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Published on: Jul 29, 2021
2 minute read
By: Raj Dwivedi

What Tests Are Used To Manage Anemia And What Do They Mean?

The doctors use a number of tests to diagnose anemia. Hb (hemoglobin) is one of the key indicators used in diagnosis. A hemoglobin test is a blood test that measures how much hemoglobin you have in your red blood cells. A hemoglobin test is generally used for detecting:

In addition, a hemoglobin test can also be carried out to assess bone marrow's response to treatment, evaluate possible blood donation and check the levels of red blood cells in the body. There are certain conditions that may interfere with the results of the hemoglobin test. In such cases, it is recommended to get the test done again.

For the hemoglobin test, a sample of your blood is taken and tested in a clinical laboratory [read more about the process here]. The results are expressed as grams of hemoglobin per deciliter (g/dL) or micrograms per liter (mcg/L). Normal range for this test is 12g/dL - 18g/dL (12.1-18.0 g/L) for adults and 9g/dL - 13g/dL (9.0-13.3 g/L) for children. If the test result comes out to be less than 7 gm, it can indicate a serious condition known as severe anemia. In some cases, the doctors may order follow-up tests to assess the current condition of the patient.

Apart from the hemoglobin test, certain other blood tests can be used for detecting low RBCs (RBC count) or abnormal types of RBC (red cell indices) or hemoglobin (Hb). These include complete blood count tests, reticulocyte tests, iron tests, and red blood cell indices.

In some cases, the doctor may opt to do a bone marrow aspiration and exam to check for any abnormalities in the bone marrow cells. In such cases, it of red blood cells is karyotype to rule out chromosomal disorders.

The most common reason for having an inadequate number of red blood cells in the body is an iron deficiency or anemia. Iron plays a significant role in the production of hemoglobin, which is responsible for carrying oxygen from the lungs to the tissues of other parts of the body. Hence, people suffering from iron are known as sickle cell trait. The tests include:

Complete blood count test - The complete blood cell count (CBC) is a routine test that checks the different components of your blood like number of red blood cells, white blood cells and platelets. It also has information about the size and hemoglobin content in each of these cells. A CBC includes tests for the following:

Reticulocyte test - This is a blood test that measures the reticulocytes (immature red blood cells) in the bloodstream. A high level of reticulocytes can indicate increased production of red blood cells by the bone marrow to compensate for anemia, or destruction of very early stage RBCs which are still unable to mature.

Iron tests - Iron is an essential component for RBC production. A test to assess the iron level in your blood is called a serum ferritin test, which measures the amount of iron stored in the body's cells and tissues. Another way to evaluate low iron levels is by carrying out a transferrin saturation test. In this case, the lab technician will extract serum from your blood sample and measure the amount of transferrin protein present in it. Transferrin is a protein that carries iron to the bone marrow where red blood cells are produced. Thus, if there is an insufficient amount of transferrin protein present in the serum, it shows that there is an inadequate level of stored iron.

Hemoglobin tests - A hemoglobin test is generally carried out to detect anemia, especially if the result of CBC tests are inconclusive. During this test, a small sample of blood is collected from your vein and sent to the laboratory for analysis. The test measures the amount of hemoglobin in your red blood cells.

Red cell indices - Red cell indices are tests that measure the size and hemoglobin content of the red blood cells. The values obtained from these tests can be used to detect anemia and other blood disorders.

Karyotype test - It is a lab test used to evaluate chromosomal abnormalities in red blood cells or bone marrow cells

Low blood cell counts also have other causes, such as infections or tumors. In some cases, low blood cells may indicate a more serious condition like bone marrow failure which requires immediate medical intervention to save the patient from death.

Thus, if you are suffering from any of these conditions and symptoms and suspect that you may be anemic, check with your doctor for the necessary tests to confirm or rule out your suspicions. Early detection and treatment of anemia can save you from serious complications like heart attacks, strokes, blood clots, etc.

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Genetic Predisposition Testing India: Understanding Your DNA to Prevent Future Disease

Genetics plays a significant role in determining an individual’s risk for various diseases. In India, where chronic illnesses like diabetes, heart disease, cancer, and neurological disorders are increasing rapidly, genetic predisposition testing has emerged as a powerful preventive tool. It helps individuals understand inherited risk factors long before symptoms appear, allowing timely intervention.

SecondMedic offers guided genetic screening to help patients uncover DNA-based risks and take proactive control of their long-term health.

What Is Genetic Predisposition Testing?

Genetic predisposition testing analyzes a person’s DNA to identify mutations, variations, or inherited markers associated with increased disease risk. It does not diagnose a disease but reveals how likely an individual is to develop certain conditions.

What the test identifies:

Gene mutations
Family-linked disease patterns
Hereditary cancer markers
Metabolic and cardiovascular risks
Neurological conditions
Autoimmune predispositions

These insights help individuals and doctors make informed preventive health decisions.

Why Genetic Testing Is Growing in India

1. High prevalence of lifestyle and hereditary diseases

India is the diabetes capital of the world, and many metabolic disorders have genetic roots.

2. Increasing cancer burden

BRCA and other hereditary cancer syndromes are being detected more often.

3. Awareness about preventive healthcare

People want to act early rather than wait for disease onset.

4. Growth of digital healthcare

Easy access through telemedicine platforms like SecondMedic.

5. Rising chronic cases at younger ages

Genetic predispositions often accelerate early onset of disease.

What Diseases Can Genetic Testing Predict?

1. Cancer Risk

Includes hereditary cancers such as:

Breast
Ovarian
Colorectal
Prostate
Pancreatic

BRCA1, BRCA2, and Lynch syndrome genes are key markers.

2. Heart Disease & Hypertension

Genes that influence:

Cholesterol levels
Plaque formation
Blood pressure regulation

3. Diabetes

Genes that affect insulin sensitivity and metabolic function.

4. Obesity

Markers linked to appetite regulation and fat storage.

5. Neurological Disorders

Including Alzheimer’s, Parkinson’s, and epilepsy predispositions.

6. Autoimmune Diseases

Genes related to lupus, rheumatoid arthritis, and thyroid disorders.

7. Drug Response (Pharmacogenomics)

DNA determines how the body reacts to certain medications.

How Genetic Predisposition Testing Works

Step 1: Sample Collection

Usually saliva, blood, or buccal swab.

Step 2: DNA Sequencing

Advanced technology identifies variations in your genome.

Step 3: Risk Analysis

Gene mutations are mapped to known disease risks.

Step 4: Expert Interpretation

SecondMedic’s genetic counsellors and doctors review results.

Step 5: Preventive Plan

Includes recommended lifestyle changes, screenings, and monitoring.

Benefits of Genetic Predisposition Testing

1. Detect Risk Before Symptoms

Allows decades of preventive action.

2. Personalized Health Planning

Diet, exercise, and medical screening tailored to DNA.

3. Early Cancer Detection

Essential for women with hereditary breast/ovarian cancer risk.

4. Family Health Insights

Identifies conditions that may affect children and siblings.

5. Improved Treatment Outcomes

Knowing your risk helps doctors monitor you more closely.

6. Better Drug Selection

Pharmacogenomics ensures medications match your genetic profile.

Who Should Consider Genetic Testing?

People with family history of cancer
Individuals whose relatives had early heart attacks
Families with diabetes across generations
Women with breast or ovarian cancer history
Couples planning pregnancy
People with unexplained chronic conditions
Individuals wanting personalized preventive healthcare

Limitations of Genetic Testing

1. Not a diagnosis

It shows probability, not certainty.

2. Environmental and lifestyle factors still matter

Genes interact with habits and environment.

3. Requires professional interpretation

Raw results without counselling can be confusing.

SecondMedic ensures accurate guidance through experienced specialists.

How SecondMedic Supports Genetic Testing

1. End-to-End Genetic Screening

From sample collection to detailed analysis.

2. Expert Review

Genetic counselors and doctors explain every risk factor.

3. Personalized Preventive Plan

Nutrition, exercise, and screening based on DNA.

4. Confidential Reporting

All data is securely stored.

5. Integrated Preventive Tracking

Follow-up tests and monitoring for high-risk individuals.

Future of Genetic Testing in India

AI-based genome interpretation
Affordable whole-genome sequencing
Predictive analytics for early cancer
Family-wide health risk mapping
Integration with digital health IDs under ABDM

SecondMedic aims to make genetic screening widely accessible and scientifically guided.

Conclusion

Genetic predisposition testing India empowers individuals by revealing inherited disease risks long before symptoms develop. It supports preventive healthcare, early cancer detection, and personalized wellness planning. With platforms like SecondMedic offering expert-guided genetic testing, Indians can now take proactive control of their long-term health.

To book your genetic test, visit www.secondmedic.com

References

ICMR – Genetic research insights
NIH – Genetic testing guidelines
WHO – Genomic medicine developments
Statista – DNA testing market India
SecondMedic genetic health studies

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