• Published on: Jul 29, 2021
  • 2 minute read
  • By: Raj Dwivedi

What Tests Are Used To Manage Anemia And What Do They Mean?

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The doctors use a number of tests to diagnose anemia. Hb (hemoglobin) is one of the key indicators used in diagnosis. A hemoglobin test is a blood test that measures how much hemoglobin you have in your red blood cells. A hemoglobin test is generally used for detecting:

In addition, a hemoglobin test can also be carried out to assess bone marrow's response to treatment, evaluate possible blood donation and check the levels of red blood cells in the body. There are certain conditions that may interfere with the results of the hemoglobin test. In such cases, it is recommended to get the test done again.

For the hemoglobin test, a sample of your blood is taken and tested in a clinical laboratory [read more about the process here]. The results are expressed as grams of hemoglobin per deciliter (g/dL) or micrograms per liter (mcg/L). Normal range for this test is 12g/dL - 18g/dL (12.1-18.0 g/L) for adults and 9g/dL - 13g/dL (9.0-13.3 g/L) for children. If the test result comes out to be less than 7 gm, it can indicate a serious condition known as severe anemia. In some cases, the doctors may order follow-up tests to assess the current condition of the patient.

Apart from the hemoglobin test, certain other blood tests can be used for detecting low RBCs (RBC count) or abnormal types of RBC (red cell indices) or hemoglobin (Hb). These include complete blood count tests, reticulocyte tests, iron tests, and red blood cell indices.

In some cases, the doctor may opt to do a bone marrow aspiration and exam to check for any abnormalities in the bone marrow cells. In such cases, it of red blood cells is karyotype to rule out chromosomal disorders.

The most common reason for having an inadequate number of red blood cells in the body is an iron deficiency or anemia. Iron plays a significant role in the production of hemoglobin, which is responsible for carrying oxygen from the lungs to the tissues of other parts of the body. Hence, people suffering from iron are known as sickle cell trait. The tests include:

Complete blood count test - The complete blood cell count (CBC) is a routine test that checks the different components of your blood like number of red blood cells, white blood cells and platelets. It also has information about the size and hemoglobin content in each of these cells. A CBC includes tests for the following:

Reticulocyte test - This is a blood test that measures the reticulocytes (immature red blood cells) in the bloodstream. A high level of reticulocytes can indicate increased production of red blood cells by the bone marrow to compensate for anemia, or destruction of very early stage RBCs which are still unable to mature.

Iron tests - Iron is an essential component for RBC production. A test to assess the iron level in your blood is called a serum ferritin test, which measures the amount of iron stored in the body's cells and tissues. Another way to evaluate low iron levels is by carrying out a transferrin saturation test. In this case, the lab technician will extract serum from your blood sample and measure the amount of transferrin protein present in it. Transferrin is a protein that carries iron to the bone marrow where red blood cells are produced. Thus, if there is an insufficient amount of transferrin protein present in the serum, it shows that there is an inadequate level of stored iron.

Hemoglobin tests - A hemoglobin test is generally carried out to detect anemia, especially if the result of CBC tests are inconclusive. During this test, a small sample of blood is collected from your vein and sent to the laboratory for analysis. The test measures the amount of hemoglobin in your red blood cells.

Red cell indices - Red cell indices are tests that measure the size and hemoglobin content of the red blood cells. The values obtained from these tests can be used to detect anemia and other blood disorders.

Karyotype test - It is a lab test used to evaluate chromosomal abnormalities in red blood cells or bone marrow cells

Low blood cell counts also have other causes, such as infections or tumors. In some cases, low blood cells may indicate a more serious condition like bone marrow failure which requires immediate medical intervention to save the patient from death.

Thus, if you are suffering from any of these conditions and symptoms and suspect that you may be anemic, check with your doctor for the necessary tests to confirm or rule out your suspicions. Early detection and treatment of anemia can save you from serious complications like heart attacks, strokes, blood clots, etc.

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Tuberculosis

Tuberculosis Symptoms and Treatment: Early Signs, Diagnosis, and Recovery

Tuberculosis (TB) is one of the oldest known infectious diseases and continues to be a major public health concern, especially in developing countries. India accounts for a significant proportion of global TB cases, despite advances in diagnosis and treatment. The good news is that tuberculosis is preventable, treatable and curable when detected early and managed properly.

Understanding tuberculosis symptoms and treatment is critical for reducing disease spread, preventing complications and achieving complete recovery.

 

What Is Tuberculosis?

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. It primarily affects the lungs (pulmonary TB) but can also involve other parts of the body such as:

  • lymph nodes
     

  • bones and joints
     

  • kidneys
     

  • brain
     

TB spreads through the air when an infected person coughs, sneezes or speaks.

 

Why Tuberculosis Remains a Major Health Issue

According to the World Health Organization and ICMR data:

  • millions of new TB cases are reported annually
     

  • delayed diagnosis increases transmission
     

  • incomplete treatment leads to drug resistance
     

Early detection and treatment are key to TB control.

 

Common Tuberculosis Symptoms

TB symptoms often develop gradually and may be mild in the early stages, leading to delayed diagnosis.

Persistent Cough

A cough lasting more than two to three weeks is a hallmark symptom of pulmonary TB.

The cough may:

  • be dry or productive
     

  • worsen over time
     

  • sometimes produce blood
     

 

Fever and Night Sweats

Low-grade fever, especially in the evenings, is common.

Night sweats that soak clothing or bedding are a classic TB sign.

 

Unexplained Weight Loss

TB increases metabolic demand and reduces appetite, leading to significant weight loss.

 

Fatigue and Weakness

Persistent tiredness and reduced stamina occur due to chronic infection.

 

Chest Pain

Chest discomfort or pain may occur during coughing or breathing.

 

Symptoms of Extra-Pulmonary TB

When TB affects organs outside the lungs, symptoms depend on the site involved and may include:

  • swollen lymph nodes
     

  • bone or joint pain
     

  • headaches or neurological symptoms
     

  • urinary issues
     

 

Why TB Symptoms Are Often Ignored

Many TB symptoms resemble common infections or general weakness.

This leads to:

  • delayed medical consultation
     

  • prolonged transmission
     

  • disease progression
     

Awareness improves early detection.

 

How Tuberculosis Is Diagnosed

Diagnosis involves a combination of:

  • sputum tests
     

  • chest X-ray
     

  • molecular tests such as CBNAAT
     

  • blood tests and imaging for extra-pulmonary TB
     

Early and accurate diagnosis is essential for effective treatment.

 

Tuberculosis Treatment Explained

TB treatment involves a combination of antibiotics taken over a fixed duration.

Standard TB Treatment

For drug-sensitive TB, treatment typically lasts:

  • 6 months
     

The regimen includes multiple antibiotics taken in phases to ensure complete bacterial clearance.

 

Importance of Treatment Adherence

TB bacteria are slow-growing and resilient.

Stopping treatment early can result in:

  • incomplete cure
     

  • relapse
     

  • drug-resistant TB
     

Completing the full course is essential.

 

Drug-Resistant TB

If TB bacteria become resistant to standard drugs, treatment becomes longer and more complex.

Drug-resistant TB requires:

  • specialised medications
     

  • longer treatment duration
     

  • close medical supervision
     

Prevention of resistance depends on correct treatment from the start.

 

Side Effects of TB Treatment

Some individuals may experience side effects such as:

  • nausea
     

  • loss of appetite
     

  • mild liver enzyme changes
     

Most side effects are manageable with medical guidance and do not require stopping treatment.

 

TB and Public Health

TB is not just an individual health issue but a community concern.

Effective TB control requires:

  • early diagnosis
     

  • treatment adherence
     

  • contact tracing
     

  • public awareness
     

India’s national TB elimination programmes focus on these strategies.

 

Preventing Tuberculosis

Preventive measures include:

  • early detection and treatment of active TB
     

  • improving nutrition and immunity
     

  • adequate ventilation in living spaces
     

  • screening close contacts
     

BCG vaccination offers partial protection, especially in children.

 

Living With and Recovering From TB

With proper treatment:

  • symptoms gradually improve
     

  • infection becomes non-contagious
     

  • normal life can be resumed
     

Regular follow-up ensures complete recovery.

 

When to Seek Medical Help

Consult a healthcare provider if experiencing:

  • cough lasting more than two weeks
     

  • unexplained weight loss
     

  • persistent fever or night sweats
     

  • blood in sputum
     

Early action saves lives and prevents spread.

 

Long-Term Outlook After TB Treatment

Most individuals who complete treatment:

  • recover fully
     

  • regain normal lung function
     

  • return to daily activities
     

Long-term complications are rare with timely care.

 

Conclusion

Tuberculosis symptoms and treatment must be understood clearly to combat this preventable and curable disease. Persistent cough, fever, night sweats and weight loss should never be ignored. Early diagnosis, complete treatment adherence and regular follow-up are essential for curing TB and preventing transmission. With proper medical care and public awareness, tuberculosis can be effectively controlled and eliminated as a public health threat.


 

References

  • Indian Council of Medical Research (ICMR) – Tuberculosis Epidemiology and Treatment Guidelines
  • World Health Organization (WHO) – Global Tuberculosis Report
  • National Tuberculosis Elimination Programme (NTEP) – Government of India
  • Lancet Infectious Diseases – TB Diagnosis and Treatment Outcomes
  • National Family Health Survey (NFHS-5) – Infectious Disease Indicators
  • Statista – Global Tuberculosis Burden and Trends

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