• Published on: Jul 29, 2021
  • 2 minute read
  • By: Raj Dwivedi

What Tests Are Used To Manage Anemia And What Do They Mean?

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The doctors use a number of tests to diagnose anemia. Hb (hemoglobin) is one of the key indicators used in diagnosis. A hemoglobin test is a blood test that measures how much hemoglobin you have in your red blood cells. A hemoglobin test is generally used for detecting:

In addition, a hemoglobin test can also be carried out to assess bone marrow's response to treatment, evaluate possible blood donation and check the levels of red blood cells in the body. There are certain conditions that may interfere with the results of the hemoglobin test. In such cases, it is recommended to get the test done again.

For the hemoglobin test, a sample of your blood is taken and tested in a clinical laboratory [read more about the process here]. The results are expressed as grams of hemoglobin per deciliter (g/dL) or micrograms per liter (mcg/L). Normal range for this test is 12g/dL - 18g/dL (12.1-18.0 g/L) for adults and 9g/dL - 13g/dL (9.0-13.3 g/L) for children. If the test result comes out to be less than 7 gm, it can indicate a serious condition known as severe anemia. In some cases, the doctors may order follow-up tests to assess the current condition of the patient.

Apart from the hemoglobin test, certain other blood tests can be used for detecting low RBCs (RBC count) or abnormal types of RBC (red cell indices) or hemoglobin (Hb). These include complete blood count tests, reticulocyte tests, iron tests, and red blood cell indices.

In some cases, the doctor may opt to do a bone marrow aspiration and exam to check for any abnormalities in the bone marrow cells. In such cases, it of red blood cells is karyotype to rule out chromosomal disorders.

The most common reason for having an inadequate number of red blood cells in the body is an iron deficiency or anemia. Iron plays a significant role in the production of hemoglobin, which is responsible for carrying oxygen from the lungs to the tissues of other parts of the body. Hence, people suffering from iron are known as sickle cell trait. The tests include:

Complete blood count test - The complete blood cell count (CBC) is a routine test that checks the different components of your blood like number of red blood cells, white blood cells and platelets. It also has information about the size and hemoglobin content in each of these cells. A CBC includes tests for the following:

Reticulocyte test - This is a blood test that measures the reticulocytes (immature red blood cells) in the bloodstream. A high level of reticulocytes can indicate increased production of red blood cells by the bone marrow to compensate for anemia, or destruction of very early stage RBCs which are still unable to mature.

Iron tests - Iron is an essential component for RBC production. A test to assess the iron level in your blood is called a serum ferritin test, which measures the amount of iron stored in the body's cells and tissues. Another way to evaluate low iron levels is by carrying out a transferrin saturation test. In this case, the lab technician will extract serum from your blood sample and measure the amount of transferrin protein present in it. Transferrin is a protein that carries iron to the bone marrow where red blood cells are produced. Thus, if there is an insufficient amount of transferrin protein present in the serum, it shows that there is an inadequate level of stored iron.

Hemoglobin tests - A hemoglobin test is generally carried out to detect anemia, especially if the result of CBC tests are inconclusive. During this test, a small sample of blood is collected from your vein and sent to the laboratory for analysis. The test measures the amount of hemoglobin in your red blood cells.

Red cell indices - Red cell indices are tests that measure the size and hemoglobin content of the red blood cells. The values obtained from these tests can be used to detect anemia and other blood disorders.

Karyotype test - It is a lab test used to evaluate chromosomal abnormalities in red blood cells or bone marrow cells

Low blood cell counts also have other causes, such as infections or tumors. In some cases, low blood cells may indicate a more serious condition like bone marrow failure which requires immediate medical intervention to save the patient from death.

Thus, if you are suffering from any of these conditions and symptoms and suspect that you may be anemic, check with your doctor for the necessary tests to confirm or rule out your suspicions. Early detection and treatment of anemia can save you from serious complications like heart attacks, strokes, blood clots, etc.

Read Blog
Inflammation

How Inflammation Affects Overall Health: Understanding the Hidden Risks

Inflammation is often misunderstood. While it is a vital protective response of the immune system, persistent or chronic inflammation can quietly damage tissues and increase the risk of serious diseases. Understanding how inflammation affects overall health is crucial in preventing long-term complications and maintaining optimal wellbeing.

According to the World Health Organization and global medical research published in Lancet, chronic inflammation is linked to a wide range of non-communicable diseases, including heart disease, diabetes and autoimmune disorders.

 

What Is Inflammation?

Inflammation is the body’s natural response to:

  • infection

  • injury

  • toxins

  • stress

It activates immune cells to eliminate harmful stimuli and promote healing.

There are two main types:

Acute Inflammation

Short-term and protective.
Examples include swelling after injury or fever during infection.

Chronic Inflammation

Long-term, low-grade inflammation that persists even without injury.

Chronic inflammation is harmful.

 

How Chronic Inflammation Develops

Persistent inflammation can result from:

  • unhealthy diet

  • sedentary lifestyle

  • obesity

  • chronic stress

  • environmental toxins

  • untreated infections

Modern lifestyle patterns contribute significantly to this condition.

 

Impact on Heart Health

Inflammation damages blood vessels and promotes plaque formation.

This increases risk of:

  • heart attack

  • stroke

  • hypertension

ICMR data highlights cardiovascular disease as a leading cause of death in India, with inflammation playing a contributing role.

 

Link Between Inflammation and Diabetes

Chronic inflammation interferes with insulin signalling.

This leads to:

  • insulin resistance

  • elevated blood sugar

  • metabolic syndrome

NFHS-5 data shows rising diabetes prevalence, partly linked to inflammatory lifestyle factors.

 

Effect on Joint and Muscle Health

Inflammatory processes contribute to:

  • arthritis

  • joint stiffness

  • muscle pain

Autoimmune diseases often involve chronic inflammation.

 

Gut Health and Inflammation

The gut plays a central role in immune regulation.

Poor diet and stress disrupt gut balance, triggering:

  • inflammatory bowel conditions

  • digestive discomfort

  • nutrient malabsorption

Gut inflammation impacts systemic health.

 

Brain Health and Inflammation

Emerging research suggests chronic inflammation affects:

  • memory

  • mood

  • cognitive performance

Inflammatory markers are associated with depression and neurodegenerative disorders.

 

Chronic Fatigue and Inflammatory Stress

Persistent inflammation causes:

  • ongoing fatigue

  • reduced stamina

  • sleep disturbances

The immune system remains in constant activation mode.

 

Role in Autoimmune Disorders

Autoimmune diseases occur when the immune system mistakenly attacks healthy tissues.

Chronic inflammation is central to conditions such as:

  • rheumatoid arthritis

  • lupus

  • inflammatory bowel disease

 

Signs of Chronic Inflammation

Symptoms may include:

  • unexplained fatigue

  • persistent joint pain

  • digestive issues

  • frequent infections

  • skin problems

Early detection is important.

 

Lifestyle Factors That Increase Inflammation

High Sugar Intake

Excess sugar promotes inflammatory pathways.

 

Processed Foods

Trans fats and additives trigger immune responses.

 

Sedentary Lifestyle

Lack of exercise reduces anti-inflammatory benefits.

 

Poor Sleep

Sleep deprivation increases inflammatory markers.

 

Chronic Stress

Elevated cortisol disrupts immune balance.

 

Natural Ways to Reduce Inflammation

Anti-Inflammatory Diet

Include:

  • leafy greens

  • fruits rich in antioxidants

  • nuts and seeds

  • whole grains

Avoid excessive processed foods.

 

Regular Physical Activity

Exercise lowers inflammatory markers and improves circulation.

 

Stress Management

Meditation and breathing exercises reduce stress hormones.

 

Adequate Sleep

7–8 hours of quality sleep supports immune regulation.

 

Maintain Healthy Weight

Excess abdominal fat produces inflammatory chemicals.

 

Role of Preventive Health Screening

Regular tests such as:

  • blood sugar

  • lipid profile

  • inflammatory markers

help monitor risk factors early.

 

Importance of Early Intervention

Unchecked inflammation increases risk of:

  • cardiovascular disease

  • metabolic disorders

  • organ damage

Timely lifestyle changes reverse early inflammatory effects.

 

Long-Term Health Benefits of Inflammation Control

Reducing inflammation supports:

  • heart health

  • stable blood sugar

  • improved immunity

  • enhanced cognitive function

  • reduced pain

Preventive strategies protect long-term wellbeing.

 

Conclusion

Understanding how inflammation affects overall health reveals its profound impact on the heart, brain, gut and metabolic systems. While acute inflammation protects the body, chronic inflammation silently contributes to major diseases. Fortunately, lifestyle changes such as balanced nutrition, regular exercise, quality sleep and stress management significantly reduce inflammatory burden. Prevention and early monitoring remain the most effective tools for protecting overall health and ensuring long-term vitality.

 

References

  • World Health Organization (WHO) – Chronic Disease and Inflammation Reports

  • Indian Council of Medical Research (ICMR) – Cardiovascular and Metabolic Health Studies

  • National Family Health Survey (NFHS-5) – Diabetes and Hypertension Data

  • NITI Aayog – Preventive Healthcare Strategy Reports

  • Lancet – Inflammation and Chronic Disease Research

See all

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