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Published on: Nov 13, 2020
1 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

Using The Cellular Handshake Against The Virus

Using the cellular handshake against the virus

In early November an interesting study was published in The Lancet Respiratory Medicine, describing the treatment of a severe COVID-19 patient with human recombinant soluble angiotensin-converting enzyme-2. By using the treatment, it was possible to see the disappearance of the virus swiftly from the patient's serum, nose, and lungs, as well as a reduction in the patients’ inflammatory markers. How was this achieved? And why is this so intriguing.

When we look at treating viruses, there are several strategies at work. You can prevent its spread by the use of social distancing or masks, you can use medications that prevent its replication (such as Tamiflu). Or you can stop the virus from entering the cells, the first step in viral replication.

SARS-CoV-2 appears to enter human cells through the ACE2 receptor. ACE2 is a protein in the cell membrane found across the human body, especially the lungs, heart, kidney and small intestine. It function is related to the Renin-Angiotensin System, a mechanism by which the kidneys control your blood pressure.

Angiotensin-Converting Enzyme converts angiotensin 1 to angiotensin 2, a hormone that causes blood vessels to constrict. ACE 2 instead converts it to a protein that causes dilation of blood vessels. This likely protects these critical organs and ensure they receive sufficient blood to perform their tasks. ACE2 is being investigated as a possible target for blood pressure medications.

The study used a genetically modified soluble form of ACE2 that mimics the protein found on human cell membranes. By increasing its availability in the blood, the SARS-CoV-2 virus binds to this protein, resulting in its inactivation, rather than entering lung cells and causing lung injury. Lab studies have shown that it can reduce viral growth by as much as 1000 to 5000 times, and phase 1 studies show it to be safe to use in people.

The actual described case was in a 45-year-old woman, hospitalized with COVID, suffering from severe shortness of breath, cough and fatigue. She was first treated with hydroxychloroquine and anticoagulants, but this proved ineffective, and the virus was causing increasing damage to her lungs. Nine days after her symptoms started, she received the ACE2 treatment for a week, with no side effects. This resulted in an increase in ACE2 activity (seen from her blood results), but also a marked decrease in multiple inflammatory markers associated with COVID-19, as well as a sharp decrease in COVID 19 numbers. Indeed, the viral load dropped from 32,000 per mL to just 270 per mL two days after treatment started. She was also able to produce antibodies against the virus, so this did not impair her from getting immunity.

It is certainly a very interesting case, though questions remain on how feasible it would be (as well as how expensive) to manufacture large quantities of this protein receptor for treatment use, as well as how it fairs in clinical trials.

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Virtual Cooking Class with Dietitian: A New Era of Healthy Eating in India

Healthy eating has become a top priority for individuals across India. With rising lifestyle diseases such as diabetes, hypertension, obesity and PCOS, food decisions now play a critical role in preventive healthcare. However, most people struggle with questions like what to cook, how to modify recipes, and how to balance nutrition with traditional Indian meals.

Virtual cooking classes with dietitians are transforming how Indians learn about food. They combine practical kitchen skills with scientific nutrition knowledge-something traditional cooking tutorials cannot offer. SecondMedic integrates expert dietitians, AI-driven nutrition analysis and preventive health frameworks to support individuals in building lifelong healthy eating habits.

This blog explores how virtual cooking classes work, why they matter and how they support long-term health.

Why India Needs Dietitian-Led Cooking Classes

Rising Lifestyle Diseases

The ICMR Nutrition and Metabolic Health Study reports alarming trends:

Over 100 million diabetic individuals
High prevalence of fatty liver
Vitamin deficiencies in large sections of the population
Increasing PCOS, thyroid disorders and obesity

Many of these conditions are strongly influenced by diet.

Lack of Nutrition Awareness

NFHS-5 highlights low dietary diversity among Indian households. People often overconsume oil, sugar and refined grains without realising the long-term impact.

Busy Lifestyles

Urban professionals struggle to plan meals due to:

Time constraints
Lack of structured nutrition knowledge
Dependence on takeaways and packaged food

Virtual cooking sessions solve these problems by offering guided, practical learning directly from home.

What Happens in a Virtual Cooking Class?

A SecondMedic virtual cooking class includes:

1. Live Demonstrations

Dietitians prepare recipes step-by-step while explaining:

Nutrient functions
Health benefits
Cooking techniques
Smart portion strategies

2. Ingredient Education

Participants learn about:

Low-GI alternatives
High-fibre grains
Clean protein sources
Anti-inflammatory spices
Healthy fats

3. Meal Planning Guidance

Classes often include weekly planning tips to simplify daily decisions.

4. Nutrient Breakdown

AI-based tools analyse the recipe’s:

Sugar load
Sodium balance
Protein density
Vitamin & mineral profile

5. Condition-Specific Variations

Recipes can be adapted for:

Diabetes
PCOS
Thyroid health
Heart health
Weight loss

This ensures suitability across lifestyles.

Benefits of Virtual Cooking Classes

1. Practical, Hands-On Learning

Participants cook alongside the dietitian, making learning interactive and easy to remember.

2. Prevention-Focused

Unlike regular cooking tutorials, these sessions emphasise preventive eating patterns recommended by WHO and NITI Aayog.

3. Customisable for Families

Healthy recipes become household-friendly, improving community nutrition.

4. Convenient and Accessible

Join from anywhere without travel or scheduling challenges.

5. Increases Long-Term Adherence

When people understand why a recipe is healthy, they adopt it more consistently.

Example Recipe Taught in Class

Vegetable Khichdi (Diabetes-Friendly Version):

Moong dal for high protein
Mixed vegetables for fibre
Minimal ghee
Brown rice/millet for lower GI
Turmeric + cumin for anti-inflammatory benefit

SecondMedic’s AI engine evaluates glycaemic impact and micronutrient density.

Integrating Virtual Cooking With Preventive Care

SecondMedic combines cooking classes with:

Teleconsultations
Diet assessments
AI nutrition scores
Weight and glucose monitoring
Lifestyle coaching

This creates a unified ecosystem for long-term behaviour change.

Conclusion

Virtual cooking classes with dietitians empower individuals to transform their daily meals into preventive healthcare tools. By teaching practical skills, nutrition fundamentals and personalised recipe adjustments, these classes make healthy eating accessible, enjoyable and sustainable.

SecondMedic is redefining preventive nutrition by blending expert guidance with digital interactivity and AI insights-helping people cook better, eat smarter and live healthier.

References

• ICMR Nutrition & Metabolic Health Study - Dietary Impact on Chronic Diseases
• National Family Health Survey (NFHS-5), Ministry of Health & Family Welfare
• NITI Aayog - Preventive Healthcare & Nutrition Strategy for India
• WHO Healthy Eating & Non-Communicable Disease Guidelines
• Lancet Public Health - Effectiveness of Lifestyle Interventions
• Statista India Digital Health & Online Learning Trends
• EY-FICCI Digital Nutrition & Virtual Wellness Report

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