PREGNANCY PROFILE - C (FIRST TRIMESTER)11

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First Trimester Screening: A Doctor's Take on Early Pregnancy Evaluation

Hi there! I'm Dr. Kovid Pandey, and I'm here to explain the Pregnancy Profile C (First Trimester), a prenatal screening test offered during the early stages of your pregnancy. This test helps identify potential fetal abnormalities and provides valuable information for a healthy pregnancy journey.

What is First Trimester Screening?

First trimester screening is a combination of two tests performed in the first trimester (usually between 11 and 13 weeks) to assess your baby's risk of certain chromosomal abnormalities, such as:

• Down syndrome (Trisomy 21): This genetic condition results from having an extra copy of chromosome 21.
• Edwards syndrome (Trisomy 18): This serious condition occurs when a baby has three copies of chromosome 18 instead of the usual two.

The screening typically involves:

• Blood Test: This test measures the levels of two pregnancy hormones:
  • Beta-human chorionic gonadotropin (beta-hCG): Produced by the placenta, abnormally high levels can be associated with an increased risk of Down syndrome or trisomy 18.
  • Pregnancy-associated plasma protein-A (PAPP-A): Produced by the developing fetus and placenta, low levels may be linked to an increased risk of Down syndrome.
• Nuchal Translucency (NT) Scan: This painless ultrasound scan measures the fluid collection at the back of your baby's neck. Increased fluid thickness can be an indicator of certain chromosomal abnormalities.

Benefits of First Trimester Screening

• Early Detection: Early identification of potential risks allows for further diagnostic testing (if desired) and informed decision-making regarding your pregnancy.
• Peace of Mind: A low-risk result can offer reassurance about your baby's health during this crucial developmental stage.
• Improved Management: Identifying potential concerns may lead to additional monitoring or interventions to optimize your pregnancy care.

Why Might You Consider This Test?

While first trimester screening is not mandatory, it's often recommended for women with certain risk factors, such as:

• Advanced maternal age (35 years or older): Age increases the chance of chromosomal abnormalities.
• Family history: Having a close relative with a chromosomal abnormality raises your risk.
• Previous pregnancy complications: A history of miscarriage or a baby with a chromosomal abnormality may warrant screening.

Safety and Considerations

First trimester screening is a safe procedure for both you and your baby. The blood test is a simple finger prick, and the ultrasound scan uses sound waves, not radiation.

It's important to remember:

• Screening, not definitive: This test estimates risk, not a diagnosis. A high-risk result doesn't necessarily mean your baby has a problem. Further testing (amniocentesis or chorionic villus sampling) can confirm or rule out chromosomal abnormalities, but these procedures carry a small risk of miscarriage.
• Shared decision-making: Discuss the benefits and limitations of first trimester screening with your doctor. They will help you understand the results and guide you through any further testing options.

Additional First-Trimester Tests

• Combined First-Trimester Screening: This combines the blood test with the nuchal translucency scan for a more accurate risk assessment.

Second-Trimester Tests

• Quad Screen (Quadruple Marker Test): This blood test measures four different markers to assess the risk of chromosomal abnormalities.
• Maternal Serum Alpha-Fetoprotein (AFP) Test: This test measures the level of AFP in your blood. An abnormal level may indicate a neural tube defect in the baby.

Remember:

First trimester screening is a valuable tool for early pregnancy assessment. It can provide valuable information and empower informed decision-making. If you have any questions or concerns about this test or your pregnancy, please don't hesitate to talk to your doctor. They are your best resource for personalized guidance throughout your pregnancy journey.

PREGNANCY PROFILE - C (FIRST TRIMESTER) FAQs:

Q1. What is normal range for first trimester screening?
Ans: When Should I Have a First Trimester Screening? The blood screening is usually done between 9 and 14 weeks. Women who also get an ultrasound have one between 11 and 14 weeks.

Q2. How do you read first trimester screening results?
Ans: Your doctor may tell you the result of your test as a set of numbers.
         1. If the test is positive, your baby is more likely than normal to have trisomy 18 or Down syndrome.
         2. A negative result means that your baby probably doesn't have those birth defects.

Q3. What are the tests done in first trimester of pregnancy?
Ans: First trimester screening is a combination of fetal ultrasound and maternal blood testing. This screening process can help determine the risk of the fetus having certain birth defects. 
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Q4. What blood tests are done at 12 weeks pregnant?
Ans: Maternal blood test for PAPP-A and free β-HCG, done at 8-12 weeks (early is best). Maternal blood test for AFP, HCG and estriol (Triple test), done at 15-20 weeks.

Booking Procedure:

• Fill the booking form on right side with Name, Address, Mobile no.
• Blood/Urine samples will be collected from your Home address. 10-12 hrs fasting is required.
• You need to make the payment by cash to Thyrocare when Technician comes to pick up the samples OR Pay online after confirmation of booking.
• Reports will be couriered at your residence in 3-4 working days if hardcopy is opted. We will email the reports within 48-72 hrs on your email address mentioned while booking.

• Sample pickup at home
• Online reports within 48 hours