulness sessions
     

  • Team-building activities
     

Combining kindness with wellness initiatives reinforces healthy workplace culture.

 

5. Random Acts of Kindness Challenge

Encourage employees to perform small acts such as:

  • Mentoring a junior colleague
     

  • Helping with workload
     

  • Writing appreciation emails
     

  • Sharing learning resources
     

Recognize participation at week’s end.

 

Kindness and Employee Retention

Studies consistently show that employees who feel recognized are more likely to remain loyal to their organizations.

Recognition contributes to:

  • Reduced turnover
     

  • Improved job satisfaction
     

  • Stronger commitment
     

  • Positive organizational citizenship behavior
     

Kindness Week may seem simple, but its long-term cultural impact can be significant.

 

Promoting Inclusivity During Kindness Week

Ensure recognition initiatives:

  • Avoid favoritism
     

  • Include all departments
     

  • Value non-managerial roles equally
     

  • Recognize behind-the-scenes contributions
     

Inclusivity strengthens fairness and trust.

 

Measuring the Impact

Organizations can assess the success of Kindness Week by tracking:

  • Employee feedback surveys
     

  • Participation rates
     

  • Team engagement metrics
     

  • Retention trends
     

Continuous appreciation initiatives beyond one week create sustainable results.

 

Building a Culture Beyond One Week

Kindness should not be limited to a single event. Companies can maintain momentum by:

  • Monthly recognition programs
     

  • Peer-to-peer appreciation platforms
     

  • Wellness check-ins
     

  • Leadership mentoring initiatives
     

Embedding appreciation into daily operations ensures lasting cultural transformation.

 

The Indian Corporate Context

In India’s rapidly growing corporate landscape, workplace stress and competition are increasing. Initiatives like Kindness Week support mental wellbeing, collaboration and emotional resilience.

Organizations prioritizing empathy and recognition often witness stronger teamwork and healthier work environments.

 

Conclusion

Kindness Week is more than a celebration — it is a strategic initiative to recognize employees who go the extra mile and foster a culture of appreciation. By encouraging empathy, gratitude and recognition, organizations create an environment where employees feel valued and motivated.

Simple acts of appreciation can lead to stronger teams, improved morale and long-term success. Recognizing kindness today builds a more collaborative and positive workplace for tomorrow.

 

References

  • Society for Human Resource Management – Employee Recognition Studies
  • Indian Journal of Occupational Health – Workplace Wellbeing Research
  • Harvard Business Review – Impact of Appreciation on Productivity
  • World Health Organization – Healthy Workplace Framework
  • National Institute of Mental Health – Workplace Mental Health Insights

See all

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