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Published on: Nov 13, 2020
2 minute read
By: Dr Rajan ( Medical Second Opinion Cell)

What Are Some Common Side Effects Of The COVID-19 Vaccine?

COVID Vaccine, the Pfizer update

On Monday Pfizer announced to the world the vaccine, once it has been developing with Germany's BioNTech, was found to be more than 90?fective. If this is substantiated, it may be possible for countries to receive the vaccine before the end of the year.

The Vaccine is an mRNA Vaccine, a novel method that introduces viral RNA into the body via a viral coat. The vaccine is incorporated into the person's cell, where the viral RNA is read and viral proteins are produced, including the coronavirus coat proteins. As the body reads and recognizes these proteins, it produces antibodies against these viral proteins and activates immune T cells against the virus.

The Pfizer results are based of a phase 3 clinical trial with 43, 538 participants with a diverse background. In this trial, the participants were split between those receiving a vaccine, and those who received a placebo with no effect. The vaccine is administered in two parts, with a 90?ficacy obtained 7 days after the second dose. This would mean a person is vaccinated just 28 days after the initial vaccination.

The FDA usually looks for a minimum 50?ficacy in vaccination when approving new vaccines. It may surprise you that the annual flu jab is also estimated to be 50?fective. The data from Pfizer was verified by an external, independent Data Monitoring Committee. It used data from 94 patients enrolled in the trial and subsequently developed COVID. It is from this groupset that 90% of efficacy is obtained. This is not the final data analysis, and further publications are expected in late November, with a potential FDA Emergency Use Authorisation approval if the data continues to show promise.

If approved, Pfizer has the ability to make 50 million shots before the end of the year, and 1.3 billion by the end of 2021. Many countries are clamoring for their fair share of these limited resources; the US has already negotiated 200m shots, UK 50m, and Germany (one of the major financers for the Pfizer vaccine) over 300m for European Countries.

We should emphasize that rapid vaccine development on this scale at this speed was unheard of prior to COVID. Usually, the animal studies for vaccines can take 1-2 years. In that time Pfizer and others have managed phase 1-3 clinical trials in humans, something that usually takes upwards of 10 years.

There are many unanswered questions that remain from this information.

How safe is the vaccine? Whilst safety information was not published, overall the vaccine appears to have minimal side effects. This is particularly difficult to state however since mRNA vaccines have never been used in people before.
Does the vaccine prevent transmission? In theory, yes. If you are immunized the replication of the virus should be limited significantly, so the number of viruses in each cough will be much lower. However, we do not have data to prove that there is no transmission, but that is also because we have very little data overall.
How long does the protection last? This is a very critical question. The 90?fectiveness rate was calculated just 7 days after the second shot, but it is likely this will change as data is collected over the long term. Some studies have suggested the antibody response fades within months following COVID infection. T Cell immunity on the other hand can stay for years, and it may be the effectiveness of creating a T cell immunity that dictates just how good this vaccine will be .

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Why Do You Wake Up Tired Even After 8 Hours Sleep?

Getting 8 hours of sleep is often seen as the gold standard for good health. But what if you’re still waking up feeling groggy, exhausted, and low on energy—despite clocking in those 8 hours? If that sounds like you, you’re not alone.

In this blog, we’ll explore why you wake up tired even after 8 hours sleep, the possible reasons behind it, and simple ways to fix the issue so you can start your day refreshed and energized.

Sleep Quantity vs. Sleep Quality

It’s important to understand that sleep is not just about how long you sleep, but how well you sleep.

There are different stages of sleep your body goes through:

Light Sleep (Stage 1 & 2)
Deep Sleep (Stage 3)
REM Sleep (Stage 4) – where dreams and memory processing happen

If your sleep is constantly interrupted, or if you don’t get enough deep or REM sleep, your body and brain won’t be fully rested—even after 8 hours in bed.

7 Common Reasons You Wake Up Tired After a Full Night’s Sleep

1. Poor Sleep Quality

You may be lying in bed for 8 hours, but if your sleep is light or frequently interrupted, it won’t be refreshing. Common reasons include:

Noisy environment
Uncomfortable mattress or pillow
Room too hot or too cold
Lights or electronics nearby

Fix: Try blackout curtains, keep the room cool and dark, and follow a fixed bedtime routine.

2. Undiagnosed Sleep Disorders

Conditions like sleep apnea, restless leg syndrome, or insomnia can reduce sleep quality without you even realizing it.

Sleep apnea, for example, causes you to stop breathing for short periods during sleep. You may not wake up fully, but your body doesn’t get enough oxygen—leading to morning tiredness and brain fog.

Fix: If your partner says you snore heavily or you often wake up gasping for air, consult a doctor for a sleep study.

3. Too Much Screen Time at Night

Smartphones, laptops, and TVs emit blue light, which blocks melatonin—a hormone that helps you fall asleep.

If you scroll Instagram or binge-watch shows late at night, your brain might stay active even after you fall asleep.

Fix: Stop using screens 1 hour before bedtime. Use night mode or blue light filters if necessary.

4. Eating or Drinking Close to Bedtime

Heavy meals or caffeine before bed can disturb your sleep by causing indigestion, bloating, or increased alertness.

Fix: Avoid caffeine after 5 PM, and try to have your dinner at least 2 hours before sleeping.

5. Mental Health Issues

Conditions like stress, anxiety, or depression can impact sleep quality. You may sleep for hours but still wake up tired due to mental fatigue.

Fix: Practice stress management through:

Journaling
Breathing exercises
Meditation
Seeking therapy if needed

6. Vitamin or Hormonal Imbalance

Low levels of Vitamin D, Vitamin B12, iron, or thyroid dysfunction can cause constant fatigue—even with good sleep.

Fix: A simple blood test can help detect deficiencies. You can book these tests via SecondMedic.com, powered by Thyrocare, with home sample collection.

Recommended tests:

Vitamin D Test
Vitamin B12
Thyroid Profile
CBC (Complete Blood Count)

7. Lack of Physical Activity

Not moving your body enough during the day can lead to low-quality sleep at night. Exercise helps burn excess energy and improves deep sleep.

Fix: Aim for at least 30 minutes of physical activity, like walking, yoga, or cycling daily.

Signs That You’re Not Getting Good Sleep

You hit the snooze button multiple times
You feel sleepy by mid-morning
You wake up with a heavy head or sore body
You need coffee immediately to function
You feel irritated, anxious, or unmotivated

These are signs your body is not truly rested.

Simple Tips for Better Sleep & Morning Energy

Stick to a sleep schedule: Go to bed and wake up at the same time every day—even on weekends.
Create a sleep-friendly space: Keep your bedroom cool, quiet, and dark.
Limit naps: Daytime naps should be less than 30 minutes and before 3 PM.
Stay hydrated—but not too close to bedtime: Drinking too much water late may wake you up to pee.
Practice relaxation before bed: Try reading, light stretching, or herbal tea.

Conclusion

Feeling tired despite getting enough sleep can be frustrating. But remember, quality beats quantity when it comes to sleep. By making small changes in your routine, checking for hidden health issues, and improving your lifestyle, you can wake up feeling refreshed and ready to take on the day.

If you’ve been wondering why do you wake up tired even after 8 hours sleep, now you know where to start fixing it. Begin today with a better sleep routine—and better mornings will follow.

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