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Published on: Apr 05, 2020
3 minute read
By: Dr Rajan Choudhary

Ventilators, When Breathing Is Not Enough For Covid-19 Patients!

Ventilators. A device few had heard of before the pandemic.

This life saving machine is desperately sought after by hospitals around the world. COVID patients with the most severe symptoms require ventilator support to survive and recover. But what is this machine? And what does it actually do?

THE BASICS

Breathing is a simple task, one that we do not think about. When we breathe our chest expands, and air is pulled into our lungs. Here oxygen is exchanged into the blood and transported by the pumping heart throughout the body. In our cells the oxygen is used to release energy from our food, and drive every process and reaction that keeps us alive and functioning.

COVID-19 is a respiratory disease caused by the coronavirus. Its symptoms include a dry cough, fever, feeling tired and more. In most patients the disease is mild. However some suffer from severe disease, causing havoc in their lungs. It can cause viral pneumonia in both of the patients lungs, which reduces the amount of lung able to bring in oxygen to the lung. The patient’s respiratory rate increases, as they struggle to draw in oxygen.

If a person is struggling to breathe on room air doctors can provide them extra oxygen. This is given through a mask they wear on their face. Normal air only has 21% oxygen, but in hospitals it is possible to give air that is 100% oxygen. This means more oxygen reaches the blood, and the patient has to put in less effort to breathe to get the same amount of oxygen to their cells.

In severe cases it can cause widespread inflammation in the lungs, causing fluid to build up and making breathing harder and more laborious. The patient can become tired having to breathe quicker and harder, and this is when doctors look to intensive care specialists and ventilator support.

VENTILATION

If a person is unable to breathe for themselves, it is possible to do this manually or mechanically. Specialists can insert a tube into the mouth of an unconscious patient that enters their windpipe. A bag pump can be attached to this, which a doctor can squeeze to push air into the patient’s lungs. But a person cannot continuously squeeze this bag to keep ventilating someone, as this is time consuming and tiring.

Ventilators are composed of a compressible reservoir or turbine that can push air into the patients lungs. Unlike regular pumps that continuously push air or water, ventilators have to mimic how we breathe. We inspire air in, then expire air out. Ventilators achieve this by pushing in air for a few seconds, inflating the lungs, then releasing the pressure. The natural elasticity of the patients ribs and lungs squeezes the excess air out, mimicking exhalation.

Modern ventilators are very smart, and have many configurable settings. They can be set to deliver defined quantities of air, change the rate of breathing and other advanced settings.

Hospitals regularly use ventilators for patients who are struggling to breathe, patients who are in a coma and have lost the ability to breathe, and also for anaesthetised patients in operating theatres. During the pandemic hospitals are cancelling unnecessary or non-emergency operations, redistributing these ventilators to be used for COVID patients instead.

MAKE MORE VENTS

It is estimated that up to 30% of patients that are admitted to hospital require ventilators. Most hospitals across the world do not have enough ventilators because they have never needed to ventilate so many patients. Governments have recruited the help of manufacturing companies to ramp up production of ventilators. In the UK F1 teams, military aircraft constructors and hoover manufacturers have all taken up the challenge and repurposed their factories.

There have also been innovations to create new ventilator designs that are cheap and easy to produce. This often involves off-the-shelf equipment that is already present in hospitals, and 3D printed parts. Such machines often do not require electricity or circuit board electronics, and can even be powered by the high pressure oxygen flowing from gas canisters or hospital walls.

- University College Dublin: https://techcrunch.com/2020/03/19/open-source-project-spins-up-3d-printed-ventilator-validation-prototype-in-just-one-week/ ventilator prototype

- University of Oxford: http://www.ox.ac.uk/news/2020-03-31-ventilator-project-oxvent-gets-green-light-uk-government-proceed-next-stage-testing Ventilator project

NEVER A SIMPLE SOLUTION

But as always its not always this simple. Ventilators are complex machines requiring specialist training to function and maintain, as ventilation and respiratory physiology is quite complicated. Ventilators will be of limited use if hospitals do not have enough staff trained to use them safely.

Ventilators are not without risk either. Because they push air into the lung, continuous use, excessive pressures and improper use can cause some damage to the delicate anatomy inside the lung, causing problems in itself. The plastic tube can also be a source of infection. Some hospitals that have had a sharp increase in ventilated patients have encountered problems supplying all their patients with pressurised oxygen. The patient load is overwhelming their infrastructure.

Unfortunately like most things in medicine, ventilators are not a magic cure. Due to the shortage of ventilators not everyone who needs one is able to get it. Most patients who end up needing ventilation are severely ill. The longer a person is on a ventilator the less likely they are to survive. This means that current mortality is rather high.

As more ventilators become available this treatment may become available to those with less severe symptoms, who are more likely to survive especially with this extra help. It is difficult to make these predictions because so many different variables can have an effect. For now we will have to wait and see.

WHAT DOES IT MEAN FOR ME?

The best way to help in these situations is by not catching the virus. This is especially true for those who are elderly, have diabetes, cardiovascular issues or lung diseases. These high-risk patients are more likely to have more serious symptoms, requiring hospitalization. This is why so many countries have enforced lockdown measures. The fewer that are infected, the fewer that need ventilation.

If you do need to leave the house, always follow the following procedures:

- Wash your hands regularly for 20 seconds with soap or alcohol

- Wear a mask outside: This is now official WHO policy

- If you need to cough or sneeze do so into your arm or a tissue

- Only leave the house for essential activities, shopping or to visit the doctor.

Dr Rajan Choudhary, Chief Product Officer & President, Second Medic UK

www.secondmedic.com

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Genetic Testing Services India: How DNA-Based Insights Are Transforming Preventive Healthcare

Genetic testing services in India have rapidly expanded over the last decade, becoming a vital part of preventive healthcare, early diagnosis, and personalized treatment planning. As medical science advances, understanding one’s DNA has become more accessible, accurate, and meaningful. Genetic testing empowers individuals with information about hereditary risks, potential health challenges, and personalized lifestyle recommendations based on their biological blueprint.

With rising chronic disease rates, cancer cases, and lifestyle-driven health issues, India is now embracing DNA-based healthcare as an essential tool for early detection and long-term prevention. SecondMedic integrates genetic insights into its preventive care ecosystem, helping individuals and families make informed decisions about their health.

The Growing Importance of Genetic Testing in India

India has a diverse population with complex genetic structures, making genetic testing particularly valuable. Many hereditary conditions often go undiagnosed until symptoms appear, which sometimes leads to delayed treatment.

Several factors are driving the growth of genetic testing in India:

Increased awareness of hereditary diseases
Rising cancer and cardiac risk among younger populations
Demand for preventive and precision healthcare
Wider availability of DNA-testing technology
Integration of genomics into clinical practice

As people seek more personalized healthcare, genetic testing has become a powerful tool for understanding risk factors long before they cause illness.

What Genetic Testing Reveals About Your Health

Genetic testing examines specific DNA markers to determine predispositions and inherited risks. The results provide clarity about future risks, potential conditions, and biological tendencies that influence long-term health.

Genetic testing can reveal:

Predisposition to cancer
Heart disease risk
Diabetes and metabolic disorders
Thyroid and hormonal disorders
Lipid metabolism issues
Neurological and genetic syndromes
Response to medicines (pharmacogenomics)
Carrier status for inheritable conditions

This information creates a foundation for preventive action, lifestyle modification, and informed medical decisions.

Types of Genetic Testing Available in India

India’s genetic testing ecosystem offers several categories of tests designed for different health needs.

Common types include:

Hereditary cancer risk testing
Cardiac risk genetic screening
Metabolic and lifestyle-based DNA tests
Carrier screening for inheritable conditions
Pharmacogenomic testing
Newborn screening
Whole exome or genome sequencing

SecondMedic works with leading genetic laboratories to deliver clinically validated tests integrated with actionable health insights.

Genetic Testing and Preventive Medicine

Preventive healthcare becomes far more effective when guided by genetic insights. Instead of waiting for symptoms, individuals can take proactive steps based on their specific risk profile.

Genetic testing supports preventive care by:

Identifying risks early
Recommending personalized diet and exercise plans
Providing medication compatibility insights
Monitoring high-risk individuals more closely
Guiding screening schedules

This approach significantly reduces the likelihood of severe disease progression.

Integration of Genetic Testing with Precision Medicine

Precision medicine aims to deliver treatments tailored to individual biology. Genetic testing is central to this approach, helping doctors customize care.

Genetic insights influence:

Selecting the right medications
Determining accurate dosages
Avoiding harmful drug reactions
Recommending targeted therapies
Planning long-term health strategies

SecondMedic combines genetic data with electronic health records, lab reports, and lifestyle assessments to build comprehensive care plans.

Genetic Testing and Family Health Management

Understanding genetic risks does not only benefit individuals—it supports entire families. Many conditions are passed down through generations and early awareness can help protect family members.

Genetic testing helps families identify:

Hereditary cancer patterns
Recessive or dominant genetic traits
Chromosomal conditions
Diseases likely to appear later in life

SecondMedic provides family-focused genetic counseling that helps relatives assess their own risks based on shared history.

Safety, Accuracy, and Reliability of Genetic Testing

Modern genetic testing is safe, non-invasive, and highly reliable. Most tests require only a saliva sample or a painless cheek swab. Laboratories then analyze DNA using advanced sequencing technologies.

Accuracy is ensured through:

Globally validated testing panels
High-depth DNA sequencing
Cross-verified genetic markers
Clinically certified laboratories
Medical review of results

SecondMedic ensures that genetic reports are interpreted by certified experts for practical application.

The Role of Genetic Counseling in DNA-Based Healthcare

Raw DNA data alone is not enough. Patients need clear guidance on how to understand and apply genetic results. Genetic counseling helps individuals navigate results confidently and make informed decisions.

Counseling includes:

Explanation of risk levels
Genetic pattern interpretation
Clear preventive recommendations
Family planning guidance
Personalized lifestyle strategies

SecondMedic offers genetic counseling alongside reports to ensure meaningful, actionable insights.

How SecondMedic Integrates Genetic Testing into Preventive Care

SecondMedic creates a seamless experience where genetic testing becomes part of a broader health management plan. After receiving results, individuals gain access to personalized nutrition, fitness, screening schedules, and digital monitoring tools.

SecondMedic’s approach includes:

Personalized DNA-based health reports
Doctor-reviewed insights
Custom preventive health plans
Ongoing monitoring and follow-up
Integration with AI-based risk scoring
Virtual consultations with specialists

This ensures long-term support based on accurate genetic understanding.

The Future of Genetic Testing in India

Genomics is set to transform Indian healthcare in the coming years. As technology becomes more affordable and awareness grows, genetic testing will become a routine part of preventive health.

Upcoming trends include:

Widespread use of pharmacogenomics
DNA-based nutrition personalization
Expanded newborn genetic screening
AI-driven genetic interpretation
Integration with national digital health records
Genetic-based early disease prediction

SecondMedic aims to make genetic testing accessible, affordable, and clinically meaningful for individuals across India.

Conclusion

Genetic testing services in India are unlocking powerful insights that empower individuals to take control of their health. Through DNA-based risk assessment, hereditary screening, and precision medicine, genetic testing creates a pathway to informed, preventive, and personalized healthcare. SecondMedic integrates these insights into comprehensive wellness plans, giving users long-term guidance for healthier living.

To book genetic testing or explore DNA-based health programs, visit www.secondmedic.com

References

NITI Aayog – Genomics and Precision Medicine India
ICMR – Genetic Disorders in India 2024
IMARC – Indian Genetic Testing Market Report
WHO – Human Genomics in Healthcare
Nature Genetics – Global Genetic Risk Studies

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