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Published on: Aug 03, 2021
2 minute read
By: Second Medic Pulmonologist

What Is Mucormycosis & COVID-19 Associated With Mucormycosis ?

Mucormycosis is a rare but serious infectious disease that can be caused by inhaling spores from the ubiquitous fungi. These organisms, commonly found in soil and composts are also present on fallen leaves or animal dung. Less contagious than other types of infections, mucormycosis mainly affects people who have weakened immune systems because it cannot spread like others that do not need an outside source to enter one's body via open wounds or cuts. Mucoromyces mean "fuzz," which describes their appearance when seen under a microscope with long branching filaments called pseudohistiocysts arising off these branched threads (hyphae).

Mucormycosis is a rare but serious angio-invasive infection caused by ubiquitous fungi. The spores of these fungi can be inhaled and then infect the lungs, sinuses, or extend into brain tissue to cause mucormycosis in people who are immunocompromised. Mucoromyces has been found all over Earth with it mainly affecting those living on farms due to contact from animal dung containing high quantities of this fungus type as well as compost piles where fresh manure falls leaves cover vegetable gardening beds that may have fallen nearby leading most cases occurring near woodland areas such before dorms at college campuses were previously thought responsible for respiratory infections since they might contain bacteria like tuberculosis which also needs oxygenated.

Fungal infections, including mucormycosis, aspergillosis and invasive candidiasis, have been reported in patients with severe COVID-19 or those recovering from the disease and are associated with a high risk of serious illness. India has recently seen an increase in cases that present this way when compared to other countries where these types of fungus thrive. Prevention needs to focus on making sure people who suffer from Covid-19 maintain better glycemic control so they do not develop any fungal infection like Mucoromyces Cerealis (a subtype found more often outside India) which can cause pneumonia if untreated or brain damage if left too long without treatment because it is resistant both systemic corticosteroids/other.

Mucormycosis, an invasive fungal infection that can lead to death, has been reported in patients with severe COVID-19. The Indian government recently noted a surge of cases and the spread of this dangerous condition is attributed largely to poor glycemic control among those living with the disease or recovering from it.

Fungal infections, including mucormycosis and invasive candidiasis, have been reported in patients with severe COVID-19 or those recovering from the disease. India has seen an uptick of cases due to fungal infection caused by COVID-19 along with a surge in people who are severely affected because they were not diagnosed early on while fighting off the virus. Prevention for this type of fungus is increased monitoring when trying to apply systemic corticosteroids/other immunomodulating drugs on these patients just as much as it would be if there was no sign that someone had ARDS (acute respiratory distress syndrome).

Mucormycosis is not contagious and does not spread by contact from person to person. This fungus has been found in the environment, but transmission occurs through inhalation or ingestion of spores from the environment. Although most cases are sporadic, healthcare-associated outbreaks have occurred after the use of adhesive bandages made out wood tongue depressors as well as linens with lackadaisical hygiene standards at hospitals that result in fungal exposure on surfaces like walls and floors which can lead to airborne infection if those areas aren't properly cleaned up soon enough. Mucormicosis primarily affects sinuses or lungs after inhaling spores from air when it's breathed directly into them.

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Shortness of Breath Causes: From Common Triggers to Serious Health Conditions

Shortness of breath, medically known as dyspnea, is a symptom that ranges from mild discomfort during exertion to a distressing sensation of not getting enough air. In India, increasing air pollution, lifestyle diseases and respiratory infections have made breathlessness a frequent complaint across age groups. Understanding shortness of breath causes is essential to identify when it is harmless and when it signals a medical emergency.

What Is Shortness of Breath?

Shortness of breath refers to difficulty breathing or a feeling of air hunger.

It may present as:

rapid breathing
shallow breathing
tightness in the chest
inability to take a deep breath

The sensation can develop suddenly or gradually.

Common and Benign Causes of Shortness of Breath

Physical Exertion

During exercise, the body demands more oxygen.

Temporary breathlessness during:

climbing stairs
running
heavy physical work

is normal and resolves with rest.

Anxiety and Panic Attacks

Stress and anxiety alter breathing patterns.

Symptoms include:

rapid breathing
chest tightness
dizziness

These episodes often resolve with calming techniques.

Respiratory Causes of Shortness of Breath

Asthma

Asthma causes airway narrowing and inflammation.

Symptoms include:

wheezing
chest tightness
breathlessness during exertion or at night

Asthma is a leading cause of chronic breathlessness.

Chronic Obstructive Pulmonary Disease

COPD includes chronic bronchitis and emphysema.

Risk factors include:

smoking
indoor air pollution
occupational exposure

WHO identifies COPD as a major cause of breathlessness in adults.

Respiratory Infections

Infections such as pneumonia and bronchitis reduce lung capacity.

Breathlessness may be accompanied by:

cough
fever
chest pain

Severe infections require urgent treatment.

Heart-Related Causes of Shortness of Breath

Heart Failure

The heart fails to pump blood efficiently.

This leads to:

fluid accumulation in lungs
breathlessness on exertion
breathlessness while lying flat

ICMR data shows heart disease as a major contributor to unexplained breathlessness.

Coronary Artery Disease

Reduced blood supply to the heart can cause:

breathlessness
chest discomfort
fatigue

This may occur even without chest pain in some individuals.

Blood and Metabolic Causes

Anemia

Low hemoglobin reduces oxygen delivery.

Common symptoms include:

fatigue
breathlessness on mild activity
pale skin

NFHS-5 highlights anemia as highly prevalent in India.

Thyroid Disorders

Hyperthyroidism increases metabolic demand, causing breathlessness.

Hypothyroidism may contribute indirectly through weight gain and reduced stamina.

Lung Circulation Disorders

Pulmonary Embolism

A blood clot in the lungs causes sudden, severe breathlessness.

This is a medical emergency and may be accompanied by:

chest pain
coughing blood
fainting

Immediate treatment is critical.

Lifestyle-Related Causes

Obesity

Excess body weight restricts lung expansion.

Breathlessness occurs due to:

increased oxygen demand
reduced lung volumes

Weight management improves breathing efficiency.

Sedentary Lifestyle

Poor physical conditioning reduces respiratory muscle strength.

Even mild exertion may cause breathlessness.

Environmental and Occupational Factors

Air Pollution

Pollutants irritate airways and reduce lung function.

Urban populations experience higher rates of breathlessness.

Workplace Exposure

Dust, chemicals and fumes increase respiratory risk.

Protective measures are essential in high-risk occupations.

When Shortness of Breath Is a Warning Sign

Seek urgent care if breathlessness:

starts suddenly
worsens rapidly
occurs at rest
is associated with chest pain, bluish lips or confusion

These may indicate life-threatening conditions.

How Shortness of Breath Is Diagnosed

Evaluation may include:

physical examination
chest imaging
blood tests
lung function tests
heart evaluation

Diagnosis focuses on identifying the root cause.

Preventive Measures and Lifestyle Care

Prevention includes:

regular physical activity
pollution protection
smoking cessation
weight control
managing chronic conditions

Preventive healthcare reduces long-term risk.

Importance of Early Medical Evaluation

Delayed diagnosis can worsen outcomes, especially in:

heart disease
lung infections
anemia

Early care improves treatment success.

Conclusion

Shortness of breath causes range from temporary exertion and anxiety to serious heart, lung and blood disorders. While occasional breathlessness may be harmless, persistent or sudden symptoms should never be ignored. Understanding the underlying causes and seeking timely medical evaluation can prevent complications and save lives. Paying attention to changes in breathing is an essential step toward protecting overall health and wellbeing.

References

Indian Council of Medical Research (ICMR) – Respiratory and Cardiac Health Reports
World Health Organization (WHO) – Breathlessness and Chronic Disease Guidelines
National Family Health Survey (NFHS-5) – Anemia and Respiratory Health Data
Lancet – Dyspnea Evaluation and Outcomes Research
NITI Aayog – Non-Communicable Disease Prevention Reports
Statista – Respiratory Disease and Air Pollution Trends

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