• Published on: Sep 26, 2021
  • 3 minute read
  • By: Second Medic Expert

What Is The Meaning Of Pre-diabetic?

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What is the meaning of pre-diabetic?

Pre-diabetes is the stage that comes before type 2 diabetes. If blood sugar levels are high but not yet high enough to be classified as type 2 diabetes, then you are pre-diabetic.

A person may have pre-diabetes if they find it hard to control their blood glucose levels.

It is important to note how long you have had this condition and what your other risk factors are like such as age, history of gestational diabetes, history of cardiovascular disease, family history (genetic heritability), obesity (BMI > 30), physical inactivity.

Pre-diabetic people tend to be insulin resistant or sensitive when they're not eating anything, and the fasting level is high at 138 mg/dl and when they're drinking glucose their fasting level goes up even more and after a meal, their blood sugar goes up higher than 140 mg/dl at least two times in 225.

Someone affected by pre-diabetes has an impaired ability to produce insulin, which is necessary to regulate glucose levels. This could lead to high blood sugar over time. People who are pre-diabetic may suffer from polycystic ovary syndrome (PCOS), normal aging or another illness that causes the pancreas to fail to work properly. A person suffering from pre-diabetes is suffering from high blood sugar levels. A person suffering from diabetes not Type 1 is suffering from high blood sugar levels.

Sometimes people are diagnosed with pre-diabetes instead of Type II Diabetes because it's more common in the population. Pre-diabetes occurs when the body cannot produce enough insulin or process glucose properly to regulate blood sugar, but that can be managed through diet and exercise in most cases.

Type I Diabetes is when a person cannot make any insulin at all, whereas type II might be caused by, for example, an unfortunate metabolic issue or lifestyle change like eating too many sweets or quitting smoking.

Pre-diabetic refers to a person who has blood sugar levels that qualify him or her as "pre-high blood glucose" but not high enough to be considered diabetic yet. Pre-diabetes is a temporary condition in which the body starts to develop insulin resistance, and the cells of your pancreas start secreting more and more of their own insulin to avoid producing too much glucose. Eventually, this becomes counterproductive, the pancreas becomes so resistant it can't keep up with demand anymore, and type 2 diabetes occurs. However, pre-diabetes does not require any treatment because by avoiding junk food and excessive portions (and exercising) you will likely get off pre-diabetics without ever developing diabetes. Pre-diabetes is a term to describe high blood insulin levels that are on the cusp of developing type 2 diabetes but haven't yet.

Type 2 diabetes develops when cells lose their insulin receptors and cannot create enough sugar for themselves. This means the body has to produce more and more insulin in order to get glucose into any cells with remaining insulin receptors (such as muscle or fat cells). Over time, high levels of circulating hormones lead to damage in the small vessels that provide oxygen and nutrients — particularly to kidneys — putting them at risk of failure. This can happen over decades and is referred to as "insulin resistance".

The primary goal for people suffering from pre-diabetes should be lifestyle change: reduce weight. Pre-diabetic means that you are at high risk for developing type 2 diabetes. If you're overweight, have a family history of diabetes, develop gestational diabetes while pregnant, or if it runs in your household then pre-diabetes is more likely to progress into type 2 diabetes.

Pre-diabetic means that a patient has been diagnosed as prediabetic – that is, their blood sugar levels are higher than normal but not yet high enough to be classified as having diabetes. People with pre-diabetes have a greatly increased risk of developing type 2 diabetes and cardiovascular disease. One study found that adults who had one or more characteristics of the metabolic syndrome exhibited a 46% reduction in risk for the development of diabetes over 4 years following blinded diagnosis if they took metformin therapy alone or with other agents, compared to those on placebo therapy. In addition, people with pre-metabolic syndrome specifically were found to have 89?creased risks for this development

The term pre-diabetic is typically applied to patients who have impaired glucose tolerance or who are at risk for developing type 2 diabetes. A patient is considered a pre-diabetic when he or she has high blood sugar levels that may lead to progression into full-blown diabetes, called Type 2 Diabetes Mellitus, but doesn't meet the diagnostic criteria for T2DM. In other words, the cells of this patient's body aren't quite as dysfunctional as those of a diabetic, yet they show signs of dysfunction. This stage falls between normal and diabetic and is sometimes referred to as prediabetes because it puts an individual at "risk" for T2DM development.

A pre-diabetic person is one who exhibits signs that they may be diabetic. The symptoms include stomach pains, frequent urination, and sudden weight loss. Pre-diabetes used to be known as age-related diabetes and are common in adults who are overweight and have high blood pressure or abnormal cholesterol levels. Early-onset of pre-diabetes can lead to both short-term and long-term risks including heart disease, strokes, kidney failure, blindness caused by diabetic retinopathy (Eye) as well as early death for people with type 2 diabetes.

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Guillain-Barre syndrome - Symptoms and causes

Guillain-Barre syndrome - Symptoms and causes

Guillain-Barré syndrome (GBS) is a rare but serious neurological condition in which the body’s immune system mistakenly attacks the peripheral nervous system. This condition can lead to muscle weakness, numbness, and even paralysis in severe cases. Understanding Guillain-Barré syndrome symptoms, causes, and treatment options is crucial for early detection and effective management.

Guillain-Barré Syndrome Symptoms

The symptoms of Guillain-Barré syndrome typically begin with mild sensations of tingling or numbness in the hands and feet. These early signs of Guillain-Barré syndrome may quickly progress to more severe issues, including:

  • Muscle Weakness: Starting in the legs and spreading to the upper body, this weakness can become so severe that mobility is significantly impaired.

  • Reflex Loss: Deep tendon reflexes, such as the knee-jerk response, are often diminished or absent.

  • Pain: Many individuals experience sharp or cramping pain, particularly in the lower back.

  • Difficulty with Eye or Facial Movements: Symptoms may include difficulty speaking, chewing, or swallowing.

  • Respiratory Problems: In some cases, Guillain-Barré syndrome and respiratory failure become significant concerns, necessitating immediate medical intervention.

  • Autonomic Dysfunction: Irregular heart rhythms, blood pressure fluctuations, and other involuntary functions can be affected.

Guillain-Barré Syndrome Causes

The exact causes of Guillain-Barré syndrome are not fully understood. However, it is widely believed that the syndrome is triggered by an overactive immune response to an infection or other environmental factors. Common Guillain-Barré syndrome causes and risk factors include:

  • Viral Infections: Conditions such as influenza, Zika virus, and Epstein-Barr virus have been associated with GBS.

  • Bacterial Infections: Campylobacter jejuni, a bacterium often linked to food poisoning, is a common trigger.

  • Vaccinations: Although extremely rare, certain vaccines have been linked to GBS.

  • Surgical Procedures: Some individuals may develop Guillain-Barré syndrome following surgery.

  • Other Risk Factors: A history of autoimmune disorders or genetic predispositions may increase the risk.

Guillain-Barré Syndrome Progression Stages

Guillain-Barré syndrome progression stages typically unfold in three distinct phases:

  1. Initial Stage: Lasting 1-4 weeks, this stage includes the rapid onset of Guillain-Barré syndrome symptoms such as weakness and numbness.

  2. Plateau Stage: Symptoms stabilize but remain severe. This stage can last several weeks.

  3. Recovery Stage: Gradual improvement begins, although Guillain-Barré syndrome recovery time can vary significantly between individuals, often taking weeks to months.

Guillain-Barré Syndrome Diagnosis

Diagnosing Guillain-Barré syndrome requires a thorough clinical evaluation. Physicians rely on specific Guillain-Barré syndrome diagnosis criteria, which include:

  • Patient History: Recent infections or medical procedures may provide crucial clues.

  • Neurological Examination: Reflexes, muscle strength, and sensory responses are assessed.

  • Electrodiagnostic Tests: Nerve conduction studies (NCS) and electromyography (EMG) help identify nerve damage.

  • Lumbar Puncture: Testing cerebrospinal fluid (CSF) can reveal elevated protein levels, a hallmark of GBS.

Early diagnosis is essential for effective treatment and to prevent complications like Guillain-Barré syndrome and respiratory failure.

Guillain-Barré Syndrome Treatment

Treatment for Guillain-Barré syndrome focuses on managing symptoms and speeding up recovery. The primary Guillain-Barré syndrome treatment options include:

  • Plasma Exchange (Plasmapheresis): This procedure removes harmful antibodies from the blood.

  • Intravenous Immunoglobulin (IVIG): High-dose immunoglobulin therapy helps neutralize the antibodies attacking the nervous system.

  • Supportive Care: Ventilatory support may be needed in severe cases, along with physical therapy to aid rehabilitation.

Guillain-Barré Syndrome Prognosis

The prognosis for Guillain-Barré syndrome varies depending on the severity of the condition and the timeliness of treatment. While most individuals recover fully, Guillain-Barré syndrome prognosis can include long-term complications such as:

  • Persistent Weakness: Some patients may experience lingering muscle weakness.

  • Nerve Damage: Chronic nerve pain or numbness can occur in rare cases.

  • Recurrence: Although uncommon, some individuals may develop Guillain-Barré syndrome again.

Guillain-Barré Syndrome Recovery Time

Guillain-Barré syndrome recovery time can range from a few weeks to several months. Factors that influence recovery include:

  • Age: Younger individuals generally recover faster.

  • Severity: Severe cases with extensive nerve damage may take longer to heal.

  • Timely Treatment: Early intervention is key to minimizing long-term effects and shortening recovery time.

Conclusion

Guillain-Barré syndrome is a challenging condition that requires early recognition and prompt treatment. By understanding the symptoms, causes, and treatment options, individuals can better manage this syndrome and improve their outcomes. If you or a loved one suspect Guillain-Barré syndrome, consult a healthcare professional immediately. Early diagnosis and treatment are critical for a full recovery.

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